1.Propensity score matched comparison of pancreatoduodenectomy with pancreatogastrostomy versus pancreatojejunostomy: A single institution experience shifting from pancreatogastrostomy to pancreatojejunostomy
Teik Wen LIM ; Sabrina Hui Xian CHEOK ; Yvette CHONG ; Darren Weiquan CHUA ; Ek Khoon TAN ; Jin Yao TEO ; Ye-Xin KOH ; Peng Chung CHEOW ; Pierce Kah Hoe CHOW ; London Lucien Peng Jin OOI ; Alexander Yaw Fui CHUNG ; Brian Kim Poh GOH
Annals of Hepato-Biliary-Pancreatic Surgery 2026;30(1):91-98
Background:
s/Aims: Postoperative pancreatic fistulas (POPF) remain a major cause of morbidity and mortality following pancreatoduodenectomy (PD). Pancreatogastrostomy (PG) and pancreatojejunostomy (PJ) are the two most commonly used reconstruction techniques, yet evidence favoring one over the other is inconclusive. This study evaluates postoperative outcomes following open PD at a single institution that transitioned from PG to PJ as the preferred reconstruction method.
Methods:
This retrospective comparative study included patients who underwent PD between April 2005 and August 2022. Of 757 patients identified, 522 met the inclusion criteria. Propensity score matching (PSM) was performed to adjust for clinically relevant covariates. Primary endpoints were clinically relevant (CR) POPF (grade B/C) and Clavien–Dindo (CD) grade ≥ 3 POPFs. Secondary outcomes included post-pancreatectomy hemorrhage (PPH), delayed gastric emptying (DGE), systemic complications, length of hospital stay, and mortality.
Results:
Overall, CR-POPF and CD grade ≥ 3 POPFs occurred in 21.3% and 8.0% of patients, respectively. Thirty-day and in-hospital mortality rates were 3.1% and 4.2%. After PSM, 368 patients (184 PG and 184 PJ) were analyzed. Grade B POPFs were more frequent following PJ than PG (24.5% vs. 15.8%, p < 0.001). Although CR-POPF and CD grade ≥ 3 POPFs were numerically higher in the PJ group, differences were not statistically significant. In contrast, DGE, PPH, and in-hospital mortality were significantly higher following PG (37.0% vs. 25.0%, p = 0.025; 16.3% vs. 8.7%, p = 0.025; and 7.6% vs. 2.7%, p = 0.049, respectively).
Conclusions
PG was associated with a lower incidence of grade B POPFs but higher rates of DGE, PPH, and in-hospital mortality.
2.Ectopic schistosomiasis presenting as ruptured appendicitis with periappendiceal abscess formation: An alternative pathogenetic perspective
Marcel Joshua del Fierro ; Yvette Tan ; Larissa Lara Torno
Philippine Journal of Pathology 2022;7(1):53-56
Schistosomiasis is still a public health burden in the Philippines. Chronic infection with Schistosoma japonicum, the only species endemic in the Philippines, clinically manifests itself in a wide variety of pathologies usually correlated with the anatomical site of adult worm activity and deposition of eggs. One of the documented ectopic sites for Schistosoma ova is the appendix. A rare sequela of this is acute appendicitis and an even rarer consequence is progression to appendiceal rupture leading to acute peritonitis. We present a case of a 27-year-old Filipino residing in Davao City but born in Agusan Province who initially complained of right lower quadrant abdominal pain but presented at the emergency room with generalized abdominal tenderness with signs of peritoneal irritation. Exploratory laparotomy with an infraumbilical incision revealed ruptured appendicitis with periappendiceal abscess formation and appendectomy was subsequently done. Schistosoma infection of the appendix was subsequently established by histopathological analysis. Furthermore, features observed suggest an atypical pathogenetic process contrary to the putative pathogenesis of most cases of acute appendicitis.
Schistosomiasis
;
Schistosoma japonicum
3.The wandering twin: A case of a uterine didelphys with the obstructed hemiuteri in the anterior abdominal wall
Nina Patricia A. Gaerlan-Revecho ; Yvette Marie C. Manalo-Mendoza ; Anna Katrina G. Purugganan ; Delfin A. Tan
Philippine Journal of Reproductive Endocrinology and Infertility 2017;14(1):5-10
Mullerian duct anomalies (MDAs) are congenital defects of the female genital system that arise
from abnormal embryological development of the Mullerian ducts. A didelphys uterus, also
known as a "double uterus," is one of the least common amongst the MDAs. Reported here
is a case of a 16 year old female with a uterus didelphys with the obstructed left hemiuteri
adherent in the anterior abdominal wall, and an endometriotic cyst on the same side. She
underwent hysteroscopy-guided vaginoscopy, laparoscopic left hemihysterectomy, left
oophorocystectomy. Cases such as these require careful preoperative planning and
diagnostic imaging for more accurate diagnosis and, hence, for the most appropriate surgical
procedure to be carried out. 3D ultrasonography and Magnetic Resonance Imaging have
been the most widely used imaging techniques. The goals of management are to relieve the
symptoms of obstruction and to restore the normal anatomy as much as possible in order to
provide the best chance for future fertility.
Uterine Didelphys


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