Objective To compare the effect of sodium hualuronate(SH)and platelet rich plasma(PRP)injections in the treatment of glenohumeral joint osteoarthritis(GJO).Methods Sixty-three patients with GJO were randomly assigned to receive either PRP(PRP group,n=29)or SH(SH group,n=34)injec-tions.The injections were administered into the glenohumeral joint under ultrasound guidance.The patients were assessed by the Visual Analogue Scale(VAS),American Shoulder and Elbow Surgeons(ASES)score and modified University of California(UCLA)shoulder joint score before injection and at 1,6,12 months of injection.Results There were no statistically significant differences in the general data between the two groups(P>0.05).Compared with before injection,the VAS scores at 1,6,and 12 months after injection in the two groups were significantly decreased(P<0.05).The VAS score at 12 months after injection in the SH group was significantly increased(P<0.05).The VAS score at 12 months after injection in the PRP group was lower than that in the SH group(P<0.05).The ASES scores showed a significant increase at 1 month after injection compared to before treatment(P<0.05),moreover the ASES scores at 6 months after injection in the PRP group were higher than those in the SH group(P<0.05).Compared with before injection,the modified UCLA shoulder joint scores at 1,6 months after injection in the two groups were significantly in-creased(P<0.05),moreover the scores of the modified UCLA shouder joint scores at 6 months after injec-tion in the PRP group were higher than those in the SH group(P<0.05).Conclusion Pain relief in intraar-ticular injection of PRP in GJO patients is more significant than intraarticular injection of SH,moreover PRP is significantly superior to SH in improving the shoulder joint function of the patients.

OBJECTIVE:To systematically review the efficacy and safety of Kanglaite injection combined with radiothreapy in the treatment of the non-small cell lung cancer (NSCLC),and provide evidence-based reference for clinical treatment. METH-ODS:Retrieved from PubMed,Cochrane Library,EMBase,VIP,CJFD,Wanfang database and CBM,randomized controlled tri-als(RCT)about the efficacy and safety of Kanglaite injection combined with radiothreapy in the treatment of NSCLC were collect-ed. Meta-analysis was performed by using Rev Man 5.3 software after data extraction and quality evaluation with modified Jadad scale. RESULTS:Totally 9 RCTs were included,involving 561 patients. Results of Meta-analysis showed,Kanglaite injection com-bined with radiothreapy can significantly improve the effective rate [OR=2.99,95%CI(2.07,4.31),P<0.001] and improvement rate of life quality [OR=3.74,95%CI(2.36,5.92),P<0.001],and reduce the incidence of radiation pneumonitis [OR=0.23,95%CI (0.12,0.47),P<0.001] and radiation esophagitis [OR=0.10,95%CI(0.05,0.21),P<0.001] of NSCLC patients,the differences were statistically significant. CONCLUSIONS:Both the efficacy and safety of Kanglaite injection combined with radiothreapy in the treatment of NSCLC are superior to radiothreapy alone.