1.A Case of Malignant Pleural Effusion Due to Urothelial Carcinoma
Akina KOIDE ; Kazuyoshi YAMADA ; Miki FUKAI ; Akio DOI ; Mikiko MIZUTANI ; Mayumi ITOH ; Masateru KITAJIMA ; Katsura YAMAGUCHI ; Eizo MIYATA ; Arisa TSUCHIMORI ; Takuji TSUYUKI ; Hiroki KUBOTA
Journal of the Japanese Association of Rural Medicine 2025;74(1):40-44
Malignant pleural effusion is characterized by fluid buildup between the lung and the chest wall due to cancer cells in the pleura. Most cases are caused by lung cancer, breast cancer, ovarian cancer, or malignant lymphoma. Urothelial carcinoma is a rare cause of malignant pleural effusions and is difficult to diagnose by cytological examination. We report a case of malignant pleural effusion due to urothelial carcinoma. An 80-year-old man presented with right back pain. After close examination, he was diagnosed with ureteral cancer. During the course of treatment, a unilateral pleural effusion was found, and cytological and histological examinations were performed on suspicion of malignant pleural effusion. Cytological examination revealed numerous round-to-ovoid cells with irregularly enlarged nuclei. Immunohistological studies were performed on cell block specimens, and urothelial carcinoma was diagnosed. Cytological examination of malignant pleural effusions may require estimation of the primary site. It is important to take a multifaceted approach that considers not only the cytological findings but also the clinical findings and medical history.
2.Impact of COVID-19 spread on visit intervals and clinical parameters for patients with periodontitis in supportive periodontal therapy:a retrospective study
Mizuho YAMAZAKI-TAKAI ; Yumi SAITO ; Shoichi ITO ; Moe OGIHARA-TAKEDA ; Tsuyoshi KATSUMATA ; Ryo KOBAYASHI ; Shuta NAKAGAWA ; Tomoko NISHINO ; Namiko FUKUOKA ; Kota HOSONO ; Mai YAMASAKI ; Yosuke YAMAZAKI ; Yuto TSURUYA ; Arisa YAMAGUCHI ; Yorimasa OGATA
Journal of Periodontal & Implant Science 2024;54(2):75-84
Purpose:
This study investigated the relationship between the number of days that hospital visits were postponed and changes in clinical parameters due to the spread of coronavirus disease 2019 (COVID-19), after the Japanese government declared a state of emergency in April 2020.
Methods:
Regarding the status of postponement of appointments, we analyzed the patients who had visited the Nihon University Hospital at Matsudo for more than 1 year for supportive periodontal therapy (SPT) and classified them into low-, moderate- and high-risk subgroups according to the periodontal risk assessment (PRA). Clinical parameters for periodontal disease such as probing depth (PD), full-mouth bleeding score (FMBS), full-mouth plaque score, periodontal inflamed surface area (PISA), and periodontal epithelial surface area (PESA) were analyzed in 2 periods, from October 2019 to March 2020 and after April 2020.Correlation coefficients between days of deferral and the degree of changes in clinical parameters were calculated.
Results:
The mean age of the 749 patients was 67.56±10.85 years, and 63.82% were female.Out of 749 patients, 33.24% deferred their SPT appointments after April 2020. The average total of postponement days was 109.49±88.84. The number of postponement days was positively correlated with changes in average PD (rs=0.474) and PESA (rs=0.443) in the high-risk subgroup of FMBS, and average PD (rs=0.293) and PESA (rs=0.253) in the highrisk subgroup of tooth number (TN). Patients belonging to the high-risk subgroups for both FMBS and TN had a positive correlation between postponement days and PISA (rs=0.56).
Conclusions
The findings, the spread of COVID-19 appears to have extended the visit interval for some SPT patients. Moreover, longer visit intervals were correlated with the worsening of some clinical parameters for SPT patients with high PRA.


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