1.Design and Efficacy Evaluation of Steam Thermal Ablation System for Liver Tumor.
Wei WEI ; Xiaofei JIN ; Lidong XING ; Zhiyu QIAN ; Haotian WANG ; Jingqi SONG ; Kairan WAN
Chinese Journal of Medical Instrumentation 2025;49(3):323-329
To address the limitations of traditional minimally invasive thermal ablation technology such as poor conformability, carbonization and electromagnetic radiation, this paper proposes a steam thermal ablation technology that uses saturated steam internal energy to replace the traditional electromagnetic radiation energy. Through the steam thermal ablation system and the steam thermal ablation needle designed based on simulation, the ex vivo pig liver experiments were carried out. The results have the characteristics of the maximum ablation axis ratio (short diameter / long diameter) and non-carbonization with the same type of thermal ablation technology. Based on the near-infrared light, in this paper the curative effect of the reduced scattering coefficient of the steam thermal ablation results was evaluated. The reduced scattering coefficients of the coagulation area all exceeded 16, reaching the completely damaged state, which verified that the steam thermal ablation can effectively inactivate the tumor cells.
Steam
;
Animals
;
Swine
;
Liver Neoplasms/surgery*
;
Ablation Techniques/methods*
;
Liver/surgery*
;
Equipment Design
2.Chinese expert consensus on MRI-guided thermal ablation for liver tumors (2025 edition).
Chinese Journal of Internal Medicine 2025;64(11):1084-1095
Image-guided thermal ablation (IGTA) has been widely used in the treatment of liver tumors. MRI-guided thermal ablation of liver tumors offers several advantages, including the absence of ionizing radiation; excellent soft-tissue contrast; multi-parametric and multiplanar imaging; non-invasive, real-time temperature monitoring of the thermal field during the procedure; and accurate post-procedural assessment of therapeutic efficacy. To standardize and promote MRI-guided thermal ablation for liver tumors in China, advance the technological development of IGTA for tumor treatment, and enhance the efficacy of "precision ablation" for hepatic tumors, this expert consensus (2025 edition) was collaboratively developed by national experts from multiple societies and committees through multidisciplinary discussions. The contributing groups included the Society of Tumor Ablation Therapy of the Chinese Anti-Cancer Association, the Ablation Expert Committee of the Chinese Society of Clinical Oncology (CSCO), the Tumor Ablation Subgroup of the National Health Commission Comprehensive Interventional Therapy Quality Control Center, the Expert Group on Tumor Ablation Therapy of the Chinese Medical Doctors Association, and the Tumor Ablation Committee of the Chinese College of Interventionalists. The main contents of the consensus include: (1) indications, contraindications, and characteristics of MRI-guided thermal ablation for liver tumors; (2) MRI magnets, guidance sequences, and MRI-compatible thermal ablation equipment and instruments; and (3) protocols for MRI-guided thermal ablation of liver tumors, efficacy assessment, and the prevention and management of complications.
Humans
;
Liver Neoplasms/surgery*
;
Magnetic Resonance Imaging
;
Consensus
;
China
;
Catheter Ablation/methods*
;
Ablation Techniques/methods*
;
Surgery, Computer-Assisted
3.Expert Consensus for Image-guided Radiofrequency Ablation of Pulmonary Tumors (2018 Version).
Baodong LIU ; Xin YE ; Weijun FAN ; Xiaoguang LI ; Weijian FENG ; Qiang LU ; Yu MAO ; Zhengyu LIN ; Lu LI ; Yiping ZHUANG ; Xudong NI ; Jialin SHEN ; Yili FU ; Jianjun HAN ; Chenrui LI ; Chen LIU ; Wuwei YANG ; Zhiyong SU ; Zhiyuan WU ; Lei LIU
Chinese Journal of Lung Cancer 2018;21(2):76-88
4.Iodine 131 joint radio frequency ablation treatment for child with hyperthyroidism goiter: one case report.
Yonghua CHEN ; Li LIANG ; Yanlan FANG ; Chunlin WANG ; Linfa LI ; Tian'an JIANG
Journal of Zhejiang University. Medical sciences 2017;46(1):89-91
A 12-year-old girl presented with a history of cervical mass, and one week of throat discomfort and dyspnea. Five years ago, the patient was diagnosed as Hashimoto's thyroiditis and hyperthyroidism; she received antithyroid drug treatment, but the result was not satisfactory. B-ultrasonic showed that the size of thyroid gland was 8.1 cm×3.2 cm in the left and 8.2 cm×4.8 cm in the right. After iodine 131 combined with radiofrequency ablation (RFA) treatment, throat discomfort and recumbent breathing difficulties disappeared, and B-ultrasonic showed that the size of thyroid reduced to 2.3 cm×1.7 cm (left) and 2.8 cm×2.0 cm (right). No recurrence was observed during the two and a half years of follow-up.
Ablation Techniques
;
methods
;
Child
;
Dyspnea
;
etiology
;
therapy
;
Female
;
Goiter
;
complications
;
diagnostic imaging
;
pathology
;
therapy
;
Hashimoto Disease
;
therapy
;
Humans
;
Hyperthyroidism
;
therapy
;
Iodine Radioisotopes
;
therapeutic use
;
Radio Waves
;
therapeutic use
;
Ultrasonography
5.Local Atrial/Ventricular Ratio as an Adjuvant Marker for Catheter Ablation of Atrioventricular Accessory Pathways.
Ki Hun KIM ; Dae Kyeong KIM ; Hyun Ji IM ; Jeong Sook SEO ; Han Young JIN ; Jae Sik JANG ; Tae Hyun YANG ; Dong Soo KIM ; So Young JEONG ; Yun Seok SONG ; Dong Kie KIM ; Pil Sang SONG ; Sang Hoon SEOL ; Doo IL KIM
Korean Circulation Journal 2017;47(4):462-468
BACKGROUND AND OBJECTIVES: The earliest atrial (A)/ventricular (V) activation potential, or accessory pathway (AP) potential are commonly used as ablation targets for atrioventricular (AV) APs. However, these targets are sometimes ambiguous. SUBJECTS AND METHODS: We reviewed 119 catheter ablation cases in 112 patients diagnosed with orthodromic atrioventricular reentrant tachycardia (AVRT) or Wolff-Parkinson-White (WPW) syndrome. Local A/V amplitude potentials with the earliest activation or AP potential were measured shortly before achieving antegrade AP conduction block, ventriculoatrial block during right ventricle (RV) pacing, or AVRT termination with no AP conduction. RESULTS: APs were located in the left lateral (55.5%), left posterior (17.6%), left posteroseptal (10.1%), midseptal (1.7%), right posteroseptal (7.6%), right posterior (1.7%), and right lateral (5.9%) regions. The mean earliest activation time was 16.7±15.5 ms, mean A/V potential was 1.1±0.9/1.0±0.9 mV, and mean A/V ratio was 1.7±2.0. There was no statistically significant difference between the activation methods (antegrade vs. RV pacing vs. orthodromic AVRT) or AP locations (left vs. right atrium). However, when the local A/V ratio was divided into 3 groups (≤0.6, 1.0±0.3, and ≥1.4), the antegrade approach resulted in an A/V ratio greater than 1.0±0.3 (86.7%, p=0.007), and the orthodromic AVRT state resulted in a ratio of less than 1.0±0.3 (87.5%, p<0.001). CONCLUSION: The mean local A/V potential and ratio did not differ by activation method or AP location. However, a different A/V ratio based on activation method (≥1.0±0.3, antegrade approach; and ≤1.0±0.3, orthodromic AVRT state) could be a good adjuvant marker for targeting AV APs.
Catheter Ablation*
;
Catheters*
;
Electrophysiologic Techniques, Cardiac
;
Heart Ventricles
;
Humans
;
Methods
;
Tachycardia
;
Tachycardia, Supraventricular
6.The key points of prevention for special surgical complications after radical operation of gastric cancer.
Hao XU ; Weizhi WANG ; Panyuan LI ; Diancai ZHANG ; Li YANG ; Zekuan XU
Chinese Journal of Gastrointestinal Surgery 2017;20(2):152-155
Incidence of gastric cancer is high in China and standard radical operation is currently the main treatment for gastric cancer. Postoperative complications, especially some special complications, can directly affect the prognosis of patients, even result in the increase of mortality. But the incidences of these special complications are low, so these complications are often misdiagnosed and delayed in treatment owing to insufficient recognition of medical staff. These special complications include (1) Peterson hernia: It is an abdominal hernia developed in the space between Roux loop and transverse colon mesentery after Roux-Y reconstruction of digestive tract. Peterson hernia is rare and can quickly result in gangrenous ileus. Because of low incidence and without specific clinical symptoms, this hernia does not attract enough attention in clinical practice, so the outcome will be very serious. Once the diagnosis is made, an emergent operation must be performed immediately. Peterson space should be closed routinely in order to avoid the development of hernia. (2) Lymphatic leakage: It is also called chyle leakage. Cisterna chylus is formed by gradual concentration of extensive lymphatic net to diaphragm angle within abdominal cavity. Lymphadenectomy during operation may easily damage lymphatic net and result in leakage. The use of ultrasonic scalpel can decrease the risk of lymphatic leakage in certain degree. If lymphatic leakage is found during operation, transfixion should be performed in time. Treatment includes total parenteral nutrition, maintenance of internal environment, supplement of protein, and observation by clamp as an attempt. (3)Duodenal stump leakage: It is one of serious complications affecting the recovery and leading to death after subtotal gastrectomy. Correct management of duodenal stump during operation is one of key points of the prevention of duodenal stump leakage. Routine purse embedding of duodenal stump is recommend during operation. The key treatment of this complication is to promt diagnosis and effective hemostasis.(4) Blood supply disorder of Roux-Y intestinal loop: Main preventive principle of this complication is to pay attention to the blood supply of vascular arch in intestinal edge. (5) Anastomotic obstruction by big purse of jejunal stump: When Roux-en-Y anastomosis is performed after distal radical operation for gastric cancer, anvil is placed in the remnant stomach and anastomat from distal jejunal stump is placed to make gastrojejunal anastomosis, and the stump is closed with big purse embedding. The embedding jejunal stump may enter gastric cavity leading to internal hernia and anastomotic obstruction. We suggest that application of interruptable and interlocking suture and fixation of stump on the gastric wall can avoid the development of this complication.
Anastomosis, Roux-en-Y
;
adverse effects
;
China
;
Chylous Ascites
;
etiology
;
prevention & control
;
therapy
;
Duodenum
;
blood supply
;
surgery
;
Gastrectomy
;
adverse effects
;
methods
;
mortality
;
Gastric Outlet Obstruction
;
etiology
;
prevention & control
;
Gastric Stump
;
surgery
;
Hemostatic Techniques
;
Hernia
;
etiology
;
prevention & control
;
therapy
;
High-Intensity Focused Ultrasound Ablation
;
instrumentation
;
Humans
;
Jejunum
;
blood supply
;
surgery
;
Lymph Node Excision
;
adverse effects
;
instrumentation
;
Lymphatic System
;
injuries
;
Postoperative Complications
;
classification
;
diagnosis
;
mortality
;
prevention & control
;
Prognosis
;
Stomach
;
surgery
;
Stomach Neoplasms
;
complications
;
surgery
;
Suture Techniques
;
standards
;
Thoracic Duct
;
injuries
;
Wound Closure Techniques
;
standards
7.A Single-institution Experience with Open Irreversible Electroporation for Locally Advanced Pancreatic Carcinoma.
Li YAN ; Yong-Liang CHEN ; Ming SU ; Tian LIU ; Kai XU ; Feng LIANG ; Wan-Qing GU ; Shi-Chun LU
Chinese Medical Journal 2016;129(24):2920-2925
BACKGROUNDLocally advanced pancreatic carcinoma (LAPC) is characterized by poor prognosis despite recommended concurrent chemoradiotherapy. Irreversible electroporation (IRE) has emerged as a potential option for the management of unresectable pancreatic cancer. This study was conducted to evaluate the safety and short-term efficacy of open IRE for the treatment of LAPC.
METHODSRetrospective data of 25 consecutive patients receiving IRE for T3 lesions from July 2015 to June 2016 at a single center were analyzed. The perioperative and long-term IRE-related complications were reviewed to evaluate the safety of the procedure. The tumor reduction and biological response were analyzed through computed tomography/magnetic resonance imaging; the serum level of CA19-9 was measured as a secondary endpoint to evaluate the short-term efficacy of IRE.
RESULTSAll patients were successfully treated; the median tumor size was 4.2 cm and the median IRE time was 36 min. Four intraoperative procedure-related complications were observed (16%): two transient hypertensive episodes, one hypotension case, and one transient supraventricular tachycardia case. Nine postoperative complications were described, including three Grade A pancreatic fistulas, three delayed gastric emptying, one acute pancreatitis, one upper gastrointestinal hemorrhage, and one portal vein thrombosis. The overall rate of stable disease was 28%, 36% achieved partial response, and lower serum CA19-9 levels were recorded in all patients at discharge.
CONCLUSIONSIRE is feasible for the treatment of LAPC and is a reasonable intervention strategy owing to its combined attributes of safety and efficacy.
Ablation Techniques ; adverse effects ; methods ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; CA-19-9 Antigen ; blood ; Electroporation ; methods ; Female ; Humans ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Pancreatic Neoplasms ; blood ; pathology ; surgery ; Postoperative Complications ; blood ; pathology ; Retrospective Studies ; Treatment Outcome ; Young Adult
8.Clinical efficacy of NovaSure for 30 patients with adenomyosis.
Dan LI ; Yajun WAN ; Qingling MU
Journal of Central South University(Medical Sciences) 2016;41(1):88-92
OBJECTIVE:
To investigate the efficacy and safety of NovaSure system for dysmenorrhea and abnormal uterine bleeding of adenomyosis.
METHODS:
A retrospective analysis on 30 patients with adenomyosis, who treated by NovaSure, were carried out. We collected related clinical data before operation and collected postoperative information about dyemenorrhea, menstruation, anemia and uterine volume by visiting outpatient or telephone.
RESULTS:
All patients were followed up for 7 to 31 months after the operation. The relief rate of menstrual pain was 83.3%. All patients got obvious improvements in menstruation and anemia (P<0.05). After operation, uterine volume was significantly decreased (P<0.05). Only one case received intervention in 2 years (3.3%).
CONCLUSION
NovaSure can relieve symptoms of menorrhagia and alleviate dysmenorrhea symptoms. It is a new way for the treatment of uterine adenomyosis.
Adenomyosis
;
surgery
;
Dysmenorrhea
;
surgery
;
Endometrial Ablation Techniques
;
methods
;
Female
;
Humans
;
Menorrhagia
;
surgery
;
Retrospective Studies
;
Treatment Outcome
9.Measurement of Intrahepatic Pressure during Microwave Ablation in an Ex Vivo Bovine Liver Model.
Hae Jin KIM ; Hyunchul RHIM ; Min Woo LEE ; Woo Kyoung JEONG
Gut and Liver 2015;9(6):784-790
BACKGROUND/AIMS: We experimented with different ablation methods and two types of microwave antennas to determine whether microwave ablation (MWA) increases intrahepatic pressure and to identify an MWA protocol that avoids increasing intrahepatic pressure. METHODS: MWA was performed using either a single-step standard ablation or a stepwise increment ablation paired with either a 16-gauge (G) 2-cm antenna or a 14G 4-cm antenna. We compared the maximum pressures and total ablation volumes. RESULTS: The mean maximum intrahepatic pressures and ablation volumes were as follows: 16G single-step: 37+/-33.4 mm Hg and 4.63 cm3; 16G multistep: 31+/-18.7 mm Hg and 3.75 cm3; 14G single-step: 114+/-45.4 mm Hg and 15.33 cm3; and 14G multistep: 106+/-43.8 mm Hg and 10.98 cm3. The intrahepatic pressure rose during MWA, but there were no statistically significant differences between the single and multistep methods when the same gauge antennae were used. The total ablation volume was different only in the 14G groups (p<0.05). CONCLUSIONS: We demonstrated an increase in intrahepatic pressure during MWA. The multistep method may be used to prevent increased intrahepatic pressure after applying the proper power.
Ablation Techniques/instrumentation/*methods
;
Animals
;
Cattle
;
Liver/*physiology/surgery
;
Medical Illustration
;
*Microwaves
;
Models, Animal
;
*Pressure
10.Left Atrial Function Following Surgical Ablation of Atrial Fibrillation: Prospective Evaluation Using Dual-Source Cardiac Computed Tomography.
Joon Bum KIM ; Dong Hyun YANG ; Joon Won KANG ; Sung Ho JUNG ; Suk Jung CHOO ; Cheol Hyun CHUNG ; Jae Kwan SONG ; Jae Won LEE
Yonsei Medical Journal 2015;56(3):608-616
PURPOSE: The Maze procedure has shown excellent efficacy in the elimination of atrial fibrillation (AF); however, little is known about the quality of functional recovery in the left atrium (LA) following successful sinus rhythm conversion by the Maze procedure. MATERIALS AND METHODS: We prospectively enrolled 12 patients (aged 52.5+/-10.1 years, 1 female) with valvular AF undergoing mitral valve surgery combined with the Maze procedure. Parameters of LA function in three anatomic compartments [anterior, posterior, and LA appendage (LAA)] were evaluated using electrocardiography-gated dual-source cardiac CT at one month and at six months after surgery. Twelve subjects matched by age, gender, and body surface area served as controls. RESULTS: At one month after surgery, ejection fraction (EF) and emptying volume (EV) of the LA were 14.9+/-7.4% and 21.3+/-9.7 mL, respectively, and they were significantly lower than those of the control group (EF, 47.9+/-11.2%; EV, 46.0+/-10.7%; p<0001). These values did not significantly change throughout late periods (p=0.22 and 0.21, respectively). Functional contributions of the anterior, posterior, and appendage compartments (EV of each compartment/overall EV) were 80.4%, -0.9%, and 20.5%, respectively, for those with LAA preservation (n=6); 100.1%, -0.1%, and 0% for those with LAA resection (n=6; p<0.05); and 62.2%, 28.2%, and 9.7% in the control subjects (p<0.001). CONCLUSION: Contractile functions of the LA significantly decreased after the Maze procedure. Functional contributions of three compartments of the LA were also altered. The influence of LAA preservation on postoperative LA functions needs to be evaluated through studies of larger populations.
*Ablation Techniques
;
Adult
;
Aged
;
Atrial Appendage/*physiopathology
;
Atrial Fibrillation/physiopathology/*surgery
;
Atrial Function, Left/*physiology
;
Case-Control Studies
;
Electrocardiography/methods
;
Female
;
Heart Atria
;
Humans
;
Male
;
Middle Aged
;
Prospective Studies
;
Recovery of Function
;
Tomography, X-Ray Computed

Result Analysis
Print
Save
E-mail