ObjectiveTo construct an actor-network for integrating physical activity into rehabilitation services based on the World Health Organization Rehabilitation in Health Service System framework and actor-network theory (ANT). MethodsContent analysis was employed using the six building blocks of health service systems as the theoretical framework. Actors related to rehabilitation services were extracted and categorized into a rehabilitation actor pool, while a physical activity actor pool was formed based on four major physical activity scenarios. Actors from both pools were integrated, deduplicated and classified to form a final list of integrated actors. Using ANT, the construction process of the actor network integrating physical activity into rehabilitation was analyzed through the four stages of translation: problematization, interessment, enrollment and mobilization. ResultsA dynamic integration network was constructed, comprising human actors (patients, rehabilitation professionals, researchers, sports coaches, government departments, medical institutions, community organizations and industry media, etc.) and non-human actors (assistive devices, sports infrastructure, smart equipment, information systems, online exercise guidance systems, laws and regulations, strategic documents, and exercise prescriptions, etc.). The study identified maximizing rehabilitation outcomes as the mandatory passage point and elaborated on the critical role of government departments as focal actors in coordinating various stakeholders. ConclusionThe integration of physical activity into rehabilitation services is a dynamic network constructed by diverse actors through a process of translation. ANT provides an operational theoretical framework for cross-departmental governance of rehabilitation policies in China, promotes the spatial expansion of the rehabilitation field, and drives its transformation toward a networked and ecological system. The government needs to play a leading role in facilitating role reconstruction and synergy among heterogeneous actors in both the sports and rehabilitation sectors through mechanism design, to create a bidirectional empowerment mechanism that fosters mutual progress and ensures the sustainable development of integrated services.

ObjectiveTo delineate imaging findings using an imaging platform and investigate the correlation between MRI characteristics of spinal cord atrophy and clinical diagnosis in children with spinal cord injury (SCI). MethodsImaging data of 150 children with SCI admitted to Beijing Bo'ai Hospital, China Rehabilitation Research Center, from January, 2002 to March, 2024 were collected and imported into the imaging platform. The anteroposterior and transverse diameters of the middle part of the spinal cord at the cross-section with the most severe atrophy were measured, and the relevant indicators of the previous normal spinal cord segment were measured as controls; the radiomic features were extracted. Clinical data of the children including gender, age, cause of injury, sensory level, motor level, spinal cord injury level, injury severity and disease course were collected. ResultsSpinal cord atrophy was identified in 81 cases (54%), among which 78 cases (96%) were American Spinal Injury Association Impairment Scale (AIS) grade A and 3 cases (4%) were AIS grade C. The upper boundary of the spinal cord atrophy site strongly correlated with the injury level, motor level and sensory level (r > 0.8, P < 0.001). ConclusionMore than half of children with SCI may develop secondary spinal cord atrophy, the vast majority of whom suffer from complete spinal cord injury; the upper boundary of spinal cord atrophy is correlated with the injury level.

Purpose Chemical exchange saturation transfer(CEST)imaging is used to study the changes of glutamate metabolism in the hippocampus of rats with chronic unpredictable mild stress(CUMS)model,so as to evaluate the clinical reference value of glutamate acid CEST(GluCEST)imaging results.Materials and Methods Twenty-two male SD rats were enrolled,and were divided into CUMS and healthy groups.Rats in CUMS group were further divided into the non-treatment group(n=7)and the ketamine treatment group(n=8).Seven healthy rats were randomly selected as control group.CEST imaging scans were performed using 7T small animal magnetic resonance and glutamate concentrations were measured in both hippocampi.The difference of hippocampal GluCEST value and glutamate concentration between control group and CUMS non-treatment group,CUMS ketamine treatment group and CUMS non-treatment group was analyzed,respectively.Results Compared with the control group,the hippocampal GluCEST value in CUMS non-treatment group was increased(left:t=2.8,P=0.015;right:t=3.0,P=0.011),while the hippocampal GluCEST value of rats in CUMS ketamine treatment group was decreased compared with CUMS non-treatment group(left:t=2.3,P=0.037;right:t=2.5,P=0.028).Conclusion GluCEST imaging can provide high spatial resolution images and accurately evaluate the changes of glutamate metabolism in hippocampus of rats with depression,which is conducive to monitoring the abnormal signals of hippocampal neurons caused by depression.

Objective:To explore the predictive value of inflammatory factors and renal function indicators for diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM) and their risk factors.Methods:A total of 106 T2DM patients admitted to the General Hospital of PLA Northern Theater Command from March 2022 to February 2024 were prospectively selected. They were divided into the DR group (31 cases) and non-DR group (75 cases) according to the presence or absence of DR. Binary logistic regression analysis was used to screen the influencing factors of DR in T2DM patients, and receiver operating characteristic (ROC) curve was used to analyze the predictive value of inflammatory factors and renal function indicators for DR in T2DM patients.Results:Univariate analysis showed that T2DM duration, smoking, hypertension, blood urea, serum creatinine, serum uric acid, interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and C-reactive protein (CRP) were associated with DR in T2DM patients (all P<0.05). Multivariate logistic regression analysis showed that TNF-α, serum creatinine, serum uric acid, and T2DM duration were independent risk factors for DR in T2DM patients (all P<0.05), which could increase the risk by 1.724 times, 1.038 times, 1.026 times, and 4.904 times, respectively. ROC curve analysis showed that the areas under the curve (AUC) of TNF-α, serum creatinine, and serum uric acid for predicting DR in T2DM patients were 0.906, 0.842, and 0.809, respectively. Conclusions:TNF-α, serum creatinine, serum uric acid, and T2DM duration are independent risk factors for DR in T2DM patients. TNF-α, serum creatinine, and serum uric acid have good predictive value for DR in T2DM patients, and can be used as clinical predictive indicators to provide references for early identification of high-risk patients and formulation of DR prevention and treatment strategies.

Objective To establish an expert consensus on home exercise for prevention and rehabilitation of breast cancer related lymphedema.Methods Evidence-based nursing method was used to systematically retrieve and evaluate relevant studies in databases and guideline networks,with a search period from the establishment of the databases to October 2023.Evidence was synthesized to form the expert consensus draft after literature screening,quality evaluation,evidence extraction and evidence integration.Then the final draft was formed through expert discussion meeting and 2 rounds of expert letter consultation.Results The consensus includes 5 dimensions with a total of 22 items,involving evaluation of home exercise,management of home exercise,principles of home exercise,program of home exercise and significance of home exercise.Conclusion This"consensus"was constructed in a scientific and rigorous way,and can provide guidance for promoting the home exercise for prevention and rehabilitation of breast cancer related lymphedema,and ensure the safe and effective implementation of home exercise rehabilitation.

Objective:To explore the predictive value of inflammatory factors and renal function indicators for diabetic retinopathy (DR) in patients with type 2 diabetes mellitus (T2DM) and their risk factors.Methods:A total of 106 T2DM patients admitted to the General Hospital of PLA Northern Theater Command from March 2022 to February 2024 were prospectively selected. They were divided into the DR group (31 cases) and non-DR group (75 cases) according to the presence or absence of DR. Binary logistic regression analysis was used to screen the influencing factors of DR in T2DM patients, and receiver operating characteristic (ROC) curve was used to analyze the predictive value of inflammatory factors and renal function indicators for DR in T2DM patients.Results:Univariate analysis showed that T2DM duration, smoking, hypertension, blood urea, serum creatinine, serum uric acid, interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and C-reactive protein (CRP) were associated with DR in T2DM patients (all P<0.05). Multivariate logistic regression analysis showed that TNF-α, serum creatinine, serum uric acid, and T2DM duration were independent risk factors for DR in T2DM patients (all P<0.05), which could increase the risk by 1.724 times, 1.038 times, 1.026 times, and 4.904 times, respectively. ROC curve analysis showed that the areas under the curve (AUC) of TNF-α, serum creatinine, and serum uric acid for predicting DR in T2DM patients were 0.906, 0.842, and 0.809, respectively. Conclusions:TNF-α, serum creatinine, serum uric acid, and T2DM duration are independent risk factors for DR in T2DM patients. TNF-α, serum creatinine, and serum uric acid have good predictive value for DR in T2DM patients, and can be used as clinical predictive indicators to provide references for early identification of high-risk patients and formulation of DR prevention and treatment strategies.

Objective To analyze the literature on acupuncture and moxibustion in promoting regeneration and repair published at home and abroad based on bibliometrics to identify the current status,hotspots,and trends of research in this field.Methods Chinese and English literature related to acupuncture and moxibustion in promoting regeneration and repair published in China Knowledge Network(CNKI)and Web of Science(WOS)Core Collection were visualized and analyzed using VOSviewer and Citespace software.Results Since the inception of the database to June 30,2024,1651 and 1437 documents were published in Chinese and English,respectively,showing a fluctuating upward trend over the past 20 years,with China being the country with the highest number of publications,Heilongjiang University of Traditional Chinese Medicine being the research institution with the highest number of publications in the CNKI database,and Beijing University of Traditional Chinese Medicine and Shanghai University of Traditional Chinese Medicine being the research institutions with the highest number of publications in the WOS database.The keyword analysis revealed that the research hotspot of acupuncture and moxibustion in promoting regeneration and repair focused on acupuncture therapies based on electroacupuncture,acupuncture and moxibustion,as well as research targets based on the brain,spinal cord and gastrointestinal mucosa,and the future research trend would be centered on the mechanism of action,focusing on the value of more acupuncture therapies in diseases such as spinal cord injury and ulcerative colitis.Conclusion In recent years,the research field of acupuncture and moxibustion in promoting regeneration and repair has developed rapidly,and various research teams have achieved rich results.The research hotspots have shown a diversified and deeper trend,and the application of acupuncture and moxibustion in promoting regeneration and repair has a broad prospect,and it is expected to provide more effective therapeutic means for the clinic.

Objective To develop a new cardiac rehabilitation exercise program based on the LEARNS health education model for patients undergoing percutaneous coronary intervention(PCI),and to evaluate its effectiveness.Methods A total of 78 inpatients with acute coronary syndrome(ACS)who received PCI between February and May 2024 in a tertiary hospital were enrolled.Using a random number table,participants were assigned to either an intervention group or a control group(n=39 each).The control group received routine health education,while the intervention group received a cardiac rehabilitation exercise program developed based on the LEARNS model.The intervention started during hospitalization and lasted for two weeks.After the intervention,patients'willingness to participate in Phase II cardiac rehabilitation,exercise self-efficacy and exercise behavior,were evaluated.Results All 76 patients completed the study.After the intervention,the intervention group showed significantly higher scores in willingness to participate in rehabilitation(P<0.001)and exercise self-efficacy(P<0.001)compared with the control group.In terms of exercise behaviors,the intervention group also performed better than the control group,with statistically significant differences across related indicators(P<0.05).Conclusion The application of a new PCI postoperative rehabilitation program based on the LEARNS health education model can significantly enhance patients'willingness to participate in Phase II cardiac rehabilitation,improve their exercise self-efficacy and behavior,and effectively promote the implementation and sustainability of cardiac rehabilitation.

Objective To develop a new cardiac rehabilitation exercise program based on the LEARNS health education model for patients undergoing percutaneous coronary intervention(PCI),and to evaluate its effectiveness.Methods A total of 78 inpatients with acute coronary syndrome(ACS)who received PCI between February and May 2024 in a tertiary hospital were enrolled.Using a random number table,participants were assigned to either an intervention group or a control group(n=39 each).The control group received routine health education,while the intervention group received a cardiac rehabilitation exercise program developed based on the LEARNS model.The intervention started during hospitalization and lasted for two weeks.After the intervention,patients'willingness to participate in Phase II cardiac rehabilitation,exercise self-efficacy and exercise behavior,were evaluated.Results All 76 patients completed the study.After the intervention,the intervention group showed significantly higher scores in willingness to participate in rehabilitation(P<0.001)and exercise self-efficacy(P<0.001)compared with the control group.In terms of exercise behaviors,the intervention group also performed better than the control group,with statistically significant differences across related indicators(P<0.05).Conclusion The application of a new PCI postoperative rehabilitation program based on the LEARNS health education model can significantly enhance patients'willingness to participate in Phase II cardiac rehabilitation,improve their exercise self-efficacy and behavior,and effectively promote the implementation and sustainability of cardiac rehabilitation.

Objective:To understand the current status of epidemiological investigation task force construction and the performance of infectious disease epidemic response in county (district) Centers for Disease Control and Prevention (CDCs) in China, analyze the influencing factors and provide scientific evidence to improve the construction of grassroot epidemiological investigation task force.Methods:A survey was conducted in epidemiological investigation staff in county (district) CDCs in 31 provinces (autonomous regions/municipalities) and Xinjiang Production and Construction Corps in China. A self-designed questionnaire was used to collect information based on the epidemiological dynamic data collection platform of China CDC. A descriptive epidemiological analysis was conducted, and multiple linear regression models were used to identify the factors associated with the performance of infectious disease epidemic response.Results:A total of 24 934 epidemiological investigation task force members from 2 897 county (district) CDCs were surveyed in the study. In the epidemiological investigation task force, women, those with bachelor's degree and public health workers accounted for 62.46%, 71.36%, and 49.05% respectively. Up to 91.72% of the task force members had participated in field epidemic response. The average score of awareness of epidemic investigation procedures was 60.00, while the average score of key skill proficiency in the investigation was 42.22. The epidemic response performance showed correlations with area, gender, age, education level, major, and field epidemiology training programs, those who had received longer training showed higher competency scores (all P<0.001). Conclusions:Progress has been made in the construction of epidemiological investigation task force in grass-root CDCs in China, but further improvements are needed, especially in the knowledge awareness and investigation skills of the task force. Field epidemiology training demonstrated substantial impact on the improvement of epidemic response performance, indicating that it is necessary to further strengthen the training in grassroot public health workers for the better response to infectious disease epidemics.