Asians ; China ; Chronic Disease ; Consensus ; Female ; Heart Failure/therapy* ; Humans

Lung cancer is the most common malignancy with the highest incidence and mortality in China, which poses a major public health problem. To further standardize the prevention and treatment of lung cancer, improve the prognosis of patients, and provide professional evidence-based medical recommendations to medical professionals across China, the Oncology Society of Chinese Medical Association organized experts from departments of pulmonary medicine, oncology, thoracic surgery, radiotherapy, imaging, and pathology, based on indications approved by China Food and Drug Administration, domestically available drugs, recommendations of international guidelines and current clinical practice in China, integrated the latest evidence-based medical evidence of pathology, genetic testing, immune molecular biomarker detection and treatment methods of lung cancer in recent years. After consensus meetings, the Chinese Medical Association guideline for clinical diagnosis and treatment of lung cancer in China was formulated, which provided recommendations to clinicians, and imaging, laboratory, and rehabilitation professionals.
Asians ; China/epidemiology* ; Humans ; Lung Neoplasms/therapy* ; Medical Oncology ; Prognosis

OBJECTIVES: To study the characteristics of UGT1A1 gene mutations in Dong neonates in Sanjiang County of Liuzhou and its association with the pathogenesis of hyperbilirubinemia in Dong neonates. METHODS: A prospective analysis was performed on 84 neonates who were diagnosed with unexplained hyperbilirubinemia in the Department of Neonatology, Sanjiang County People's Hospital, from January 2021 to January 2022. Sixty healthy neonates born during the same period were enrolled as the control group. Peripheral blood genomic DNA was extracted for both groups, and UGT1A1 exon 1 was amplified by PCR and sequenced. RESULTS: In the case group, 33 neonates were found to have G71R missense mutation, with a mutation rate of 39%. The case group had a significantly higher frequency of A allele than the healthy control group (21% vs 10%, P<0.05). The risk of hyperbilirubinemia in Dong neonates carrying G71R missense mutation was 2.588 times as high as that in healthy neonates carrying wild-type UGT1A1 gene (P<0.05). Hardy-Weinberg equilibrium testing showed that the UGT1A1 G71R locus was in genetic equilibrium in both groups (P>0.05). CONCLUSIONS UGT1A1 G71R mutation is a high-frequency gene mutation type in Dong neonates in Sanjiang County, and G71R missense mutation is associated with hyperbilirubinemia in Dong neonates.
Asians/genetics* ; China ; Exons ; Glucuronosyltransferase/genetics* ; Humans ; Hyperbilirubinemia, Neonatal/genetics* ; Infant, Newborn ; Mutation

Asians ; China ; Humans ; Hypertension/drug therapy* ; Practice Guidelines as Topic ; Writing

Asians ; China ; Humans ; von Willebrand Diseases/therapy* ; von Willebrand Factor

ADAMTS13 Protein ; Asians ; China ; Humans ; Plasma Exchange ; Purpura, Thrombotic Thrombocytopenic/therapy*

Asians ; China ; Consensus ; Hematopoietic Stem Cell Transplantation/adverse effects* ; Humans ; Venous Thromboembolism/therapy*

Asians ; China ; Consensus ; Exercise Test ; Humans ; Medicine, Chinese Traditional ; Walk Test ; Walking

The Physical Activity Guidelines for Chinese(2021) consists of seven parts, including general guidelines, children aged 2 years and below, children aged 3-5 years, children and adolescents aged 6-17 years, adults aged 18-64 years, the elderly aged 65 years and above, and patients with chronic diseases. The development of this guideline is initiated by the Bureau for Diseases Prevention and Control of the National Health Commission, led by the Chinese Center for Disease Control and Prevention as well as China Institute of Sport Science, and finalized by the Composing and Editorial Board of Physical Activity Guidelines for Chinese.
Adolescent ; Adult ; Aged ; Asians ; Child ; China ; Chronic Disease ; Exercise ; Humans

Physical Activity Guidelines for Chinese (2021) is composed of seven parts, including the general guidelines, children aged 2 years and below, children aged 3-5 years, children and adolescents aged 6-17 years, adults aged 18-64 years, the elderly aged 65 years and above, and patients with chronic diseases. The guidelines is instructed by the Bureau for Diseases Prevention and Control of the National Health Commission, led by the Chinese Center for Disease Control and Prevention and China Institute of Sport Science and completed by the Composing and Editorial Board of Physical Activity Guidelines for Chinese.
Adolescent ; Adult ; Aged ; Asians ; Child ; Child, Preschool ; China ; Chronic Disease ; Exercise ; Humans ; Middle Aged ; Young Adult