1.Low vital capacity:an independent risk factor for functional outcome in SCI patients
Baijie XUE ; Xia HE ; Xiangbo WU
Chinese Journal of Rehabilitation Medicine 2024;39(8):1149-1154,1161
Objective:To investigate the correlation between basic lung function indicators and functional prognosis of spi-nal cord injury (SCI),and provide a basis for accurately judging the prognosis and improving the recovery ef-fect in the early clinical stage.Method:A retrospective analysis was made of 398 patients who met the inclusion and exclusion criteria in thedepartment of rehabilitation medicine of the first affiliated hospital of the air force military medical universityfrom June 2018 to May 2022. The data of patients' age,sex,body mass index (BMI),time from admission to injury,length of stay,ASIA classification and injury level,hematological indicators (white blood cell count,red blood cell count,hemoglobin concentration),and basic lung function test indicators at admission in-cluding tidal volume (VT),vital capacity (VC),forced vital capacity (FVC),forced expiratory volume in one second (FEV1),forced expiratory volume in one second/forced vital capacity (FEV1/FVC),peak expirato-ry flow (PEF),25% forceful exhalation forced expiratory flow at 25% of FVC exhaled(FEF25),forced expira-tory flow at 50% of FVC exhaled(FEF50),forced expiratory flow at 75% of FVC exhaled(FEF75),maximal voluntary ventilation (MVV),maximal voluntary ventilation/maximal predicted voluntary ventilation (MVV/MVVpre) were collected. The mean relative function gain (mRFG) of the modified Barthel index was used as the dependent variable,and the unit and multiple linear regression methods were used to identify the relevant factors affecting the prognosis of SCI patients,especially the underlying lung function indicators.Result:The single and multiple linear regression analysis showed that the prognosis of SCI patients was signifi-cantly related to the ASIA classification (B=11.064,P=0.019),length of stay (B=0.125,P=0.005) and VC (B=5.177,P=0.014). The cut-off value for VC judging the prognosis of SCI patients was 2.39L.Conclusion:Low VC is an independent risk factor for functional outcome in patients with SCI.The detection of basic lung function at the time of admission can help to judge the functional prognosis of patients with SCI. For the patients with VC below 2.39L,the prognosis is worse. Close attention should be paid to these patients,and more adequate rehabilitation treatments should be involved to maximize the improvement of pa-tients' daily living ability.
2.Low vital capacity:an independent risk factor for functional outcome in SCI patients
Baijie XUE ; Xia HE ; Xiangbo WU
Chinese Journal of Rehabilitation Medicine 2024;39(8):1149-1154,1161
Objective:To investigate the correlation between basic lung function indicators and functional prognosis of spi-nal cord injury (SCI),and provide a basis for accurately judging the prognosis and improving the recovery ef-fect in the early clinical stage.Method:A retrospective analysis was made of 398 patients who met the inclusion and exclusion criteria in thedepartment of rehabilitation medicine of the first affiliated hospital of the air force military medical universityfrom June 2018 to May 2022. The data of patients' age,sex,body mass index (BMI),time from admission to injury,length of stay,ASIA classification and injury level,hematological indicators (white blood cell count,red blood cell count,hemoglobin concentration),and basic lung function test indicators at admission in-cluding tidal volume (VT),vital capacity (VC),forced vital capacity (FVC),forced expiratory volume in one second (FEV1),forced expiratory volume in one second/forced vital capacity (FEV1/FVC),peak expirato-ry flow (PEF),25% forceful exhalation forced expiratory flow at 25% of FVC exhaled(FEF25),forced expira-tory flow at 50% of FVC exhaled(FEF50),forced expiratory flow at 75% of FVC exhaled(FEF75),maximal voluntary ventilation (MVV),maximal voluntary ventilation/maximal predicted voluntary ventilation (MVV/MVVpre) were collected. The mean relative function gain (mRFG) of the modified Barthel index was used as the dependent variable,and the unit and multiple linear regression methods were used to identify the relevant factors affecting the prognosis of SCI patients,especially the underlying lung function indicators.Result:The single and multiple linear regression analysis showed that the prognosis of SCI patients was signifi-cantly related to the ASIA classification (B=11.064,P=0.019),length of stay (B=0.125,P=0.005) and VC (B=5.177,P=0.014). The cut-off value for VC judging the prognosis of SCI patients was 2.39L.Conclusion:Low VC is an independent risk factor for functional outcome in patients with SCI.The detection of basic lung function at the time of admission can help to judge the functional prognosis of patients with SCI. For the patients with VC below 2.39L,the prognosis is worse. Close attention should be paid to these patients,and more adequate rehabilitation treatments should be involved to maximize the improvement of pa-tients' daily living ability.
3.The application of an end-effector-based lower limb robot to the gait training of stroke survivors
Jianzhou ZHU ; Hua YUAN ; Li MAO ; Shuya WANG ; Baijie XUE ; Fei TIAN ; Xiang MOU ; Huilin LIU ; Xu HU
Chinese Journal of Physical Medicine and Rehabilitation 2021;43(7):631-634
Objective:To observe the effect of gait training assisted by an end-effector-based robot on the gait, balance, walking and general lower limb motor functioning of stroke survivors.Methods:Thirty-nine stroke survivors were randomized into a training group ( n=21) and a control group ( n=18). In addition to routine hemiplegia rehabilitation, the control group was given medium frequency electrical stimulation while the training group underwent 20 minutes of gait training assisted by an end-effector-based robot six days a week for 4 weeks. Before and after the intervention, both groups were evaluated using the functional ambulatory categories (FAC), the Fugl-Meyer lower extremity assessment, the Wisconsin Gait Scale and the Berg balance scale (BBS). Results:There were no significant differences between the groups before the intervention. Afterward significant improvement was observed in both groups in all measurements, with the training group scored better in terms of FAC and BBS.Conclusion:Using an end-effector-based robot in gait training might be more advantageous for improving the gait, balance, walking and general lower limb functioning of stroke survivors.
4.Application value of dual-source CT urography with stellar photon detectors in the diagnosis of gout
Shouqi MO ; Yilan LI ; Baijie XU ; Xiaoqian XUE ; Weipeng HUANG ; Qiongyu YUAN ; Chaopeng WAN ; Zhenshan WANG
Chinese Journal of Primary Medicine and Pharmacy 2021;28(6):855-859
Objective:To investigate the application value of dual-source CT urography with stellar photon detectors in the diagnosis of gout.Methods:Forty patients who were diagnosed with gout according to American College of Rheumatology Guideline for the Diagnosis of Gout and received treatment between April 2018 and May 2020 were included in the observation group. Forty patients who were concurrently diagnosed with osteoarthritis and received treatment in the same hospital were included in the control group. All patients underwent dual-source CT urography with stellar photon detectors and corresponding biochemical index detection. Blood levels of uric acid, urea nitrogen, creatinine, total cholesterol, and triglyceride were compared between the observation and control groups.Results:Blood levels of uric acid, creatinine, urea nitrogen, total cholesterol, and triglyceride in the observation group were (519.38 ± 97.91) μmol/L, (110.21 ± 18.29) μmol/L, (12.21 ± 3.29) mmol/L, (6.49 ± 1.22) mmol/L, (3.45 ± 1.89) mmol/L, respectively, which were significantly higher than those in the control group (310.45 ± 61.40) μmol/L, (86.22 ± 13.12) μmol/L, (6.82 ± 1.75) mmol/L, (4.75 ± 0.56) mmol/L, (1.98 ± 0.85) mmol/L, respectively ( t = 11.43, 6.741, 9.148, 8.198, 4.486, all P < 0.05). Dual-source CT urography with stellar photon detectors revealed that urate crystals (color coded as green) were detected in 3 and 36 patients from the control and observation groups, respectively, with the detection rate of 7.5% (3/40) and 90% (36/40), respectively. There was significant difference in urate crystal detection rate between the observation and control groups ( χ2 = 24.993, P < 0.05). In the control group, no obvious destruction of bone, tendon and ligament were observed, urate deposition, total volume of (1.023 ± 0.83) cm 3, was found in feet and knee joint of a small number of patients. In the observation group, there were 30 patients with uric acid crystals and bone destruction in the metatarsophalangeal joint ( n = 6), distal tibia ( n = 7), distal fibula ( n = 3), proximal talus ( n = 4), proximal calcaneus ( n = 6), and wrist joint ( n = 4). There were 20 patients with ligament or tendon damage, involving deltoid ligament ( n = 2), Achilles tendon ( n = 10), and extensor and flexor tendon ( n = 53). Total volume of uric acid crystals was (32.22 ± 5.83) cm 3. The volume of uric acid crystals deposited in the hand, elbow, feet and knee was (8.00 ± 4.92) cm 3, (5.32 ± 2.75) cm 3, (36.00 ± 15.54) cm 3, and (13.31 ± 9.14) cm 3, respectively. Conclusion:Dual-source CT urography with stellar photon detectors has a high sensitivity in the diagnosis of gout, can accurately locate and quantify uric acid crystals and is of high application value in the diagnosis of gout.

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