1.VALIDATION AND RELIABILITY OF A GUIDED QUESTIONNAIRE (GQ) FOR TYPE 1 DIABETES MELLITUS (T1DM) CHILDREN AND PARENTS ON PERIODONTAL DISEASE (PD)
Zaridah Zainal Abidin ; Rohaida Abdul Halim ; Erni Noor ; Noor Shafina Mohd Nor ; Nor Shafina Mohamed Nazari ; Azriyanti Anuar Zaini ; Nurul Zeety Azizi ; Shahrul Aiman Soelar
Journal of University of Malaya Medical Centre 2024;27(2):13-24
VALIDATION AND RELIABILITY OF A GUIDED QUESTIONNAIRE (GQ) FOR TYPE 1 DIABETES MELLITUS (T1DM) CHILDREN AND PARENTS ON PERIODONTAL DISEASE (PD)
The prevalence of PD is notably high in individuals with T1DM. Despite this, there is a limited availability of research on the utilization of questionnaires to evaluate self-perceived PD, patient knowledge, and their perception of PD in T1DM patients. Therefore, our objective was to establish validity and reliability of a bilingual (English-Malay) version of the guided questionnaire (GQ) to be used among pediatric T1DM patients attending Universiti Teknologi MARA (UiTM) Sungai Buloh campus and the Universiti Malaya (UM). This questionnaire focused on self-reported periodontal disease (PD), assessing their knowledge, and understanding of the bidirectional relationship between
PD and T1DM. The dual-language GQ was adapted from the Self-Reported Questionnaire Malay Modified (SRQMM) to suit the targeted participants. Content validation was carried out among five field experts, and face validation was done among pediatric patients in Dental Faculty UiTM. Reliability testing was administered in T1DM patients attending UiTM and UM. The structure and words of the component in GQ were modified to ensure that it was appropriate for the participants. The item-level Content Validity Index (I-CVI) turned out to be valid with an average of 0.98. The subjective measurement of face validation showed satisfactory results after the second revision. Reliability concerning Cronbach’s alpha (α) values was computed relying on all 21 items, which were acceptable
at about 0.777, 0.644, 0.780 in the self-perceived PD assessment domain, knowledge domain and perception domain, respectively. Hence, the adapted dual language paediatrics version of the GQ is a reliable and valid tool for assessing self-perceived PD, knowledge, and perception in T1DM patients on PD and it can be effectively utilized by non-dental healthcare personnel.
2.Extra-anatomical veno-venous surgical bypass for central vein occlusion in patients with ipsilateral arterio-venous fistula (AVF) for haemodialysis - A single centre experience
Saravana Kumar Selvanathan ; Zainal Ariffin Azizi
The Medical Journal of Malaysia 2017;72(1):3-6
Objective: Central vein occlusion is a common complication
related to central vein catheter insertion for haemodialysis
which can be unmasked by an ipsilateral fistula creation,
leading to a dysfunctional arteriovenous fistula (AVF). We
describe an extra-anatomical venous bypass surgical
procedure performed to maintain vascular access and
reduce the symptoms of swelling of the ipsilateral upper
limb, neck and face.
Materials and Methods: We report 20 consecutive patients
with end-stage renal failure (ESRF) who had central vein
occlusion and were not amenable to endovascular
intervention. They underwent extra-anatomical vein to vein
surgical bypass. The axillary and iliac or femoral veins were
approached via infraclavicular and extraperitoneal groin
incisions respectively. In all the patients, an externally
supported 6 or 8 mm polytetrafluoroethylene (PTFE) graft
was used as a conduit and was tunnelled extra-anatomical.
All patients had double antiplatelet (Aspirin and Clopidogrel)
therapy post-operatively.
Results: Substantial improvement in the facial, neck and
upper limb swelling was noticed following this diversion
surgery. The vein to vein bypass was patent at 12 months in
10 out of 20 patients. Graft infection occurred in two (10%)
cases. Re-thrombectomy or assisted patency procedure
(stent/plasty) was done in four (20%) cases. The patients
with preoperative fistula flow rate of more than 1500 ml/min
and post-operative graft flow rate of more than a 1000 ml/min
were patent at 12 months (P=0.025 and p=0.034
respectively).
Conclusion. Axillary to iliac/femoral vein bypass can salvage
functioning ipsilateral fistula threatened by occluded upper
central vein and relieve their upper limb obstructive venous
symptoms.
3.Total percutaneous endovascular aneurysm repair (pEVAR): the initial experience in Hospital Kuala Lumpur
Benjamin DK Leong ; Naresh Govindarajanthran ; Hafizan Mohd Tajri ; Kia Lean Tan ; Hanif Hussein ; Zainal Ariffin Azizi
The Medical Journal of Malaysia 2017;72(2):91-93
Introduction: There has been a paradigm shift in the
treatment of AAA with the advent of endovascular aneurysm
repair (EVAR). Rapid progress and evolution of
endovascular technology has brought forth smaller profile
devices and closure devices. Total percutaneous
endovascular aneurysm repair (pEVAR) involves the usage
of suture-mediated closure devices (SMCDs) at vascular
access sites to avoid a traditional surgical cutdown.
Materials And Methods: We retrospectively reviewed our
experience of pEVAR between April 2013 and July 2014.
Primary success of the procedure was defined as closure of
a common femoral artery (CFA) arteriotomy without the need
for any secondary surgical or endovascular procedure
within 30 days.
Results: In total there were 10 pEVAR cases performed in the
study period, one case in Queen Elizabeth Hospital during
visiting vascular service. Patients have a mean age of 73.4
year old (66-77 year old) The mean abdominal aortic size was
7.2 cm (5.6-10.0cm). Mean femoral artery diameter was 9.0
mm on the right and 8.9 mm on the left. Mean duration of
surgery was 119 minutes (98- 153 minutes). 50% of patients
were discharged at post-operative day one, 30%- day two
and 20%- day three. Primary success was achieved in 9
patients (90%) or in 19 CFA closures (95%). No major
complication was reported.
Discussion: We believe that with proper selection of patients
undergoing EVAR, pEVAR offers a better option of vascular
access with shorter operative time, less post- operative
pain, shorter hospital stay and minimises the potential
complications of a conventional femoral cutdown.
4.Endovascular stent graft repair of aorto-iliac pseudoaneurysms - Hospital Kuala Lumpur experience
Nan Chuang Khang ; Zainal Ariffin bin Azizi
The Medical Journal of Malaysia 2016;71(1):17-22
Background: This is a single institutional review of aortoiliac
pseudoaneurysm of various aetiologies managed with
endovascular stent graft repair.
Methods: From 2009 to 2014, 16 patients had endovascular
stent graft inserted for pseudoaneurysm of the thoracic
aorta, abdominal aorta and iliac arteries in Hospital Kuala
Lumpur. Co-morbidity, causative agents, in-hospital
mortality, complications and outcomes were examined.
Results: The average age was 59.1 years (range 36-77).
Comorbidities include hypertension, diabetes mellitus,
tuberculosis, prior infection and previous open aneurysmal
repair. All patients had raised WBC (>10.0x109 /L), ESR or Creactive
protein on admission while 50% of patients had
fever. Blood cultures were positive in 4 patients. All patients
were given antibiotics. Only one in-hospital mortality was
noted at day-47 post-procedure. Two patients died of aortoenteric
fistula at district hospital eight and 16 months later.
One patient died of chronic graft infection two years later.
One died of unrelated cause. One patient developed type IB
endoleak from internal iliac artery two years later and
surgical ligation was performed. The average follow up was
15.8 months.
Conclusion: Endovascular stent graft repair for
pseudoaneurysm is a viable option compared to open
surgery. It is less invasive, has lower operative morbidity
and fair outcomes. However, some cases may be due to
inflammatory aortitis instead of infective pseudoaneurysm,
given the frequent culture-negative results. In order to
obtain high yield of bacteria culture for infected
pseudoaneurysm, open repair with tissue culture is still the
main mode of treatment especially for patients with low comorbidity.
Aneurysm, False
5.Thoracic Aortic Aneurysm as A Cause of Ortner’s Syndrome – A Case Series
Ismazizi Zaharudin ; Zainal Ariffin Azizi
The Medical Journal of Malaysia 2016;71(3):139-141
Hoarseness due to left recurrent laryngeal nerve paralysis
was first described in 1897 by Norbert Ortner. Various
cardiopulmonary and thoracic arch aorta pathologies
associated with left recurrent laryngeal nerve palsy have
been described over the last 100 years and is also known as
cardio-vocal syndrome.
We report our experience with seven cases of Ortners
syndrome due to thoracic aortic aneurysm with
compression of the left recurrent laryngeal nerve and
resultant hoarseness.
ortic Aneurysm, Thoracic
6.A curious case of Meckel’s diverticulum
Michael Arvind ; Benedict Dharmaraj ; Mohd Razali Ibrahim ; Jasjit Singh Nijhar ; Zainal Ariffin Azizi
The Medical Journal of Malaysia 2016;71(4):203-204
Meckel’s diverticulitis or Meckel’s associated pathology
frequently presents in childhood with gastrointestinal
bleeding. It is rarely seen in adults. It is a congenital
abnormality that commonly goes undetected. We present a
case of a perforated Meckel’s diverticulum due to fishbone
ingestion in an elderly gentleman. The aim of this case
report is to highlight the rare presentation of a perforation in
a Meckel’s diverticulum due to an extrinsic pathology and to
outline diagnostic and management options in cases of
Meckel’s diverticulum.
Meckel Diverticulum
7.Traumatic right proximal subclavian artery pseudoaneurysm treated with a hybrid procedure: A case report
Ismazizi Zaharudin ; Zainal Ariffin Azizi ; Naresh Govindarajanthran
The Medical Journal of Malaysia 2016;71(4):220-223
Blunt trauma to the right proximal subclavian artery is
uncommon and tends to be associated with
pseudoaneurysm formation. We report a patient with right
proximal subclavian artery pseudoaneurysm after blunt
chest trauma following a motor vehicle accident. The
condition was successfully treated with a combined
insertion of a covered stent and carotid-carotid bypass as a
hybrid procedure. Duplex scans at 6 month and 1 year
follow-up documented good stent-graft positioning and no
pseudoaneurysm recurrence.
Aneurysm, False
;
Subclavian Artery
8.Bleeding Jejunal GIST: An uncommon cause of Gastrointestinal Bleeding
Mohana Raj Thanapal ; Hanif Hussein ; Zainal Ariffin Azizi
The Medical Journal of Malaysia 2015;70(1):31-32
Gastrointestinal stromal tumours (GIST) are rare
gastrointestinal tumours and are one of the causes of
obscure gastrointestinal bleeding. We report a case of
massive gastrointestinal bleeding secondary to bleeding
jejunal GIST in a 43 years old gentleman. Endoscopic
intervention failed to identify the source of bleeding and CT
Angiography (CTA) showed a jejunal mass and patient
underwent laparotomy and resection of the bleeding jejunal
GIST. This article highlights the rare cause of the massive GI
bleeding and also emphasise the role of CTA in obscure GI
bleeding
Gastrointestinal Stromal Tumors
9.A Rare Cause of Pain in the Perineum
Syed Alwi Syed Abd ; Ariffin Azizi Zainal ; Lau Jia Him
The Medical Journal of Malaysia 2015;70(1):45-47
Isolated internal iliac aneurysms are rare. We report a case
of an uncommon presentation of perineal pain and
tenesmus in a man caused by the pressure effects of the
aneurysm. He had a successful endovascular exclusion and
thrombosis of his aneurysm. On follow up of more than 3
years he remains free of all symptoms and no recurrence of
the aneurysm.
Aneurysm
10.Giant Lipomatous Lesion of the Thigh With Retroperitoneal Extension: Case Series
Nan Chuang Khang ; Ahmad Rafizi Hariz ; Zainal Ariffin Azizi ; Ping Ching Chye
The Medical Journal of Malaysia 2014;69(6):273-274
Giant lipomatous lesions of the thigh swelling with
extension into retroperitoneum are rare. Lesions can be
malignant or benign and can have similar clinical
presentation. Treatments options differ and their prognosis
varies with histology. We present two cases of liposarcoma
and lipoma with the same clinical presentations that
underwent surgical resection.

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