Objective To explore the outcome of vacuum sealing drainage in treating limb burns combined with seawater immersion.Methods Sixteen healthy male New Zealand white rabbits were randomly divided into conventional debridement group(8 rabbits)and vacuum sealing drainage group(8 rabbits)after limb burns and seawater immersion.The wound healing was observed in the 2 groups,and the wound tissue was collected immediately,7 days,and 14 days after modeling for HE staining to observe the histopathological changs and for immunohistochemistry to detect the expression of Ki67 and CD31.Results The healing time was significantly shorter in the vacuum sealing drainage group than that in the conventional debridement group after limb burns and seawater immersion.The expression of Ki67 and CD31 in the vacuum sealing drainage group were significantly higher than that in the conventional debridement group.Conclusion Vacuum sealing drainage is more beneficial to wound healing than conventional debridement.

The second class is not only a useful supplement to the first class but also an effective way to improve the comprehensive quality and ability of students.Through the deliberate research training and laboratory work,the second class of scientific research facilitates the medical students' developing scientific thinking,expanding professional knowledge,enhancing the ability to do scientific research and cultivating the spirit of teamwork.