Objectives:To explore the trend of the burden of cardiovascular disease (CVD) in adult Chinese population attributed to high body mass index (BMI) from 1990 to 2021,identify key populations requiring for BMI control,and provide scientific evidence for developing targeted intervention strategies.Methods:Based on the Global Burden of Disease (GBD) 2021 database,we compared the age-standardized disability-adjusted life years (DALY) rates and age-standardized mortality rates of CVD attributed to high BMI for the adult population aged ≥20 years in China,globally,and in the United States,the United Kingdom,Japan,and India from 1990 to 2021.Additionally,the results were stratified by sex and age to compare the trends of disease burden in China and globally.Results:From 1990 to 2021,the average annual percentage change (AAPC) in age-standardized DALY rate and age-standardized mortality rate for CVD attributable to high BMI for the population aged ≥20 years in China was 1.08 (95％CI:1.05 to 1.11) and 1.00 (95％CI:0.96 to 1.03),respectively.Throughout the 32-year period,both rates were consistently lower than those in the United States and the global average,but higher than those in India and Japan.Meanwhile,England experienced a continuous decline,with corresponding data of-3.02 (95％CI:-3.10 to-2.96) for AAPC in age-standardized DALY rates and-3.02 (95％CI:-3.11 to-2.95) for AAPC in age-standardized mortality rates,respectively.The age-standardized DALY rate attributed to high BMI for adult males in China was consistently higher than those for females,whereas the percentage of DALY showed the opposite trend,with females surpassing males.The age-standardized DALY rates for the population aged ≥20 years attributed to high BMI in China increased continuously,and the percentage of DALY increased sharply in population aged 20-39,the level of 2021 was more than three times higher as compared to 1990.Conclusions:The increasing proportion of overweight and obese individuals in China,along with the resulting rise in the prevalence and mortality of cardiovascular diseases,has led to a continuous increase in the cardiovascular disease burden.It is therefore particularly important to implement effective public health interventions to control overweight in the young and middle-aged population to reduce the burden of cardiovascular disease in China.

Objectives:To explore the trend of the burden of cardiovascular disease (CVD) in adult Chinese population attributed to high body mass index (BMI) from 1990 to 2021,identify key populations requiring for BMI control,and provide scientific evidence for developing targeted intervention strategies.Methods:Based on the Global Burden of Disease (GBD) 2021 database,we compared the age-standardized disability-adjusted life years (DALY) rates and age-standardized mortality rates of CVD attributed to high BMI for the adult population aged ≥20 years in China,globally,and in the United States,the United Kingdom,Japan,and India from 1990 to 2021.Additionally,the results were stratified by sex and age to compare the trends of disease burden in China and globally.Results:From 1990 to 2021,the average annual percentage change (AAPC) in age-standardized DALY rate and age-standardized mortality rate for CVD attributable to high BMI for the population aged ≥20 years in China was 1.08 (95％CI:1.05 to 1.11) and 1.00 (95％CI:0.96 to 1.03),respectively.Throughout the 32-year period,both rates were consistently lower than those in the United States and the global average,but higher than those in India and Japan.Meanwhile,England experienced a continuous decline,with corresponding data of-3.02 (95％CI:-3.10 to-2.96) for AAPC in age-standardized DALY rates and-3.02 (95％CI:-3.11 to-2.95) for AAPC in age-standardized mortality rates,respectively.The age-standardized DALY rate attributed to high BMI for adult males in China was consistently higher than those for females,whereas the percentage of DALY showed the opposite trend,with females surpassing males.The age-standardized DALY rates for the population aged ≥20 years attributed to high BMI in China increased continuously,and the percentage of DALY increased sharply in population aged 20-39,the level of 2021 was more than three times higher as compared to 1990.Conclusions:The increasing proportion of overweight and obese individuals in China,along with the resulting rise in the prevalence and mortality of cardiovascular diseases,has led to a continuous increase in the cardiovascular disease burden.It is therefore particularly important to implement effective public health interventions to control overweight in the young and middle-aged population to reduce the burden of cardiovascular disease in China.