1.Tension-free vaginal tape-Abbrevo procedure for female stress urinary incontinence: a prospective analysis over 22 months.
Alice KURIEN ; Sarita NARANG ; How Chuan HAN
Singapore medical journal 2017;58(6):338-342
INTRODUCTIONWe aimed to study the efficacy and safety of the tension-free vaginal tape (TVT)-Abbrevo procedure for female stress urinary incontinence (SUI).
METHODSThis was a prospective cohort study that aimed to determine the subjective and objective cure, improvement of SUI and incidence of complications among women who underwent TVT-Abbrevo for SUI during a period of 22 months from September 2011 to June 2013.
RESULTSA total of 76 patients, with a mean age of 48.2 ± 8.1 years, underwent TVT-Abbrevo during the study period. Among them, 86.8% had vaginal delivery and 5.3% had instrumental delivery. Mean parity was 2.3 ± 0.8 and mean body mass index was 27.0 ± 5.0 kg/m. 11 (14.5%) patients had previously tried physiotherapy. Mean follow-up duration was 12.3 ± 5.6 months. The subjective cure rate for SUI at one-month, six-month and one-year follow-up was 95.7%, 90.8%, and 90.6%, respectively. Among the nine patients who completed the two-year follow-up, 88.9% reported either cure or improvement of SUI. At six months, the proportion of patients with objective cure was 86.8%, and the rates of postoperative groin pain and complications were low. In addition, overactive bladder symptoms disappeared in 76.3% of patients.
CONCLUSIONOur results are comparable with those of other studies, although long-term results remain to be seen.
2.Uterine sarcomas in RIPAS Hospital, Brunei Darussalam: A 10-year Experience
Alice Kurien ; Saw Ohnmar ; Roselina Yaakub
Brunei International Medical Journal 2012;8(5):231-236
Introduction: Uterine sarcomas are rare but aggressive malignant tumours of the smooth muscle or
supporting tissues of the uterus. Currently, there are no published data available in Brunei Darussalam.
This study was done to evaluate the demographic profile, risk factors, diagnostic issues and the clinical
outcome of patients with uterine sarcomas in the Raja Isteri Pengiran Anak Saleha (RIPAS) hospital, a
tertiary hospital in Brunei Darussalam. Patients and Methods: All patients with uterine sarcoma reg-
istered in the Department of Obstetrics and Gynaecology during a period of ten years (2001 to 2010)
were studied. Cases were identified through the Gynaecology Oncology registry and the case notes
were retrospectively reviewed. Results: Over this period, there were 156 cases of uterine tumour and
of these, 37 cases (23.7%) were uterine sarcoma. The majority were local (n=34, Bruneian 81.1%; 30
Malays and four Chinese) with a mean age of 47.8 years. High risk factors were identified in 29
(78.4%) patients. Abnormal uterine bleeding and mass per abdomen were the most common clinical
presentations. A preoperative diagnosis was possible only in five cases (13.5%) and in two patients
(5.4%) the diagnosis was suspected during surgery and confirmed by frozen section. At the completion
of a five-year follow up in the first five year group (2001 to 2005) 62.5% patients are alive and disease
free. There were six deaths from the disease during the entire study period. Conclusion: A high pro-
portion of uterine tumours were uterine sarcoma. The majority of the patients (78.4%) had one or
more risk factors. Unlike endometrial carcinoma a preoperative diagnosis is difficult in uterine sarcoma.
At the time of this study 70.3% of patients with uterine sarcoma were alive and disease free.

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