This is a case of a 37-year-old nulliparous woman, and her 53-year-old husband diagnosed with complete retrograde ejaculation and absolute azoospermia, who conceived after transfer of embryos fertilized using cryopreserved sperm retrieved from postejaculatory urine. Four embryos were thawed, then transferred in the blastocyst stage, resulting in a singleton pregnancy and delivery by cesarean section at term to a healthy baby boy weighing 3100 g. This case study shows that cryopreservation of sperm retrieved from postejaculatory urine is feasible for IVF, despite demonstration of low motility. This is more cost-effective and least invasive as the husband may avoid surgical aspiration or extraction of sperm.
Cryopreservation ; Infertility ; Fertilization in Vitro

Mullerian duct anomalies (MDAs) are congenital defects of the female genital system that arise from abnormal embryological development of the Mullerian ducts. A didelphys uterus, also known as a "double uterus," is one of the least common amongst the MDAs. Reported here is a case of a 16 year old female with a uterus didelphys with the obstructed left hemiuteri adherent in the anterior abdominal wall, and an endometriotic cyst on the same side. She underwent hysteroscopy-guided vaginoscopy, laparoscopic left hemihysterectomy, left oophorocystectomy. Cases such as these require careful preoperative planning and diagnostic imaging for more accurate diagnosis and, hence, for the most appropriate surgical procedure to be carried out. 3D ultrasonography and Magnetic Resonance Imaging have been the most widely used imaging techniques. The goals of management are to relieve the symptoms of obstruction and to restore the normal anatomy as much as possible in order to provide the best chance for future fertility.
Uterine Didelphys

Presented are the first two reported cases of patients who underwent ovarian tissue vitrification in the Philippines. One case is a 22 year old nulligravid diagnosed with invasive Ductal Carcinoma Stage IIIA of the right breast (status post Modified Radical Mastectomy), and advised to undergo systemic chemotherapy with Doxorubicin and Cyclophosphamide. The other case is a 34 year old primary infertility patient, diagnosed with Non-keratinizing Squamous Cell Carcinoma of the Cervix. Stage 1B2, and was advised neoadjuvant platinum-based chemotherapy with concurrent radiotherapy and brachytherapy. Both women are desirous of pregnancy and so underwent ovarian tissue cryopreservation prior to medical management of their condition, to preserve future reproduction. 

Human ; Adult ; Cryopreservation ; Fertility