1.Efficacy of unilateral biportal endoscopic surgery versus percutaneous transforaminal endoscopic discectomy in treating lumbar spinal stenosis
Zemin WANG ; Jiongwen LU ; Zhongbin CAI ; Yujuan XIE ; Xianglin XU ; Haixin LIU ; Jianqi LU
Journal of Navy Medicine 2024;45(7):710-714
Objective To compare the efficacies of unilateral biportal endoscopic(UBE)technique and percutaneous transforaminal endoscopic discectomy(PTED)in the treatment of lumbar spinal stenosis.Methods Forty patients who were diagnosed with lumbar spinal stenosis in Chashan Hospital of Dongguan from January 2019 to January 2023 were enrolled in this retrospective study.They were divided into PTED group(n=20)and UBE group(n=20).Perioperative data(operation time,intraoperative bleeding,postoperative hospital stay,degree of decompression and complications)were compared between the two groups.Visual analogue scale(VAS)score and Oswestry dysfunction index(ODI)were collected before surgery and on 3 days,1 month and 6 months after surgery.Results There were no significant differences in the operation time,intraoperative bleeding,or hospitalization time between the two groups(all P>0.05).The incidence of postoperative complications in the UBE group was significantly lower than that in the PTED group(P=0.001).VAS score and ODI of the low back and leg pains in the UBE group were superior to the PTED group at each postoperative time point(all P<0.05).One month after surgery,the UBE group had a more significant increase in the dural sac cross-sectional area and intervertebral foramen area than the PTED group(t=3.842,P=0.003;t=2.469,P=0.006).Conclusion Compared with PTED,UBE has better clinical outcomes,higher degree of decompression,and lower incidence of complications.UBE is a safe and feasible surgical method for the treatment of lumbar spinal stenosis.
2.Research progress on the relationship between pentraxin 3 and Henoch-Schonlein purpura
Lu LIU ; Yongqiang ZHOU ; Zhongbin TAO ; Yuning LI
Chinese Journal of Applied Clinical Pediatrics 2021;36(9):714-717
Henoch-Schonlein purpura (HSP) is one of the most common clinical manifestations of systemic small vasculitis in children with non-thrombocytopenic, and mainly manifested as skin purpura, arthritis, gastrointestinal symptoms and Henoch-Schonlein purpura nephritis (HSPN). The severity of renal involvement is the main factor determining the long-term prognosis of children with HSP.Studies have revealed that the determination of pentraxin 3 (PTX3) in serum can be used for early diagnosis of HSPN and prediction of renal injury.In this paper, the origin, gene and protein structure, function, potential relationship and mechanism of action between PTX3 and HSP were discussed, so as to provide new ideas for the early diagnosis and treatment of HSPN.
3.The application of multiple MR sequences in detection of children small bowel intestinal diseases
Lichun ZHU ; Kefei HU ; Jun HU ; Xu LI ; Zifeng SHI ; Zhongbin LU ; Xiaobo WANG
Journal of Practical Radiology 2016;32(5):764-767
Objective To investigate the application value of magnetic resonance enterography (MRE) with multiple sequences in detection of children bowel intestinal diseases .Methods Retrospective analysis of 35 patients with bowel diseases confirmed by clini‐cal results ,surgery and pathology was performed .The patients underwent MRE with multiple sequences including T 1WI ,fat‐suppressed T2 WI ,diffusion weighted imaging (DWI) ,single‐shot fast spin‐echo (SSh‐TSE) sequence ,rapid balance fast field echo (B‐FFE) ,and unenhanced and enhanced fat‐suppressed (FFE‐IP‐SPAIR) scans .Results SSh‐TSE showed the whole intestinal distribution in 34 patients (34/35);DWI showed the lesions with high signal in 29 (29/35);T1WI and fat‐suppressed T2 WI showed hyperintensity on T2WI in 3 ,slight hypointensity on T1WI and T2WI in 2 ,and hyperintensity on T1WI and hypointensity on T2WI in 1 .Enhancement of lesion was found in 28 ,and unenhancement was in 2 .Conclusion MRE with multiple sequences with more information ,sensitivity and non‐ionizing radiation ,can be used as an important method in diagnosis of children intestinal diseases .
4.Value of MRI in the diagnosis of fetal aortic arch anomalies
Xu LI ; Kefei HU ; Chuangao YIN ; Gengwu LI ; Zhongping MU ; Xuelei LI ; Jun HU ; Xiaobo WANG ; Zhongbin LU
Chinese Journal of Radiology 2015;(9):694-697
Objective To explore the value of MRI in the diagnosis of fetal aortic arch anomalies. Methods We retrospectively collected 10 fetuses with aortic arch anomalies indicated by prenatal ultrasound and underwent MR examination and were subsequently proven by autopsy or post-birth follow-up from 320 pregnant women. We focused on the observations of the location of the aortic arch and brachiocephalic artery anomalies, the locations of the liver and stomach in the abdominal cavity, and the large vessels in abdomen. The above-mentioned finding were compared with prenatal ultrasound and follow-up findings. Results Of 10 cases, right aortic arch with aberrant left subclavian artery was seen in 7 cases, right aortic arch with the mirror branch, left aortic arch with aberrant right subclavian artery, right aortic arch with aberrant left subclavian artery combined with cervical aortic arch and double aortic arch was seen in 1 case, respectively. All aortic arch anomalies detected by MRI were consistent with post-birth or autopsy findings. Ultrasound misdiagnosed aortic branch malformation in 5 places, which included right aortic arch but misdiagnosed aberrant left subclavian artery in 2 cases, right aortic arch never diagnosed mirror branch anomaly in 1 case, right aortic arch with left subclavian artery misdiagnosed cervical aortic arch in 1 case, left atrial isomerism but misdiagnosed left aortic arch with aberrant right subclavian artery in 1 case;One double aortic arch was misdiagnosed as right aortic arch with aberrant left subclavian artery in ultrasound. Conclusion Fetal cardiovascular MRI is an effective and supplementary examination to complement ultrasound in diagnosis of fetal aortic arch anomalies.

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