Objective To observe the value of 2D SECara-Net and 3D U2-Net models constructed based on 2D maximal intensity projection(MIP)and 3D time-of-flight MR angiography(3D TOF-MRA)images,respectively,also of their combination for MRA detecting unruptured saccular intracranial aneurysms(USIA).Methods Totally 973 patients with single USIA and 300 subjects who underwent healthy physical examination were retrospectively collected and divided into training set(n=923,containing 723 cases of USIA and 200 healthy subjects)and test set(n=350,containing 250 cases of USIA and 100 healthy subjects)at the ratio of 7:3.Pre-processed 3D TOF-MRA and the obtained 2D-MIP images in training set were imported into 3D U2-Net and 2D SECara-Net models for training and adjusting parameters,respectively.The efficiency of 2 models and their combination for detecting USIA were evaluated.Results The sensitivity,specificity and accuracy of 2D SECara-Net model for detecting USIA in test set was 78.80％(197/250),95.00％(95/100)and 83.43％(292/350),of 3D U2-Net model was 82.80％(207/250),86.00％(86/100)and 83.71％(293/350),respectively.The specificity of 2D SECara-Net model was higher than that of 3D U2-Net model(P=0.030),while no significant difference of sensitivity nor accuracy was found between 2 models(both P＞0.05).The specificity of the combination of the 2 models was 99.00％(99/100),higher than that of 3D U2-Net model(P＜0.05),and the sensitivity and accuracy of the combination was 91.20％(228/250)and 93.43％(327/350),respectivelty,both higher than those of 2 single models(all P＜0.05).Conclusion 2D SECara-Net and 3D U2-Net models had similar,sensitivity and accuracy for MRA detecting USIA.Combination of them could improve the detecting efficacy.

Objective To observe the value of 2D SECara-Net and 3D U2-Net models constructed based on 2D maximal intensity projection(MIP)and 3D time-of-flight MR angiography(3D TOF-MRA)images,respectively,also of their combination for MRA detecting unruptured saccular intracranial aneurysms(USIA).Methods Totally 973 patients with single USIA and 300 subjects who underwent healthy physical examination were retrospectively collected and divided into training set(n=923,containing 723 cases of USIA and 200 healthy subjects)and test set(n=350,containing 250 cases of USIA and 100 healthy subjects)at the ratio of 7:3.Pre-processed 3D TOF-MRA and the obtained 2D-MIP images in training set were imported into 3D U2-Net and 2D SECara-Net models for training and adjusting parameters,respectively.The efficiency of 2 models and their combination for detecting USIA were evaluated.Results The sensitivity,specificity and accuracy of 2D SECara-Net model for detecting USIA in test set was 78.80％(197/250),95.00％(95/100)and 83.43％(292/350),of 3D U2-Net model was 82.80％(207/250),86.00％(86/100)and 83.71％(293/350),respectively.The specificity of 2D SECara-Net model was higher than that of 3D U2-Net model(P=0.030),while no significant difference of sensitivity nor accuracy was found between 2 models(both P＞0.05).The specificity of the combination of the 2 models was 99.00％(99/100),higher than that of 3D U2-Net model(P＜0.05),and the sensitivity and accuracy of the combination was 91.20％(228/250)and 93.43％(327/350),respectivelty,both higher than those of 2 single models(all P＜0.05).Conclusion 2D SECara-Net and 3D U2-Net models had similar,sensitivity and accuracy for MRA detecting USIA.Combination of them could improve the detecting efficacy.

Objective To approach the clinical value of ultrasound-guided percutaneous transhepatic cholangiographic drainage (PTCD) in the treatment of malignant obstructive jaundice.Methods Twenty-five patients with malignant obstructive jaundice were treated with uhrasound-guided PTCD,and the therapeutic effect and complications were observed.Results All the patients were successfully punctured,and the successful rate of single puncture was 92.00% (23/25) .Jaundice of all the patients decreased 3 to 6 days after PTCD.The serum total bilirubin and the inner diameter of intrahepatic ducts decreased after PTCD.The complications included bile exudation and slight bloody bile (either 1 patient) .Conclusion Ultrasound-guided PTCD is a simple,safe and effective way to reduce jaundice,and can be regarded as the first choice in the treatment of malignant obstructive iaundice.

The breakdown voltage plays an important role in evaluating residual life of stator insulation in generator. In this paper, we discussed BP neural network that was used to predict the breakdown voltage of stator insulation in generator of 300 MW/18 kV. At first the neural network has been trained by the samples that include the varieties of dielectric loss factor tanδ, the partial discharge parameters and breakdown voltage. Then we tried to predict the breakdown voltage of samples and stator insulations subjected to multi-stress aging by the trained neural network. We found that it's feasible and accurate to predict the voltage. This method can be applied to predict breakdown voltage of other generators which have the same insulation structure and material.

Objective To determine the treatment outcome and prognosis after resection of esophageal cancer.Methods 312 patients who developed recurrence after curative resection for squamous cell cancer of the thoracic esophagus were analyzed retrospectively.Results Recurrence was found after a mean period of 17.8 months(range 2～56 months).Recurrence pattern was catagorized into lymphatic,hematogerous,mixed and anastomotic.The number of patients in each recurrence group was 188,42,60,22.312 patients were enveloped into a noadjuant treatment group(NT,68),a radiotherapy alone group(RT,110),a chemotherapt group(CT,72) and a radiotherapy combined chemothepapy(CRT+CT,32).The 0.5-,1-,2-and 3-year overall survival rates for NT were 63.5%,35.2%,16.3% and 13.1%;For CT were 65.7%,52.3%,11.9% and 9.2%;For RT were 75.6%,49.2%,32.2% and 14.2%,respectively.Compared with CT there were significant differences in survival for patients receiving RT alone or combined with CT(P0.05).Multivariate analysis showed that depth of tumor invasion,lymph node metastasis,operative procedure and different regimens of therapy were significant prognostic factors.Conclusion Esophagectomy with cervical anastomasis is recommened for esophageal carcinoma,additional cervical lymphadenectomy is benefical in a few patients.Radiotherapy or combined with chemotherapy to be effective in prolonging the survival of patietns with recurrenes after esophageal resection for cancer.Investigation for more effective drugs and regimens of chemotherapy need to be taken.

Objective To evaluate the function of residual esophagus and stomach after subtotal esophagectomy and cervical gastroesophagostomy for esophageal carcinoma. Methods Manometry was performed in 21 patients who underwent cervical anastomosis after subtotal esophageal resection. The data was compared with normal subjects. Results The mean value of pharyngeal resting pressure was (1.20?2.03) mmHg(1mmHg=0.133kPa), and that of contraction pressure was (72.37?16.95) mmHg. The resting pressure of upper esophageal sphincter (UES) was (28.20?15.60) mmHg, and closing pressure was (107.10?28.43) mmHg. The resting pressure of residual esophagus was (15.98?11.10) mmHg, and contraction pressure was (48.45?18.37) mmHg. The resting pressure of stomach was (3.53?3.30) mmHg. Incidence of primary wave of esophagus was (57.14?34.50)%. The resting pressure of residual esophagus was much higher than that of normal group (P

This paper presents the experience of surgical treatment of 32 patients with esophageal stricture caused by corrosive burn. The modes of surgical treatment in this series included: instrumental dilatation in 11 cases, reconstruction with resection of strictured esophagus in 19 (pharyngogas-trostomy in 6, cervical esophagogastrostomy in 12 and colon interposition in 1) and reoperation for esophageal restenosis in 2, There was no operative morality. All patients were fol- lowed-up and 94% of them resumed their normal diet post-operatively. The author recommend that dilatation can be applied to patients with localized esophageal stricture or slight annular stricture, and should done early. Resection of the esophageal stricture and esophagal reconstruction can be used in patients with extensive or severe stricture. There are many ways to esophageal reconstruction. The optimal one should meet the following requirements: isoperistaltic segment without tension and rich in blood supply, it should be easy to perform and result in no restenosis.

The resected specimens of esophageal adenocarcinoma from 73 patients were studied pathohistologically. The results demonstrated stage I in 1 cases; stage IIA 37; stage HB 8 and stage III 27. The incidence of postoperative complications and operative mortality were 4.1% and 1.4% respectively. The overall 5 year survival rate was 28. 3%. The authors pointed out that patients with primary esophageal adenocarcinoma should be operated on early. Even the late stage patients should also be treated surgically, because the esophageal adenocarcinoma is neither sensative to chemotherapy, nor radiotherapy.