Fibrous dysplasia is a benign disease of bone that may affect single or multiple bones. Craniofacial fibrous dysplasia may occur in a familial manner. This report deals with a patient who presented with multiple bony craniofacial prominences; with a positive family history of similar lesions. The lesions started to appear at his early teenage years and new lesions continued to arise and grow till 18 years of age. The lesions were expansile causing esthetic impairment. The case was diagnosed as a familial form of craniofacial fibrous dysplasia. Surgical recontouring was performed to the lesion that formed the patient's chief complaint. Later on the fibro-osseous lesion crept into the pulp canals of the related teeth causing pulpitis. Craniofacial fibrous dysplasia presentation varies according to the area affected, but it generally has a favorable diagnosis. However, we do recommend that periodic vitality testing be performed for teeth in proximity of the lesion.

ABSTRACT Acromegaly is a devastating chronic slowly progressive disease. Its early diagnosis is a challenging issue that necessitates clinical suspicion of signs and symptoms as a first step. This report introduces an unusual early sign in the oral cavity that lead to the early diagnosis of an acromegaly case. A case of a healthy 40-year-old male patient presented with progressively growing multiple hard swellings in the upper and lower jaws. Clinical examination revealed bony hard multiple small spiky exostosis-like swellings, located at the maxillary and mandibular alveolar bones. An array of investigations revealed a 2-mm diameter pituitary tumour in MRI of sella. To the best of the author’s knowledge, this is the first report of spiky exostosis-like growths in the alveolar bone as an early sign of acromegaly. In this case, thorough examination of oral signs and symptoms was the first step for early diagnosis and hence, better prognosis for acromegaly.
Acromegaly--diagnosis