Background: Over the past decade, silver nanoparticles (AgNPs) have gained considerable attention in biomedical research due to their unique physicochemical properties and intrinsic biological activity. Their nanoscale dimensions, high surface-to-volume ratio, and tunable surface chemistry make them promising candidates for advanced drug delivery applications. AgNP-based systems provide a versatile platform for controlled and site-specific drug release, thereby enhancing therapeutic efficacy while minimizing systemic side effects. This review article summarizes the properties of zeolites enhanced with silver nanoparticles (AgNPs). Drug delivery systems incorporating AgNPs operate through both passive and active targeting mechanisms to transport therapeutic agents, including antibiotics, anti-inflammatory drugs, and anticancer compounds, to specific tissues or pathological sites. The performance of these systems is largely governed by the physicochemical characteristics of AgNPs, such as particle size, morphology, surface charge, stability, and surface functionalization. Surface modification enables improved biocompatibility, enhanced drug loading capacity, and controlled release kinetics. Furthermore, the inherent antibacterial activity of AgNPs contributes synergistically to therapeutic outcomes, particularly in the treatment of infected wounds and biofilm-associated infections. Materials and Methods: This review article was prepared by selecting and analyzing relevant publications indexed in Scopus and Web of Science published between 2005 and 2025, focusing on characteristics of AgNPs, drug delivery systems based on zeolites modified with AgNPs and their applications. Conclusion Silver nanoparticle-based drug delivery systems represent an advanced and multifunctional therapeutic platform. Their capacity for targeted, sustained, and controlled drug release, combined with intrinsic antimicrobial activity, offers significant advantages over conventional delivery systems. These properties position AgNPs as promising materials for the development of next-generation biomedical and pharmaceutical applications.

Background: The genus Thalictrum belongs to the family Ranunculaceae Juss. and comprises approximately 200 species distributed worldwide. Most species occur in temperate regions, although a few are also found in lowland areas. Approximately 43 species of Thalictrum have traditionally been used as medicinal raw materials due to their notable therapeutic properties and reported efficacy. These plants have traditionally been used to treat a wide range of conditions, including infectious diseases, nervous system disorders, joint diseases, intestinal inflammation, gingivitis, tumors, jaundice, pneumonia, and other pulmonary inflammatory conditions. They have also been used for wound healing, reducing fever, treating gastric and duodenal ulcers, managing eye disorders and headaches, restoring physical strength, promoting diuresis, alleviating digestive disturbances, stimulating intestinal peristalsis to facilitate bowel movements, supporting recovery after illness, and treating snakebites. Phytochemical investigations have revealed that Thalictrum species contain diverse bioactive constituents, including alkaloids, flavonoids, glycosides, terpenoids, fatty acids, and phenolic compounds. These compounds have been associated with various pharmacological properties, particularly antioxidant, anti-inflammatory, antimicrobial, cytotoxic, and antitumor activities. Therefore, Thalictrum minus, a species that is widely distributed in Mongolia but whose chemical composition and biological activities have not yet been comprehensively investigated, was selected for the present study. Aim: To determine total phenolic and flavonoid content of crude extracts of this plant. To investigate the antioxidant activity. Materials and Methods: Total phenolic compounds, total flavonoids and antioxidant activity were determined using spectrophotometer methods using extracts from the aerial parts of T. minus. Dried flowering plant material of Thalictrum minus, taxonomically identified by the Botanical Garden of the Mongolian Academy of Sciences, was obtained from the Department of Pharmaceutical Technology, Mongolian University of Pharmaceutical Sciences. Total phenolic content (TPC) was determined using the Folin–Ciocalteu method, with gallic acid as the reference standard, and absorbance was measured at 760 nm. Total flavonoid content (TFC) was determined using an aluminum chloride colorimetric assay, with rutin as the reference standard, and absorbance was measured at 500 nm. Antioxidant activity was evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical-scavenging assay. Plant extracts at different concentrations were mixed with DPPH solution and incubated in the dark for 30 min. Absorbance was measured at 517 nm using an Agilent BioTek Epoch 2 microplate reader, with quercetin as the positive control. Radical-scavenging activity was calculated as a percentage, and IC₅₀ values were determined from concentration–response curves. All measurements were performed in triplicate or quadruplicate, and results were expressed as IC₅₀±standard deviation (SD). Results: The total phenolic, total flavonoid content and antioxidant activity of the aerial parts of T. minus, a plant species growing in Mongolia, were evaluated using spectrophotometric methods. The total phenolic content of the aerial parts of Thalictrum minus L. was determined using gallic acid as the reference standard. The absorbance was measured at 500 nm, and the content was calculated using the calibration equation (y=0.6947x + 0.0046, R²=0.9997), yielding a total phenolic content of 5.38±0.09%. The total flavonoid content was determined using rutin as the reference standard and calculated using the calibration equation (y=0.3089x +0.0112, R²=0.9960), yielding a content of 2.04±0.16%. The antioxidant activity of the aerial-part extract was evaluated using the DPPH free-radical scavenging assay, which yielded an IC₅₀ value of 66.09 µg/mL. Conclusion The contents of selected bioactive secondary metabolites in the aerial parts of Thalictrum minus were determined. In addition, the antioxidant activity of the aerial-part extracts was evaluated in comparison with reference standards, demonstrating that the extracts possess antioxidant activity.

Background: Background: In recent years, ensuring a safe and healthy working environment for mining employees, improving working conditions, protecting and promoting health, and paying attention to other factors affecting health have become essential requirements. While infectious diseases, noncommunicable (chronic) diseases, nutritional disorders, occupational injuries, and mental health conditions are the main indicators for assessing the health impact on mining workers, there is still a lack of research on noncommunicable diseases among mining sector employees in Mongolia. This gap served as the basis for the present study. Aim: To study the risk factors of noncommunicable diseases among employees of Erdenet Mining Corporation Materials and Methods: A total of 303 employees from 15 divisions of Erdenet Mining Corporation participated in the study. Participants belonging to high-risk groups for noncommunicable diseases were selected using a purposive sampling method. The survey questionnaire was developed based on the WHO STEP wise approach to Surveillance (STEPS) of noncommunicable disease risk factors. Results: Of all participants, 70% were male and 30% were female, with an average age of 46 years. The average total duration of employment was 23 years, of which male employees had worked an average of 19.3 years and female employees 17.3 years at Erdenet Mining Corporation. Among participants, 48.5% had never smoked, while 38.3% were current smokers. When analyzing alcohol consumption by job position, it was found that 85.7% of managers and 66.7% of administrative and decoration workers had high levels of alcohol consumption. Regarding physical activity, 23% of male and 15.2% of female employees reported engaging in active exercise more than three days per week, indicating that male employees were more physically active than females. In terms of dietary habits, 28.3% of males and 17.6% of females did not control their salt intake. As for eating patterns, 53.6% of employees regularly had breakfast, 77.3% regularly had lunch, and 76.6% regularly had dinner at a fixed time. Conclusions 1. Among the employees surveyed, 48.5% had never smoked, while 38.3% were current smokers. Daily smoking was most prevalent among employees aged 35–54 years (74.2%), with the 25–34 age group also showing a relatively high rate of smoking. Regarding alcohol consumption, 38.2% of male employees reported drinking vodka or similar alcoholic beverages. Alcohol consumption was significantly higher among males compared to females, indicating that it is a major risk factor for noncommunicable diseases (p=0.003). 2. In terms of dietary patterns, 53.6% of employees reported regularly having breakfast, 77.3% regularly had lunch, and 76.6% regularly had dinner. Eating habits varied by gender. Concerning physical activity, 23% of male employees and 15.2% of female employees engaged in regular exercise, indicating that male employees were more physically active than females. The study found that lifestyle and behavioral factors such as smoking, alcohol consumption, insufficient physical activity, and poor dietary habits contribute to an increased risk of noncommunicable diseases among employees.

Background: Researchers have identified that occupational exposures related to mining operations-such as dust, noise, and vibration—can increase the risk of developing occupational diseases, including pneumoconiosis, hearing loss, and spinal injuries, as well as noncommunicable conditions such as hypertension and cardiovascular diseases. Work-related stress, living away from family, reliance on portable food services, and shift work systems also contribute to weight gain and negatively affect endocrine function. Aim: To investigate the prevalence of metabolic syndrome and noncommunicable diseases among employees of Erdenet Mining Corporation Materials and methods: A total of 303 employees from 15 divisions of Erdenet Mining Corporation participated in the study. Participants included employees with 10–20 years or more of service; 15% were female, and 75% were technical workers. Employees belonging to high-risk groups for noncommunicable diseases were selected using a purposive sampling method. Results: When analyzing body mass index (BMI) by occupation, overweight or obesity was found among 79.2% of service workers, 65% of electricians, 100% of fuel distributors, 77.8% of decorators, 75.5% of mechanics, 94.7% of specialists, 86.4% of professional workers, 75.7% of operators and engineers, and 88.9% of administrative staff. Central obesity was also analyzed by job position, revealing that 79.2% of service workers, 60% of laboratory staff, 35% of electricians, 64.9% of operators and engineers, and 66.7% of administrative employees had central obesity. Among all participants, 20.7% had a previous history of cardiovascular disease, of whom 71.4% were male and 28.6% were female. The mean blood glucose level among participants was 6.0 mmol/L, with a median of 5.6 mmol/L, a minimum of 3.9 mmol/L, and a maximum of 18.3 mmol/L. The median glucose level was 0.2 mmol/L lower than the national average. No statistically significant difference in blood glucose levels was found between males and females (p = 0.135). By job position, elevated blood glucose levels (prediabetic range) were found in 62.5% of service workers, 40% of laboratory staff, 35% of electricians, 71.4% of managers, and 55.6% of administrative employees. Conclusion The findings indicate an increasing trend in metabolic and cardiovascular risk factors among employees of Erdenet Mining Corporation SOE.