1.Development of Prediction Model for 1-year Mortality after Hip Fracture Surgery
Konstantinos ALEXIOU ; Antonios A. KOUTALOS ; Sokratis VARITIMIDIS ; Theofilos KARACHALIOS ; Konstantinos N. MALIZOS
Hip & Pelvis 2024;36(2):135-143
Purpose:
Hip fractures are associated with increased mortality. The identification of risk factors of mortality could improve patient care. The aim of the study was to identify risk factors of mortality after surgery for a hip fracture and construct a mortality model.
Materials and Methods:
A cohort study was conducted on patients with hip fractures at two institutions. Five hundred and ninety-seven patients with hip fractures that were treated in the tertiary hospital, and another 147 patients that were treated in a secondary hospital. The perioperative data were collected from medical charts and interviews. Functional Assessment Measure score, Short Form-12 and mortality were recorded at 12 months. Patients and surgery variables that were associated with increased mortality were used to develop a mortality model.
Results:
Mortality for the whole cohort was 19.4% at one year. From the variables tested only age >80 years, American Society of Anesthesiologists category, time to surgery (>48 hours), Charlson comorbidity index, sex, use of anti-coagulants, and body mass index <25 kg/m2 were associated with increased mortality and used to construct the mortality model. The area under the curve for the prediction model was 0.814. Functional outcome at one year was similar to preoperative status, even though their level of physical function dropped after the hip surgery and slowly recovered.
Conclusion
The mortality prediction model that was developed in this study calculates the risk of death at one year for patients with hip fractures, is simple, and could detect high risk patients that need special management.
2.Diffuse pigmented villonodular synovitis of the knee joint: 3-year follow-up of a case report
Antonios A. KOUTALOS ; Dimitrios RAGIAS ; Emmanouel RIZNIOTOPOULOS ; Konstantinos TSANADIS ; Emmanouil XYDIAS ; Nikolaos TSOUKALAS ; Nikolaos CHARALAMPAKIS ; Nikolaos TROGKANIS ; Maria IOANNOU ; Konstantinos N. MALIZOS ; Maria TOLIA
Radiation Oncology Journal 2022;40(4):270-275
Pigmented villonodular synovitis (PVNS) is a proliferative, recurrent and locally invasive disease of the synovium. The symptoms of the disorder are not typical and thus it is very often misdiagnosed. Most of the times, magnetic resonance imaging presents the nodular model of development and sets the basis for the diagnosis. The final diagnosis will be set by the pathological evaluation of the lesion’s biopsy. PVNS may be localized (nodule with a clear boundary with/without presence of single pedicle) or diffuse (extensive involvement of the adjacent nerves and vessels). Depending on the extension of the PVNS, a different management approach is performed, lesion excision vs. resection, followed by radiotherapy respectively. We report a case of diffuse PVNS in the knee joint, treated with surgical excision and adjuvant radiotherapy as well as follow-up imaging after a time period of 3 years.

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