1.Short-term efficacy of endoscopic submucosal dissection for early carcinoma in the remnant stomach
Ying ZHOU ; Qi JIANG ; Baisheng CHEN ; Xia WU ; Qiuli JIANG ; Nashan LI ; Xingyu WU ; Pinghong ZHOU ; Weifeng CHEN ; Jianwei HU
Chinese Journal of Clinical Medicine 2025;32(4):620-626
Objective To explore the short-term efficacy of endoscopic submucosal dissection (ESD) in the treatment of early carcinoma in the remnant stomach. Methods A retrospective study was conducted on 45 patients with early residual gastric cancer underwent ESD at the Endoscopy Center of Zhongshan Hospital, Fudan University from December 2014 to April 2024, with a total of 45 lesions. The patients were divided into an anastomotic group (n=15) and a non-anastomotic group (n=30) based on the location of tumor occurrence, and their clinical data, endoscopic diagnosis and treatment, and histopathological conditions were compared between the two groups. Results All 45 patients had lesions with redness and erosion. There were 9 cases of poor lifting of submucosal injection in the anastomotic group and 2 cases in the non-anastomotic group, respectively, and the difference was statistically significant (P<0.05). ESD surgery was performed on 13 lesions in the anastomotic group and 28 lesions in the non-anastomotic group, with surgery times of 80.00 (50.00, 100.00) min and 55.00 (43.75, 80.00) min, respectively. The difference in surgery time between the two groups was statistically significant (P=0.03). Among the 45 patients, ESD surgery achieved curative resection in 35 cases, including 11 cases in the anastomotic group and 24 cases in the non-anastomotic group, with no statistically significant difference. Conclusions Careful preoperative evaluation of early carcinoma in the remnant stomach is essential to prevent oversight. Lesions at anastomotic sites and suture lines present higher technical challenges for complete resection. ESD is safe and effective, with auxiliary traction technique available when necessary.
2.Research on privacy concerns in medical data based on the protection motivation theory
Chinese Medical Ethics 2024;37(1):45-53
Medical data governance and patient privacy protection have become important contents and hot topics in the process of medical informatization,and privacy concerns have gradually become a research focus.By drawing on the Internet Users'Information Privacy Concerns Scale and Protection Motivation Theory,this paper constructed a general model of patient privacy concerns in medical data.Empirical data was collected in the form of a questionnaire survey,and the hypotheses were validated using factor analysis and structural equation models.The results showed that the severity and likelihood of threats had a significant positive impact on privacy concerns,self-efficacy negatively affected privacy concerns,and privacy concerns positively affected behavioral willingness to privacy protection.Based on these,relevant organizations should strengthen privacy data management,improve data transparency,promote the value of data utilization,and strive to achieve a balance between privacy protection and data use.
3.A third dose of inactivated vaccine augments the potency, breadth, and duration of anamnestic responses against SARS-CoV-2.
Zijing JIA ; Kang WANG ; Minxiang XIE ; Jiajing WU ; Yaling HU ; Yunjiao ZHOU ; Ayijiang YISIMAYI ; Wangjun FU ; Lei WANG ; Pan LIU ; Kaiyue FAN ; Ruihong CHEN ; Lin WANG ; Jing LI ; Yao WANG ; Xiaoqin GE ; Qianqian ZHANG ; Jianbo WU ; Nan WANG ; Wei WU ; Yidan GAO ; Jingyun MIAO ; Yinan JIANG ; Lili QIN ; Ling ZHU ; Weijin HUANG ; Yanjun ZHANG ; Huan ZHANG ; Baisheng LI ; Qiang GAO ; Xiaoliang Sunney XIE ; Youchun WANG ; Yunlong CAO ; Qiao WANG ; Xiangxi WANG
Protein & Cell 2024;15(12):930-937
4.Analysis of Interest Temptation in Medical Human Trials
Yuanpeng REN ; Xinrui JIN ; Baisheng JIANG
Chinese Medical Ethics 2017;30(2):241-244
Interest temptation is a relatively hidden improper activity in medical human trials.Improper influence brought by interest temptation mainly displays allure in mind on subjects,which may lead them to make unreal promise.To avoid interest temptation and the undue influence,it needs to essentially distinguish interest temptation and interest sharing,apply different rules to different types of the subjects and strengthen the supervision function of institutional ethics committee.
5.Comparative study of MRI patterns of medial patellofemoral ligament injury in adolescents and adults after acute lateral patellar dislocation
Lei ZHENG ; Guangying ZHANG ; Luming LIU ; Baisheng SUN ; Jiquan DU ; Hui JIANG ; Bin ZHAO
Chinese Journal of Radiology 2013;47(10):903-907
Objective To compare and analyze MRI characteristics of medical patellofemoral ligament(MPFL) injury patterns in adolescents and adults after acute lateral patellar dislocation.Methods MR images of 42 adolescents and 45 adults after acute lateral patellar dislocation were retrospectively reviewed.Routine MR scanning was performed in axial,sagittal and coronal planes,including T1 WI,T2 WI and fat saturation sequence.The x2-tests were performed to analyze the MPFL injury patterns between adolescent group and adult group.Results The prevalence rate of MPFL injury was 97.6% (41/42) in adolescent group after acute lateral patellar dislocation,including 57.1% (24/42) of complete tear and 40.5% (17/42) of partial tear.The prevalence rate of MPFL injury was 100.0% (45/45) in adult group,including 64.4% (29/45) of complete tear and 35.6% (16/45) of partial tear.There were no statistical difference between adolescents and adults in prevalence rate of MPFL injury,complete MPFL tear,partial MPFL tear (x2 =1.084,0.486,0.223 ; P > 0.05).The prevalence rate of MPFL injury at femoral attachment,patellar attachment and midsubstance were 31.0% (13/42),78.6% (33/42) and 26.2% (11/42) respectively in adolescent group,whereas they were 64.4% (29/45),40.0% (18/45) and 15.6% (7/45) respectively in adult group.It occurred at multiple sites in 33.3% (14/42) of adolescents,and in 15.6% (7/45) of adults.There were significant differences between adolescents and adults in the prevalence rate of MPFL tear at femoral attachments and patellar attachments (x2 =9.759,13.324 ; P < 0.05),but there was no statistical difference at its midsubstance (x2 =1.497,P > 0.05).Although not statistically significant (x2 =3.749,P > 0.05),MPFL tear at multiple locations were seen more in adolescents than in adults (33.3% vs.15.6%).Conclusion The injury degree and distribution of MPFL are similar in adolescents and adults after acute lateral patellar dislocation,but there is significant difference in the site of MPFL injury distribution between adolescents and adults.MPFL is most easily injured at femoral attachment,secondly at patellar attachment in adults,while MPFL is most easily injured at patellar attachment,secondly at femoral attachment in adolescents.Adolescents are more likely to have multiple-site MPFL injury than adults.

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