1.The first report of the buckled thyroid cartilage in a human cadaver
Craig BALLARD ; Joe IWANAGA ; Eva MARANILLO ; Jose SANUDO ; Aaron S. DUMONT ; R. Shane TUBBS
Anatomy & Cell Biology 2023;56(2):268-270
We present the first case of buckled thyroid cartilage identified in a human cadaver. This rare anatomical variant, in patients, often produces dysphonia and is a potential source for diagnostic confusion. In the cadaveric case described, the laryngeal prominence is deviated to the left without deviation of the internal structures of the larynx, such as vocal folds and vocalis muscles. The medical history of the patient is not known. Finally, a review of current literature on the buckled thyroid cartilage is presented. Such a case represents a rare opportunity to visualize this deformity via anatomical dissection.
2.An unusual arrangement between the highest denticulate ligament and posterior inferior cerebellar artery
Aditi PATEL ; Johnathan BAUDOIN ; Arada CHAIYAMOON ; Juan J. CARDONA ; Ana CARRERA ; Francisco REINA ; Joe IWANAGA ; Aaron S. DUMONT ; R. Shane TUBBS
Anatomy & Cell Biology 2023;56(3):394-397
The posterior inferior cerebellar artery (PICA) is often involved in pathologies of the posterior cranial fossa. Therefore, a good understanding of the vessel’s normal and variant courses is important to the neurosurgeon or neurointerventionalist. During the routine microdissection of the craniocervical junction, an unusual arrangement between the highest denticulate ligament and PICA was observed. On the right side, the PICA was given rise to by the V4 segment of the vertebral artery 9 mm after the artery entered the dura mater of the posterior cranial fossa. The artery made an acute turn around the lateral edge of the highest denticulate ligament to then recur 180 degrees and travel medially toward the brainstem. Invasive procedures that target the PICA should be aware of the variant as described herein.
3.Innervation of pineal gland by the nervus conarii: a review of this almost forgotten structure
Kion GREGORY ; Tyler WARNER ; Juan J. CARDONA ; Arada CHAIYAMOON ; Joe IWANAGA ; Aaron S. DUMONT ; R. Shane TUBBS
Anatomy & Cell Biology 2023;56(3):304-307
The nervus conarii provides sympathetic nerve innervation to the pineal gland, which is thought to be the primary type of stimulus to this gland. This underreported nerve has been mostly studied in animals. One function of the nervus conarii may be to activate pinealocytes to produce melatonin. Others have also found substance P and calcitonin gene-related peptide from the nervus conarii ending in the pineal gland. The following paper reviews the extant medical literature on the nervus conarii including its anatomy and potential function.
4.The laryngopharyngeal nerve: a comprehensive review
Stephen SHAPIRO ; Andrew L. PARKER ; Juan J. CARDONA ; Arada CHAIYAMOON ; Francisco REINA ; Ana CARRERA ; Joe IWANAGA ; Aaron S. DUMONT ; R. Shane TUBBS
Anatomy & Cell Biology 2023;56(3):299-303
The laryngopharyngeal nerve has received much less attention that the other contributions to the pharyngeal plexus i.e., glossopharyngeal and vagus nerves. Often, in descriptions and depictions, the nerve is simply labeled as the sympathetic contribution to the pharyngeal plexus. As there is such scant information available regarding this nerve, the present review was performed. Very little is found in the extant medical literature regarding the laryngopharyngeal nerve. However, based on available data, the nerve is a consistent contributory to the pharyngeal plexus and serves other adjacent areas e.g., carotid body. Therefore, a better understanding of this structure’s anatomy is important for those who operate in this area. Further studies are necessary to better elucidate the true function of the laryngopharyngeal nerve.
5.Duplication of the ovarian vein: comprehensive review and case illustration
Edward C. MUO ; Joe IWANAGA ; Łukasz OLEWNIK ; Aaron S. DUMONT ; R. Shane TUBBS
Anatomy & Cell Biology 2022;55(2):251-254
Variations of the ovarian veins can impact imaging diagnosis, surgical procedures of the region, and can be related to clinical findings such as compression of the ureter. Therefore, a good working knowledge of such variants is important to the clinician who interprets imaging of the posterior abdominopelvic region of women and surgeons who operate in this region. Herein, we present a comprehensive review of duplicated ovarian veins and provide a case illustration.
6.Three ipsilateral paracondylar processes with other skull base variations: case report
Annie SYED ; Łukasz OLEWNIK ; Georgi P. GEORGIEV ; Joe IWANAGA ; Aaron S. DUMONT ; R. Shane TUBBS
Anatomy & Cell Biology 2022;55(2):247-250
Variations of the skull base can affect surgical approaches and must be considered when viewing and interpreting radiological imaging. Here, we report a unique collection of bony anatomical variations found on a single adult skull. Three bony excrescences from the occipital bone were identified in the paracondylar region. The smallest of these processes was 7 mm long and was just medial to the mastoid process of the temporal bone and posterior to the styloid process. One bony process was attached to the occipital condyle and was 12 mm in length. The longest of these processes was 17 mm long and arose from the jugular process of the occipital bone. Paracondylar processes can be symptomatic. Knowledge of the bony variations at the skull base is important to those who operate in this region or review and interpret radiological imaging.
7.Morphology of the groove of the inferior petrosal sinus: application to better understanding variations and surgery of the skull base
Uduak-Obong I. EKANEM ; Łukasz OLEWNIK ; Andrea PORZIONATO ; Veronica MACCHI ; Joe IWANAGA ; Marios LOUKAS ; Aaron S. DUMONT ; Raffaele De CARO ; R. Shane TUBBS
Anatomy & Cell Biology 2022;55(2):135-141
Although adequate venous drainage from the cranium is imperative for maintaining normal intracranial pressure, the bony anatomy surrounding the inferior petrosal sinus and the potential for a compressive canal or tunnel has, to our knowledge, not been previously investigated. One hundred adult human skulls (200 sides) were observed and documented for the presence or absence of an inferior petrosal groove or canal. Measurements were made and a classification developed to help better understand their anatomy and discuss it in future reports. We identified an inferior petrosal sinus groove (IPSG) in the majority of specimens. The IPSG began anteriorly where the apex of the petrous part of the temporal bone articulated with the sphenoid part of the clivus, traveled posteriorly, in a slight medial to lateral course, primarily just medial to the petro-occipital fissure, and ended at the anteromedial aspect of the jugular foramen. When the IPSGs were grouped into five types. In type I specimens, no IPSG was identified (10.0%), in type II specimens, a partial IPSG was identified (6.5%), in type III specimens, a complete IPSG (80.0%) was identified, in type IV specimens, a partial IPS tunnel was identified (2.5%), and in type V specimens, a complete tunnel (1.0%) was identified. An improved knowledge of the bony pathways that the intracranial dural venous sinuses take as they exit the cranium is clinically useful. Radiological interpretation of such bony landmarks might improve patient diagnoses and surgically, such anatomy could decrease patient morbidity during approaches to the posterior cranial fossa.
8.Discovery of a trans-sellar vascular supply for the pituitary gland
Casey P. SPINELLI ; Joe IWANAGA ; Mi-Sun HUR ; Aaron S. DUMONT ; R. Shane TUBBS
Anatomy & Cell Biology 2022;55(2):124-129
The vasculature of the pituitary gland is discussed briefly and the details of an anatomical discovery of the vessels supplying the pituitary gland provided. Twenty latex injected cadaveric heads were dissected. Any vessels that were found to penetrate the sella turcica and travel to the pituitary gland were documented and measured. Additionally, 25 adult skulls were evaluated for the presence, size, and sites of bony foramina in the floor of sella turcica. Trans-sellar vessels were identified in 65% of specimens. There was a mean of 1.5 vessels per specimen consisting usually of a mixture of veins and arteries. The mean diameter of these vessels was 0.3 mm and the mean length from the sella turcica to the pituitary gland was 2.3 mm. These vessels were concentrated in the most concave part of the sella turcica. In bony specimens, the mean number of transsellar foramina was four. The diameter of these foramina ranged from 0.3 to 0.6 mm in size. The trans-sellar foramina were concentrated near the center part of the sella turcica and had no regular pattern. The pituitary gland receives at least some blood supply and drainage via vessels traveling along the septum of the sphenoidal sinuses and through the sella turcica.Knowledge of such vessels might lead to a better understanding of the vascular supply and drainage of the pituitary gland and would be useful during skull base approaches such as trans-nasal approaches to the pituitary gland.
9.The function of the tensor tympani muscle: a comprehensive review of the literature
Alexis EDMONSON ; Joe IWANAGA ; Łukasz OLEWNIK ; Aaron S. DUMONT ; R. Shane TUBBS
Anatomy & Cell Biology 2022;55(2):113-117
The tensor tympani muscle is structurally important in the middle ear, specifically through its involvement in the impedance of sound in response to intense auditory and non-auditory stimuli. Despite numerous studies, its true function has been debated for many years; questions still remain about its role in auditory and non-auditory reflexes and in sound damping. Some studies suggest that the tensor tympani muscle contracts as a result of non-auditory stimulation such as facial or head movements; others suggest that it contracts due to input from the cochlear nucleus, therefore by way of auditory stimulation. Whatever the cause, contraction of the tensor tympani muscle results in low frequency mixed hearing loss, either to protect the inner ear from loud sounds or to desensitize the ear to self-generated sounds. A review of these studies indicated that the tensor tympani muscle has a wide range of functions, yet the mechanisms of some of them have not been clearly demonstrated. One major question is whether the tensor tympani muscle contributes to sound damping; and if it does, what specific role it serves. The primary purpose of this review article is to explore the functions of the tensor tympani muscle in light of recent research advances.
10.Cadaveric findings of a duplicated superior petrosal sinus
Tina K. REDDY ; Łukasz OLEWNIK ; Joe IWANAGA ; Aaron S. DUMONT ; R. Shane TUBBS
Anatomy & Cell Biology 2022;55(3):384-389
Knowledge of the intracranial dural venous sinuses and their variations is important in the diagnosis and management of many cranial pathologies. We report a unique duplication of the right-sided superior petrosal sinus identified during routine dissection of the skull base.. Lateral to this sinus, a separate and more curvilinear superior petrosal sinus left the normally positioned superior petrosal sinus and traveled posteriorly near the foramen spinosum and then turned medially to drain into the normally positioned superior petrosal sinus. Anteriorly, the two sinuses joined together and drained into the cavernous sinus. Posteriorly, the laterally positioned sinus drained into the normally positioned sinus which then traveled in normal fashion along the petrous ridge to end in the transverse sinus. To our knowledge, such a duplication has not been previously reported in the extant medical literature.

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