1.Expert consensus on the medication catalog for drug-induced liver injury and rational drug use
Jianchun LI ; Di CHEN ; Pengfei JIN ; Gerontology NATIONAL ; Association GERIATRIC ; Research PHARMACY ; Society PHARMACY ; Association GERIATRIC
China Pharmacy 2026;37(3):273-280
OBJECTIVE To systematically sort out the drugs causing drug-induced liver injury (DILI) and their relevant information, and to develop the Expert consensus on the medication catalog for drug-induced liver injury and rational drug use (hereinafter referred to as the Consensus), so as to provide a reference for rational clinical use. METHODS Systematic searches were conducted across various literature databases, guideline retrieval websites and professional liver injury websites. Drugs identified as causing DILI from the included literature and online resources were extracted and assigned scores based on source credibility: three points for LiverTox A-class drugs and two points for B-class drugs; two points for drugs from Hepatox and guidelines; and one point for drugs from consensus and related literature sources. Drugs classified as LiverTox category A/B or with total scores ≥4 were included in the preliminary list of DILI-causing drugs. Opinions were collected and integrated from a multidisciplinary expert panel comprising 45 medical and pharmaceutical experts from 27 provinces across China through three rounds of the Delphi method (including questionnaires and discussion sessions), and after revision, the final version of Consensus was formed. RESULTS & CONCLUSIONS This Consensus included 12 traditional Chinese medicines (TCMs) such as Polygoni Multiflori Radix and Ephedrae Herba, 151 Western medicines including amiodarone and atorvastatin, along with rational use information. For TCM, eight rational use information were included: evidence-based score, liver injury classification based on pathogenesis, liver injury classification based on biochemical abnormality pattern, clinical phenotype, laboratory examination manifestations, latency period, recovery time, and management strategies. For Western medicines, six additional items were included based on the TCM, namely liver function monitoring, discontinuation, contraindications, cautions, dose adjustments, and risk factors, totaling 14 items. This Consensus systematically compiles DILI drugs and their rational use information, which will support clinicians in enhancing the prevention, identification, and management of DILI, reducing the incidence of liver injury, and ensuring patient medication safety and efficacy.
2.Expert Consensus on the Evaluation and Management of Obstructive Sleep Apnea in Patients With Cardiovascular Disease(2024 Edition)
National Expert Commission for Cardiovascular Diseases ; Cardiovascular Group,Chinese Academy Society of Sleep Medicine,Chinese Medical Doctor Association ; Geriatric Sleep Disorders and Cardiopulmonary Group,Division of Sleep Science and Technology,China Association of Gerontology and Geriatrics ; Qin LUO ; Zhihong LIU
Chinese Circulation Journal 2024;39(5):417-432
As cardiovascular disease(CVD)incidence and mortality rates continue to rise in China,the importance of identifying and managing CVD risk factors grows.Obstructive sleep apnea(OSA)is a prevalent sleep-related breathing disorder,affecting an estimated 936 million individuals aged 30-69 worldwide,with China leading globally with 176 million affected.Increasing research indicates a close association between OSA and the onset and progression of various CVD,significantly affecting outcomes.However,OSA has long been underrecognized and undertreated in CVD clinical practice.To address this,National Expert Commission for Cardiovascular Diseases,Cardiovascular Group,Chinese Academy Society of Sleep Medicine,Chinese Medical Doctor Association,and Geriatric Sleep Disorders and Cardiopulmonary Group,Division of Sleep Science and Technology,China Association of Gerontology and Geriatrics convened multidisplinary experts to formulate the"Expert Consensus on the Evaluation and Management of Obstructive Sleep Apnea in Patients With Cardiovascular Diseases(2024 Edition)".This consensus addresses core clinical issues such as screening,diagnosis,treatment,and follow-up of CVD patients with OSA.It offers 17 recommendations on common clinical questions,based on current evidence-based medicine,following extensive discussions and votes,aiming to standardize the assessment and management of OSA in Chinese CVD patients,support clinical decision-making,and improve clinical care and service quality.
3.Chinese Multidisciplinary Expert Consensus on Diagnosis and Management of Orthostatic Hypotension
Syncope Branch of Chinese Association of Geriatric Research ; Group of Parkinsons Disease and Movement Disorder,Chinese Society of Neurology,Chinese Medical Association ; Wenling LIU ; Haibo CHEN
Chinese Circulation Journal 2024;39(11):1058-1069
Orthostatic hypotension (OH) is a common cardiovascular symptom,divided into neurogenic and non-neurogenic categories according to pathophysiology,both of which are associated with impaired quality of life and potential adverse outcomes.Due to the complex influential factors,diagnosis and treatment often require multidisciplinary cooperation and individualization.But domestic doctors pay little attention to the diagnosis and treatment of OH.This consensus,co-authored by experts from relevant professional fields including cardiology,neurology and psychology,systematically describes the concept,pathophysiology,classification and clinical characteristics of OH.The recommendations on the diagnosis,evaluation and treatment of OH were put forward to improve the attention of clinicians to OH and their ability of diagnosis and treatment.
4.Service specification for senior care workers with traditional Chinese medicine specialty
Qi ZOU ; Qin TANG ; Lei WANG ; Jiawei GENG ; Baofeng DENG ; Zhen YU ; Ayue AN ; Lixin WEI ; Xiaoying TONG ; Peijing RONG
Science of Traditional Chinese Medicine 2024;2(4):327-331
Senior care workers specializing in traditional Chinese medicine (TCM) healthcare have become an indispensable force in institutional care, community care, and home care. The first Chinese nursing service team aimed to improve the health of the elderly by providing continuous services for physical and mental well-being, disease prevention, physical amelioration, and overall health enhancement using TCM concepts, methods, and technologies. The primary purpose of formulating this TCM health and elderly care worker service specification was to standardize services within the TCM elderly care industry, ensuring that the elderly receive better health and elderly care services supported by technical expertise. This specification outlined the basic requirements for TCM health and elderly care workers, including standards for service content, service quality control, service evaluation, and improvement. It primarily focused on the content and requirements of TCM health and elderly care services, such as constitution identification, life care, acupoint healthcare, and TCM auxiliary nursing for elderly individuals with chronic diseases. This specification is applicable to TCM health and elderly care personnel at various levels of hospitals and healthcare institutions and is noted for its strong applicability and effectiveness.
5.Expert consensus on the management strategy of patients with hereditary ataxia during prevention and control of novel coronavirus pneumonia epidemic.
SPECIALIZED COMMITTEE OF NEUROGENETICS NEUROPHYSICIAN BRANCH OF CHINESE MEDICAL DOCTOR ASSOCIATION ; Hong JIANG ; Beisha TANG
Chinese Journal of Medical Genetics 2020;37(4):359-366
Since December 2019, a series of highly infectious cases of unexplained pneumonia have been discovered in Wuhan, Hubei Province, which have been confirmed as '2019 corona virus disease' caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 virus can invade many human systems including the lungs. Patients with central nervous system involvement may show a series of neurological symptoms, which is easy to be misdiagnosed and neglected, thereby increasing the risk of SARS-CoV-2 transmission. Hereditary ataxia is a large group of neurodegenerative diseases with great clinical and genetic heterogeneity and high mortality and disability. In view of the seriousness of the COVID-19 epidemic, a series of prevention and control measures adopted by the government have restricted the follow-up, diagnosis and treatment of patients by the hospitals, which has a great impact on their mental and physical health. In order to standardize the management of patients during the prevention and control of COVID-19 epidemic, the Specialized Committee of Neurogenetics of the Neurophysician Branch of Chinese Medical Doctor Association has formulated this consensus, with an aim to help patients to overcome the difficulties and pass the epidemic prevention period safely.
Betacoronavirus
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China
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epidemiology
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Consensus
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Coronavirus Infections
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complications
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epidemiology
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Epidemics
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Health Status
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Humans
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Mental Health
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Nervous System Diseases
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virology
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Pandemics
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Pneumonia, Viral
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complications
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epidemiology
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Spinocerebellar Degenerations
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complications
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diagnosis
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prevention & control
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therapy

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