Objective: By observing the effects of electroacupuncture (EA) on the apoptosis of conjunctival cells of rabbits with dry eye syndrome (DES) and the expressions of apoptosis-related proteins Caspase-3, Fas and Bcl-2, to discuss the mechanism of EA in the treatment of DES from the perspective of cell apoptosis. Methods: Male New Zealand rabbits were randomly divided into a normal group (NG), a model group (MG), an EA group (EAG) and a sham EA group (SEAG). DES rabbit model was developed by eye drop of 0.1％ benzalkonium chloride. The rabbit tear secretion and tear film break-up time (BUT) were measured; terminal deoxynucleotidyl transferase- mediated dUTP nick end labeling (TUNEL) assay was used to detect the apoptosis of conjunctival cells; the expressions of Caspase-3, Fas and Bcl-2 proteins in conjunctival cells were detected by immunohistochemistry. Results: Compared with the NG, the rabbit tear secretion decreased and the BUT was shortened in the MG (both P<0.01); compared with the MG and the SEAG, the rabbit tear secretion increased and the BUT was prolonged in the EAG (all P<0.05). Compared with the NG, the apoptosis of rabbit conjunctival cells increased (P<0.01), the expressions of Caspase-3 and Fas proteins increased (both P<0.05), and the expression of Bcl-2 protein decreased (P<0.01) in the MG; compared with the MG and the SEAG, the apoptosis of rabbit conjunctival cells decreased (both P<0.01), the expressions of Caspase-3 and Fas proteins decreased (all P<0.05), and the expression of Bcl-2 protein increased (both P<0.01) in the EAG. Conclusion: EA can inhibit the apoptosis of rabbit conjunctival cells, down-regulate the expressions of apoptosis-related proteins Caspase-3 and Fas, and up-regulate the expression of Bcl-2 protein, which may be one of the mechanisms of EA in treatment of DES.

Objective To summarize the safety and experience of operative cooperation of the laparoscopic transhiatal proximal gastrectomy therapy for esophagogastric junction adenocarcinoma.Methods Totals of 98 cases with esophagogastric junction adenocarcinoma underwent the treatment of laparoscopic transhiatal proximal gastrectomy were analyzed and summarized.Results Totals of 96 patients underwent laparoscopic transhiatal proximal gastrectomy successfully and 2 converted to open operation (one patient combined splenectomy and the other combined splenectomy and resection of the tail of the pancreas).The mean operative time was (224.1 ± 33.7) main and the mean blood loss was (69.4 ±26.1) ml.The mean length of esophageal resection was (4.0 ± 0.6) cm and no cancer cells were found in the incision edge.The number of lymph nodes removed was (16.4 ± 5.7).Among 96 patients,pleural laceration occurred 14 cases and spleen injury occurred 3 cases,no postoperaive mortalities happened.After follow-up from 3 month to 30 month,5 patients died.Conclusions Fully preoperative assessment and closely cooperation of operation team are important for the laparoscopic transhiatal proximal gastrectomy therapy for esophagogastric junction adenocarcinoma,which have a good short-term clinical effects.

Growth hormone deficiency is the medical condition of inadequate production of growth hormone. Growth hormone deficiency in adults is not common, but it may feature a diminished, lean body mass, poor bone density and a number of physical and psychological symptoms, including poor memory, social withdrawal and even depression. Abnormally low growth hormone levels in adults typically result in a diminished quality of life and it can even be disabling. The physical symptoms include loss of strength, stamina, and musculature. Growth hormone deficiency can also impair the biological and physiological/functional substrate of penile erection, which can be, at least in part, restored by the normalization of the plasma levels of growth hormone. This is a report on a 63-year-old man who suffered with severe erectile dysfunction and loss of libido due to growth hormone deficiency. Upon growth hormone administration, his erectile function improved dramatically.
Adult ; Bone Density ; Depression ; Erectile Dysfunction ; Growth Hormone ; Humans ; Libido ; Male ; Memory ; Middle Aged ; Penile Erection ; Plasma ; Quality of Life