1.Assessing household out-of-pocket expenditures for non-communicable diseases in a 4th class municipality: A cross-sectional study
Marivie R. Maganda ; Gwyneth Allyson B. Ibarra ; Charlene C. Laggui ; Frances Lois U. Ngo
Acta Medica Philippina 2025;59(Early Access 2025):1-19
BACKGROUND AND OBJECTIVE
Non-communicable diseases (NCDs) are medical conditions that are associated with long durations, slow progress, and lifetime medications. This study aimed to assess the household out-of-pocket (OOP) expenditures on NCDs in a 4th class municipality.
METHODSThis cross-sectional study was conducted to determine the characteristics of the households and household heads, healthcare needs, expenditures on medicines, health, and household, and alternative coping strategies to avail healthcare needs.
RESULTSThis study surveyed 200 households from all ten barangays of Ternate, Cavite. Top NCDs recorded include hypertension, diabetes, heart diseases, and asthma, while top NCDs medicines recorded were Losartan, Amlodipine, Metformin, and Glimepiride. Blood tests were the most needed medical laboratory service, while X-ray was the most needed diagnostic imaging service. Although more than half of the households have a member with only one NCD— the most prevalent being hypertensive disease, diabetes mellitus and other metabolic diseases—it is also common to have household members taking medicines for two to three NCDs.
CONCLUSIONThis study highlights the need to address issues with lack of access and availability of essential medicines for NCDs especially in the primary health care setting. This study provides evidence on the minimal financial risk protection provided for medicines with data suggesting that it is the primary cause of CHEs for NCDs. Households covered by the Primary Care Benefit Packages were excluded from the study, thus, the estimates derived from the sample may be an overestimate of the true prevalence of CHE in the municipality. Therefore, there is a need to have mechanisms in place to expand insurance coverage and increase government programs catering to certain population groups to reduce the financial burden of medicines for NCDs.
Human ; Noncommunicable Diseases ; Out-of-pocket Expenditures ; Health Expenditures ; Households ; Family Characteristics
2.Functions and experiences of male midwives in the Province of Aurora: An ethnographic qualitative study
Daisy Fangkingan - kaba-an ; Joel A. Valencia ; Jasmin M. Dumangeng ; Eva F. Dimog
Acta Medica Philippina 2025;59(Early Access 2025):1-10
BACKGROUND
This study explores the professional functions and experiences of male midwives in the Province of Aurora, highlighting their roles, challenges, and contributions to maternal and child healthcare in a traditionally female-dominated profession.
OBJECTIVEThis study aims to investigate the professional functions and lived experiences of male midwives in the Province of Aurora.
METHODSThis research employed a qualitative ethnographic design using semi-structured interviews to collect data. Participants were six male midwives practicing in Aurora. Data collection was conducted via mobile phone interviews from August to September 2024. A purposive sampling technique was utilized to select participants. The study adhered to ethical guidelines, receiving approval from the University of Northern Philippines Ethics Review Committee Code: 2024-251, and informed consent was obtained from all participants. Data were analyzed using qualitative content analysis. Qualitative inductive content analysis as described by Padgett was utilized to allow for data-driven analysis without pre-defined themes, making it suitable for exploring the diverse experiences of male midwives.
RESULTSAnalysis revealed six key themes: Diverse professional functions, gender bias and stereotyping, patient reluctance and shyness, cultural influences, experiences of discrimination and prejudice, and daily challenges and rewards in practice. The findings underscore the commitment of male midwives to providing quality care despite societal and professional barriers. Under the Functions theme, male midwives described their roles as not only caregivers but also as advocates for gender inclusivity in midwifery. In terms of experiences, some reported feelings of isolation and the need to prove their competence in a field dominated by women. However, they also shared empowering stories of camaraderie with female colleagues and the satisfaction derived from breaking down gender barriers.
CONCLUSIONMale midwives play a vital role in maternal and newborn healthcare, navigating challenges such as gender bias and patient hesitancy. Strengthening administrative support, promoting inclusivity, and updating policies can enhance their professional integration. Advocacy efforts from professional organizations are necessary to address workplace challenges and recognize their contributions to healthcare.
Human ; Male ; Midwifery ; Gender Bias ; Sexism ; Maternal Health ; Community ; Residence Characteristics
3.Perspectives of the Filipino LGBTQ+ community in the National Capital Region in healthcare: A photovoice project
Rod Charlie Delos Reyes ; Jamie Ann Arnes ; Leilani Apostol-Nicodemus ; Erica Gabrielle Delos Reyes
Philippine Journal of Health Research and Development 2025;29(1):3-9
BACKGROUND
LGBTQ+ populations worldwide bear a disproportionate burden of health disparities aggravated by stigma and discrimination in healthcare. This struggle is worsened in the Philippines due to systemic barriers, outdated medical curricula, and the pervasive stigma in society, making it harder for LGBTQ+ individuals to access healthcare.
METHODOLOGYA community-based participatory research (CBPR) approach using the photovoice method was used to describe and co-construct perspectives from LGBTQ+ individuals related to healthcare access in the Philippine healthcare system. The LGBTQ+ participants who resided in Metro Manila were asked to capture photographs representing their healthcare experiences. Focused group discussions (FGD) were then utilized as a platform for collective discussions and interpretations of these photos, enabling the participants to voice their stories and views about healthcare access.
RESULTSThe results are represented in seven photographs, symbolizing seven key themes that are illustrative of the importance of narrating LGBTQ+ stories in healthcare, solidarity among the community for better access, the urgent need for a call to make healthcare spaces inclusive, navigation through intersecting identities, interaction between healthcare professionals and LGBTQ+ individuals, the call for systemic change to be fitted to the needs of LGBTQ+ people, and diverse healthcare challenges among transgender people.
CONCLUSIONThe findings point to the strong call for systemic reforms in the Philippine healthcare system to better support the needs of LGBTQ+ people. This study highly recommends that lived experiences should be included in health practices and policies as a basis for inclusivity and equity.
Human ; Residence Characteristics
5.Gender influence on hyperacute intracerebral hemorrhage prognosis: A demographic, clinical and radiologic analysis
John Christopher V. Ruiz ; Sherielyn Bayani ; Marian Irene Escasura
Philippine Journal of Neurology 2025;28(1):52-57
BACKGROUND
There is growing interest in gender differences in acute stroke worldwide. However, no known studies have been published on the differences in prognosis of hyperacute intracerebral hemorrhage between genders among Asians, particularly Filipinos.
OBJECTIVESCompare gender differences in the prognosis of hyperacute intracerebral hemorrhage in terms of baseline demographic and radiologic profile, as well as, clinical outcomes.
METHODSThis is a retrospective cohort study involving a chart review of all patients diagnosed with hyperacute Intracerebral Hemorrhage admitted at a tertiary hospital from January 2021 to May 2023. Patients were grouped according to their gender and baseline demographic, radiologic and clinical outcomes were assessed and compared between two groups.
RESULTSNo statistical difference was found between stroke risk factors between the two groups. However, males tend to have higher percentages of intraventricular extension (29.2 %. (n=28) vs 30.6% (n=11) and increased hematoma volume compared to their female counterparts (n=39, 83% vs n=11, 68%). In addition, males had a higher number of ICU admissions (42.7% (n= 41) vs. 33.3% (n= 12) and mortality (46.9%( n=45) vs. 30.6% (n=11), though the results were not statistically significant.
CONCLUSIONIn patients with hyperacute intracerebral hemorrhage, gender does not influence on its radiologic and clinical outcome.
Human ; Stroke ; Gender Identity ; Gender Differences ; Sex Characteristics
6.Lived experiences of frail older persons living alone in Quezon City
Lynard Andrew P. Cueto ; Ma. Teresa Tricia G. Bautista ; Goldie Lynn D. Diaz
The Filipino Family Physician 2025;63(1):39-44
BACKGROUND
Growing old is a remarkable journey filled with diverse experiences and wisdom. It’s a time when individuals often reflect on their lives, cherish memories, and share invaluable lessons with younger generations. Understanding aging is crucial as it encompasses more than just physiological and psychological processes, to comprehend the subjective sensations of the phenomenon of “being an elderly person”.
OBJECTIVEThe purpose of this study was to describe the daily lives of frail older adults living alone in Quezon City.
METHODSThe study utilized a qualitative research design. The approach employed was a descriptive phenomenological study describing the fundamental nature of being an elderly. The population consisted of frail older adult people (>60 years old) assessed using the Clinical Frailty Scale and living alone in Quezon city using a purposive sampling of those who were present in their homes during the designated interview period. The study was conducted in a private, safe and secured place both agreed by the participants and the researcher through face to face interview.
RESULTSBeing an frail older adult in this study essentially involves balancing one’s life in a flow of motion. The older adult is balancing a number of life-altering events and a shift in their circumstances influenced by recollections from various stages of life. In the life of an older adult, all ages are harmonious and wisely expressed and developed from pleasant and lovely or less pleasant and beautiful or more stressful early life experiences that went throughout adolescence and young adulthood, middle age, and later years. Their family, children and grandchildren were their source of strength and inspiration.
CONCLUSIONThis study gave light on the realities faced daily by a frail older adult. Insights gained from this study serve as an opportunity to develop or innovate appropriate support. This information is crucial for clinicians, community-based aged care providers, legislators, elderly associations, and other concerned citizens. On a local level, the government unit’s key officials or proponents for the welfare of older adults are encouraged to delve deeper and focus on the unique needs and life experiences of the elderly population.
Human ; Family Characteristics
7.Functions and experiences of male midwives in the Province of Aurora: An ethnographic qualitative study.
Daisy FANGKINGAN - FABA-AN ; Joel A. VALENCIA ; Jasmin M. DUMANGENG ; Eva F. DIMOG
Acta Medica Philippina 2025;59(18):61-70
BACKGROUND
This study explores the professional functions and experiences of male midwives in the Province of Aurora, highlighting their roles, challenges, and contributions to maternal and child healthcare in a traditionally female-dominated profession.
OBJECTIVEThis study aims to investigate the professional functions and lived experiences of male midwives in the Province of Aurora.
METHODSThis research employed a qualitative ethnographic design using semi-structured interviews to collect data. Participants were six male midwives practicing in Aurora. Data collection was conducted via mobile phone interviews from August to September 2024. A purposive sampling technique was utilized to select participants. The study adhered to ethical guidelines, receiving approval from the University of Northern Philippines Ethics Review Committee Code: 2024-251, and informed consent was obtained from all participants. Data were analyzed using qualitative content analysis. Qualitative inductive content analysis as described by Padgett was utilized to allow for data-driven analysis without pre-defined themes, making it suitable for exploring the diverse experiences of male midwives.
RESULTSAnalysis revealed six key themes: Diverse professional functions, gender bias and stereotyping, patient reluctance and shyness, cultural influences, experiences of discrimination and prejudice, and daily challenges and rewards in practice. The findings underscore the commitment of male midwives to providing quality care despite societal and professional barriers. Under the Functions theme, male midwives described their roles as not only caregivers but also as advocates for gender inclusivity in midwifery. In terms of experiences, some reported feelings of isolation and the need to prove their competence in a field dominated by women. However, they also shared empowering stories of camaraderie with female colleagues and the satisfaction derived from breaking down gender barriers.
CONCLUSIONMale midwives play a vital role in maternal and newborn healthcare, navigating challenges such as gender bias and patient hesitancy. Strengthening administrative support, promoting inclusivity, and updating policies can enhance their professional integration. Advocacy efforts from professional organizations are necessary to address workplace challenges and recognize their contributions to healthcare.
Human ; Male ; Midwifery ; Gender Bias ; Sexism ; Maternal Health ; Community ; Residence Characteristics
8.Assessing household out-of-pocket expenditures for non-communicable diseases in a 4th class municipality: A cross-sectional study.
Marivie R. MAGANA ; Gwyneth Allyson B. IBARRA ; Charlene C. LAGGUI ; Frances Lois U. NGO
Acta Medica Philippina 2025;59(15):47-65
BACKGROUND AND OBJECTIVE
Non-communicable diseases (NCDs) are medical conditions that are associated with long durations, slow progress, and lifetime medications. This study aimed to assess the household out-of-pocket (OOP) expenditures on NCDs in a 4th class municipality.
METHODSThis cross-sectional study was conducted to determine the characteristics of the households and household heads, healthcare needs, expenditures on medicines, health, and household, and alternative coping strategies to avail healthcare needs.
RESULTSThis study surveyed 200 households from all ten barangays of Ternate, Cavite. Top NCDs recorded include hypertension, diabetes, heart diseases, and asthma, while top NCDs medicines recorded were Losartan, Amlodipine, Metformin, and Glimepiride. Blood tests were the most needed medical laboratory service, while X-ray was the most needed diagnostic imaging service. Although more than half of the households have a member with only one NCD— the most prevalent being hypertensive disease, diabetes mellitus and other metabolic diseases—it is also common to have household members taking medicines for two to three NCDs.
CONCLUSIONThis study highlights the need to address issues with lack of access and availability of essential medicines for NCDs especially in the primary health care setting. This study provides evidence on the minimal financial risk protection provided for medicines with data suggesting that it is the primary cause of CHEs for NCDs. Households covered by the Primary Care Benefit Packages were excluded from the study, thus, the estimates derived from the sample may be an overestimate of the true prevalence of CHE in the municipality. Therefore, there is a need to have mechanisms in place to expand insurance coverage and increase government programs catering to certain population groups to reduce the financial burden of medicines for NCDs.
Human ; Noncommunicable Diseases ; Out-of-pocket Expenditures ; Health Expenditures ; Households ; Family Characteristics
9.A phenome-wide spectrum of morbidity and mortality risks related to the number of offspring among 0.5 million Chinese men and women: A prospective cohort study.
Meng XIAO ; Aolin LI ; Canqing YU ; Yuanjie PANG ; Pei PEI ; Ling YANG ; Yiping CHEN ; Huaidong DU ; Yujie HUA ; Junshi CHEN ; Zhengming CHEN ; Jun LYU ; Liming LI ; Dianjianyi SUN
Chinese Medical Journal 2025;138(22):2925-2937
BACKGROUND:
Prospective evidence on how offspring number influences morbidity and mortality remains limited. This study investigated the associations between number of offspring and morbidity and mortality risks among 0.5 million Chinese adults.
METHODS:
By using data from the China Kadoorie Biobank (CKB; n = 512,723, an approximately 12-year follow-up), sex-stratified phenome-wide association study (PheWAS) analyses were conducted to investigate associations between offspring number (without vs . with offspring; more than one vs . one offspring) and risks of ICD10-coded morbidity and mortality. Sex-specific adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs) were estimated by Cox proportional-hazards models.
RESULTS:
Among 210,129 men and 302,284 women aged 30-79 years, 1,338,837 incident events were recorded. PheWAS results revealed that offspring number was associated with disease risks across multiple systems. Cox models showed that childless men ( vs . one offspring) had higher risks for nine of 36 diseases, while childless women for five of 37. Each additional offspring was associated with reduced risks of mental and behavioral disorders in men (aHR [95% CI] = 0.93 [0.87-0.98]) and both mental and behavioral disorders (aHR [95% CI] = 0.93 [0.89-0.97]) and breast cancer (aHR [95% CI] = 0.82 [0.78-0.86]) in women. However, each additional offspring was associated with a 4% increase in the risk of cholelithiasis and cholecystitis in women (aHR [95% CI] = 1.04 [1.02-1.07]). Among 282,630 patients, 44,533 deaths were documented. Childless patients had higher mortality risk in both men (aHR [95% CI] = 1.37 [1.28-1.47]) and women (aHR [95% CI] = 1.27 [1.15-1.41]). For men, each additional offspring reduced mortality by 4% (aHR [95% CI] = 0.96 [0.95-0.98]), while for women, the lowest risk was observed among those with three to four offspring ( Pnonlinear <0.0001).
CONCLUSIONS
Offspring number is closely linked to morbidity and mortality risks. Further research is warranted to verify our findings and clarify the underlying mechanisms involved.
Adult
;
Aged
;
Female
;
Humans
;
Male
;
Middle Aged
;
China/epidemiology*
;
Morbidity
;
Proportional Hazards Models
;
Prospective Studies
;
Risk Factors
;
Family Characteristics
;
Mortality
;
East Asian People
10.Transcriptomic analysis of key genes involved in sex differences in intellectual development.
Jia-Wei ZHANG ; Xiao-Li ZHENG ; Hai-Qian ZHOU ; Zhen ZHU ; Wei HAN ; Dong-Min YIN
Acta Physiologica Sinica 2025;77(2):211-221
Intelligence encompasses various abilities, including logical reasoning, comprehension, self-awareness, learning, planning, creativity, and problem-solving. Extensive research and practical experience suggest that there are sex differences in intellectual development, with females typically maturing earlier than males. However, the key genes and molecular network mechanisms underlying these sex differences in intellectual development remain unclear. To date, Genome-Wide Association Studies (GWAS) have identified 507 genes that are significantly associated with intelligence. This study first analyzed RNA sequencing data from different stages of brain development (from BrainSpan), revealing that during the late embryonic stage, the average expression levels of intelligence-related genes are higher in males than in females, while the opposite is observed during puberty. This study further constructed interaction networks of intelligence-related genes with sex-differential expression in the brain, including the prenatal male network (HELP-M: intelligence genes with higher expression levels in prenatal males) and the pubertal female network (HELP-F: intelligence genes with higher expression levels in pubertal females). The findings indicate that the key genes in both networks are Ep300 and Ctnnb1. Specifically, Ep300 regulates the transcription of 53 genes in both HELP-M and HELP-F, while Ctnnb1 regulates the transcription of 45 genes. Ctnnb1 plays a more prominent role in HELP-M, while Ep300 is more crucial in HELP-F. Finally, this study conducted sequencing validation on rats at different developmental stages, and the results indicated that in the prefrontal cortex of female rats during adolescence, the expression levels of the intelligence genes in HELP-F, as well as key genes Ep300 and Ctnnb1, were higher than those in male rats. These genes were also involved in neurodevelopment-related biological processes. The findings reveal a sex-differentiated intelligence gene network and its key genes, which exhibit varying expression levels during the neurodevelopmental process.
Female
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Intelligence/physiology*
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Male
;
Sex Characteristics
;
Animals
;
Brain/growth & development*
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E1A-Associated p300 Protein/physiology*
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beta Catenin/physiology*
;
Transcriptome
;
Rats
;
Gene Expression Profiling
;
Genome-Wide Association Study


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