We report four cases of post coronavirus disease 2019 (COVID-19) condition in which the patients suffered from a severe sense of fatigue that was successfully treated with warming-tonifying therapy using bukuryoshigyakuto, allowing them to return to normal social life. All four patients were unable to engage in social or school activities and had difficulty performing daily living tasks. Initially, they were treated with Kampo formulas corresponding to the yang pattern, which proved ineffective. However, their sense of fatigue was relieved after starting bukuryosigyakuto. Case 1 (36-year-old man) was a latent yin-deficiency pattern, in which an electro-acupuncture test revealed his interior cold. In Case 2 (53-year-old man), Case 3 (17-year-old woman) and Case 4 (11-year-old boy), the administration of bukuryoshigyakuto was based on the presence of severe sense of fatigue, characterized by the need to lie down almost all day and worsening symptoms after walking several dozen meters or taking a bath. There have been some case reports of tonifying therapies being effective in treating post COVID-19 conditions which are considered examples of qi deficiency or qi and blood deficiency following acute infectious disease. Kampo therapy with warming-tonifying formulas may be useful for post COVID-19 conditions that correspond to a late yin stage pattern in the six stage classification, particularly those presenting with severe sense of fatigue.

Purpose: We examined the safety and efficacy of cataract surgery and postoperative management in our hospital and at the homes of the patients who live on medically underserved remote.
Patients and methods: A total of 27 patients (54 eyes), who were followed in our hospital or at their homes were enrolled in this study. Cataract surgery was performed on them between January 2009 and January 2010 and we could follow up six months postoperatively. We divided these patients into two groups:group I (GI) consisted of 13 patients who could come to our hospital regularly during both preoperative and postoperative periods, and group II (GII) consisted of 14 patients who could not come to our hospital regularly during either preoperative or postoperative periods. Cataract surgeries were performed on all the patients in GI and GII in our hospital. The patients in GI were hospitalized for three days and those in GII were for seven days. After cataract surgery, the patients in GI had their eyes checked regularly in our hospital and those in GII were in their homes where the doctor visited. Postoperative ophthalmic clinical tests were conducted to examine visual acuity, intraocular pressure and fundus.
Results: GI comprised three males and 10 females. Their age averaged 79.3. GII comprised four males and 10 females. Their age averaged 82.6. Preoperative ophthalmic examinations found that preoperative average visual acuity (LogMAR and decimal visual acuity in parentheses) and spherical equivalent in GI and GII were 0.69 (0.41), 0.80 (0.33) and -0.43 dioptors, -0.42 dioptors respectively, showing no significant differences between the two groups. Postoperative ophthalmic examinations found that, best corrected visual acuity (LogMAR) was significantly increased to 0.36 (0.66) and 0.44 (0.53) in GI and GII respectively, showing no significant differences either.
Conclusions: We concluded that we could get safe and efficient cataract surgery and postoperative management combined with prolonged hospitalization and house calls on the patients who live in the isolated islands.