Background: The COVID-19 pandemic has profoundly impacted mental health, particularly exacerbating conditions such as depression, anxiety, insomnia, post-traumatic stress disorder (PTSD), and emotional disorders among hospitalized patients. This study examined the prevalence of COVID-19-related mental health issues and risk factors in hospitalized patients affiliated with MNUMS, compared to a control group. Aim: To assess the prevalence of mental health disorders such as depression, anxiety, insomnia, and post-traumatic stress disorder (PTSD), and to identify their associated risk factors. Materials and Methods: The study was conducted at hospitals under MNUMS, including the Mongolian-Japanese Hospital, Central Hospital, and the National Center for Maternal and Child Health. A total of 552 participants (399 case group, 153 control group) who were hospitalized were included. Depression (PHQ-9≥10), anxiety (GAD-7≥10), insomnia (ISI≥15), and PTSD (PCL-5≥33) were assessed using standardized scales. Analysis was performed using chi-square tests and binary logistic regression (crude odds ratio [cOR]/adjusted odds ratio [aOR], 95% confidence interval [CI]), adjusted for group, age, and sex. Results: In the case group, depression (23.1% vs. 13.7%, p=0.015, cOR=1.884 [1.124-3.156]), anxiety (16.8% vs. 11.1%, p=0.096), and any mental disorder (18.0% vs. 13.7%, p=0.225) were higher, while insomnia was lower (19.5% vs. 30.1%, p=0.008). PTSD was low overall (1.8% vs. 0.7%, p=0.333). Risk factors included female sex (p<0.001, cOR=0.362 for depression in males), younger age (p=0.004), unemployment (p=0.017), and prior trauma (p<0.001). COVID-19 symptoms (difficulty breathing) increased the risk of depression (p<0.001, cOR=2.828 [1.708-4.682]). Conclusion Hospitalization for COVID-19 increases the risk of depression and anxiety, modulated by demographic, clinical, and socioeconomic factors. Targeted interventions for vulnerable groups are essential.

BACKGROUND. Chronic rhino-sinusitis (CRS) is a common inflammatory disease of the nose and paranasal sinuses, especially after virus infections. It has a significant impact on patients’ quality of life. We aimed to evaluate the clinical value of low-level laser therapy (LLLT) forpediatric chronic rhino-sinusitis. METHODS. 30 patients 6-15 years old with CRS were divided into two groups: T1 were treated twice a week and T2 were treated five times a week for 2 treatment sessions within 2 weeks. Laser irradiation was delivered on 12 points over each maxillary and frontal sinuses with 30 seconds and the total treatment duration was 180 seconds. The evaluation was performed by a total symptom score based on SNOT-22 questionnaires of pre and after treatments. RESULTS. The total symptom scoreimproved significantly (p<0.15) in 27 cases. CONCLUSION. This study indicates that LLLT applied for 4 weeks improves symptoms in patients with CRS. LLLT is one of the most cost-efficient and painless treatment methods for pediatric rhino-sinusitis.

BACKGROUND Bovine colostrums is the milk secreted by cows during the first few days after parturition. It contains many essential nutrients and bioactive components, including growth factors, immunoglobulins, lactoperoxidase, lactoferrin and cytokines ets. Lactoferrin has been reported for its multifunctional properties such as antifungal, antibacterial, antiviral antioxidant and anticancer activities. The aims of this study focused on the isolation and purification of lactoferrin from Mongolian bovine colostrums. Lactoferrin purified using HiTrap DEAE an ion exchange chromatography. Lactoferrin purification efficiency was about 60.5%. The single band of purified lactoferrin has been observed in SDS-PAGE electrophoresis. METHODS Bovine colostrum was collected at a cow farm in the Darkhan province of Mongolia. At first the cream was separated by centrifugation (10000 xg 20 min at 4oC). In order to separate the whey, the samples were precipitated with 1mol/l to pH 4.6 and centrifuged at 10000 g 20 min again. The samples of whey were stored at -18oC to the analysis. Lactoferrin was purified by HiTrap DEAE an ion exchange chromatography using 0.005 M phosphate buffer (pH 7.7) and linear gradient NaCl from 0.25M, 0.5M, 1M. During chromatography, protein in the eluents was monitored by ultraviolet absorbation at 280 nm with the instrument. Purity test done by using polyacrylamide gel electrophoresis under denaturated condition (SDS-PAGE) method by Laemmli (1970). For HPLC determination of the lactoferrin by Shimadzu Nexera X2 HPLC system with UV/ VIS detector were used. Detection was carried out at the wavelength 280 nm. Separation was performed on a chromatographic column Protein R C18 ,2.2 x 150 mm, 5 μm particle size. Linear gradient and flow rate 0.2 ml/min were used. Mobile phase a consisted of water / acetonitrile/ trifluoroacetic acid ( 95:5:0.1). The column temperature was set at 40oC and injection volume was 10 μl. Data were collected and evaluated by software Lab Solution. An external standard method for quantification analytes was used. RESULTS Purified lactoferrin in the present study had a good concentration and purification efficiency was about 60.5 %. Protein fraction from 1M NaCl gradient delivers sharp and clean peak to HPLC chromatogram that fits intensity and retention time of standard bovine lactoferrin. Ammount of lactoferrin in bovine colostrums was 0.6 mg/ml and it`s molecular weight 80 kDa as a standard sample. The retention time of lactoferrin fraction which is purified by SDS-PAGE gel electrophoresis. The peak of fraction same compared to the standard lactoferrin 5.8 minutes by HPLC analysis. CONCLUSION Ion exchange chromatography shows reliable and easy isolation of lactoferrin from Mongol bovine colostrum.

BACKGROUND: The goal is to lower overall health care costs by improving health status among individuals and communities. To become all the people healthier, good health human resource management is critically necessary. METHODS: This research work was done with document research method and got all the necessary information from databases of Public Health development center, Mongolian national statistic agency, Ministry of Health and Ministry of Education Culture and Science. The Statistic processing took on Excel 10 and Stata 14 programs. RESULTS: The exact population of Mongolia is 3.119.935 in 2016. To compare the population spread through the country, Ulaanbaatar, capital city, has the highest density of population. The number of the hospitals and doctors was enough. Actually it was lower than world standard (500 patients per a doctor). Even the number of the doctors are enough, in remote area, it is not enough. In the whole country there are 309 patients per doctor, 237 patients per doctor in Ulaanbaatar and 433 patients per doctor in isolated areas. In conclusion, the human resource distribution is not even in the public health care. CONCLUSION: There are 32.4 chief doctors, 37.2 nurses and, 24 other health employees are assigned to work for 10000 people from the study of 2016. Comparing this study with the previous year’s study, the number of the doctors has gone up by 0.8, but the number of the nurses has gone down by 0.3. Due to the world health organization statistic, the number of the patients per doctor is considered to be low.

BACKGROUND: Bladder cancer is a cancer of significant morbidity and mortality in the worldwide. It is the second most common urological cancer in Mongolia. It is important to understand the risk factors of bladder cancer.We evaluated the association of smoking, alcohol intake, body mass index and other potential risk factors with bladder cancer incidence in Mongolians.MATERIALS AND METHODS: We analyzed data from a case-control study (116 histologically confirmed bladder cancer cases and 300 cancer-free healthy, age, gender-matched controls). All participants signed the consent form andfilled out the structured questionnaire including cigarette smoking, BMI, chronic urinary disease andalcohol drinking etc. Using logistic regression we estimated the covariate-adjusted odds ratio (OR) and95% confidence interval (CI) of the associations.RESULTS: Mean age of the patients with bladder cancer was 56±10.5 years and 79.3% male and 20.7% female.Cigarette smoking, history of urinary tract diseases and body mass index were associated with an increased risk of bladder cancer OR 6, 48 (95% CI 1, 61-1, 70), OR 80 (95% CI 1, 48-1, 93) and OR=9.8 (95% CI 2.32-2.91) respectively but not alcohol drinking OR 0, 26 (95% CI 1, 56-1, 66).CONCLUSIONS: The results suggest that cigarette smoking, history of urinary tract diseases and body mass indexincreased risk of bladder cancer in Mongolian patients.

Background: Many industrialized countries are witnessing a demographic evolution characterized by the aging of their population. For people over aged 65 year, the prevalence of tooth decay, gum disease and oral cancer is higher than for the general population and higher rates for edentulism (missing teeth), few sound teeth and more filled and decayed teeth than the general population. Risk factors for oral diseases include unhealthy diet, tobacco use, harmful alcohol use, and poor oral hygiene. There is no research work concerning the oral health status of the older population aged 65-74 years old. These age group is selected because they were the adult population groups recommended by the WHO for oral health survey. The purpose of this study was to determine prevalence of caries and edentulous of 65-74 years old and living in the Ulanbator. Methods: An epidemiological survey of 365 older people aged 65-74 was carried out in 2008. It followed the WHO methodology to assessing the oral health status and caries lesions, fi llings, missing teeth were recorded using the WHO criteria. Result: The mean age was 68.70.16. The DMFT index at 65-74 years for the Ulanbator population was 19.50.89 DMFT. Caries prevalence was 52.7% among older people. 4.1% were fully dentate, 21.6% were edentulous, 74.2% were partial edentulism, respectively. Mean number of decayed teeth (DT index) was 3.4, fi lling teeth (FT index) was 2.3, missing teeth (MT index) was 18.0. Conclusion: We carried out this study 365 older people aged 65-74. This preliminary study provide evidence in the direction of building the base of knowledge on prevalence of caries and edentulous elderly person in Ulanbator. The planning and implementation of any strategy for oral health status improvement is crucial alongside the countrys infrastructure development.

Objective: The purpose of this study was to establish oral health status among disabled children aged 6-12 years in 6 special schools in Ulaanbaatar. Methods: 428 children with disabilities (cerebral palsy, Down syndrome, mental retardation, blind and hearing disorders) participated in this study. Boys were 50.4%, girls were 49.6% and mean age were 9.921.76. Clinical examination was performed by using a dental mirror and revealed the presence of dental caries, missing (extracted) and fi lled teeth. Each tooth was examined and scored based on the WHO standard (WHO, 1997). The periodontal status was evaluated according to CPI (Community Periodontal Index). The oral hygiene was evaluated according to Green-Vermillion method (1964) values. Results: The dental caries prevalence of all disabled children was 88.3% and average dmft values were 5.714.54 in deciduous teeth, 5.733.72 in mixed dentition and 3.142.81 in permanent teeth. The periodontal status of all children was 70% bleeding after probing and 7% calculus deposit. The oral hygiene was 10% good, 37% fair and 53% poor. Conclusion: This study showed high caries prevalence and DMFT, dmft index and periodontal disease. The oral hygiene index was poor among disabled children in Ulaanbaatar comparing to general population. The main component of DMFT and dmft was decayed teeth, which suggest special oral health promotion policy and urgent treatment, diagnosis and special dental care.