1.Peri-Operative outcomes of abdominotransanal Resection with total mesorectal excision and coloanal anastomosis for primary distal rectal adenocarcinoma.
Omar O OCAMPO ; Marc Paul J LOPEZ ; Marie Dione P SACDANAL ; Manuel Francisco T ROXAS ; Hermogenes J MONROY III ; Catherine S CO ; Aramando C CRISOSTOMO ; Alberto B ROXAS
Philippine Journal of Surgical Specialties 2012;67(1):18-28
Background: This study aimmed to provide a local report on the peri-operative outcomes as well as the factors that cotribute to the development of complications on patients with primary distal rectal cancer who underwent abdominotransanal resection (ATAR) with total mesorectal excision (TME) and transanal handsewn coloanal anastomosis (CAA).Methods: This retrospective study was conducted by the Division of Colorectal Surgery of the Philippine General Hospital which evaluated 79 adult patients who underwent ATAR with TME and CAA due to primary distal rectal adenocarcinoma from january 1, 2008 to December 31, 2010. The variables such as age, general, comorbidities, pre-operative serum albumin level, smoking history, utilization of neoadjuvant therapy, distance of tumor from anal verge, surgical approach, quality opf surgical specimen, circumferential resection margin, pathologic stage, length of postoperative hospital stay, type of anesthesia, morbidity and mortality were recorded and analyzed.Results: Of the 79 patients, 19 patients (24.05%) had reported CAA dehiscence, 3 patients (3.8%) nessitated a relaparatomy with drainage of generakized intra-abdominal abscess, 6(7.59%) patients underwent transanal drainage of pelvic abscess and 10 (12.66%) patients who presented with pelvic abscess on computed tomography scan (3), purulent discharge with minor coloanal anastomotic disruption (3) and fistula (4) were managed non-operative. Diabetes mellitus (P=0.043) and history o0f smoking (p=0.037%) were found to be statistically significant factors associated with increased of CAA dehiscence.Conclusion: Diabetes mellitus and history of smoking lead to statistically significant increase in the development of anastomic dehiscence following ATAR with TME snd CAA for primary distal rectal cancer.
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