1.Prevalence of Erectile Dysfunction and Its Associated Factors among Non-Diabetic Overweight & Obese Patients Attending Government Health Clinics in Kuantan, Pahang
Che&rsquo ; Man M ; Mohd Zainal AZAR ; Yusof MZ
The International Medical Journal Malaysia 2026;25(No. 2):38-46
INTRODUCTION: In the clinical setting, erectile dysfunction (ED) is a significant issue
that should not be neglected, as it can adversely impact the quality of life of patients
and their partners, especially among overweight and obese populations. This study
aims to determine the prevalence of ED and its associated factors among non-diabetic,
overweight, and obese patients who attend a government health clinic in Kuantan,
Pahang, Malaysia. MATERIALS AND METHODS: A six-month cross-sectional study
was conducted from February 2024 to August 2024 at twelve health clinics in
Kuantan, Pahang. The selected respondents were married men over 18 years old, and
those with diabetes mellitus, cardiovascular disease, psychiatric illness, or illiteracy were
excluded. Data were collected using the validated Malay version of the International
Index of Erectile Function (IIEF-5). ED was defined as an IIEF-5 score of less than
22. Descriptive analysis and simple and multiple logistic regression were performed
using SPSS. RESULTS: All 221 eligible patients in the study responded (100% response
rate). The prevalence of ED was 66.1% (n=146). Multiple logistic regression
showed that ED was significantly associated with dyslipidemia [AOR (95% CI): 2.42
(1.06–5.52); p-value=0.036], anxiety [AOR (95% CI): 3.99 (1.44–11.01);
p-value=0.008] and older age [AOR (95% CI): 1.07 (1.02–1.12); p-value=0.009].
CONCLUSION: The study revealed a high prevalence of ED among non-diabetic
overweight and obese patients, potentially linked to increasing age, dyslipidemia, and
anxiety. Increasing awareness among the public and healthcare providers could
improve detection rates in primary care.
2.Arabic Language and Medical Terminology in Education: A Systematic Review
Mior Syazril Mohamed Sapawi ; Nik Mohd Rahimi Nik Yusof
The International Medical Journal Malaysia 2026;25(No. 1):41-52
The use of Arabic in medical education and healthcare communication remains limited despite growing linguistic needs in Arabic-speaking populations. Issues related to translation accuracy, cultural sensitivity, and curriculum alignment hinder its integration. The objective of this study is to systematically review how Arabic medical terminology has been translated, validated, and applied in educational and clinical contexts. This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) 2020 guidelines. Searches were conducted in May 2025 across three databases: Scopus, Web of Science (WoS), and the Education Resources Information Center (ERIC). A total of 769 records were retrieved, and 19 peer-reviewed articles were selected based on inclusion criteria. A six-point quality appraisal framework was applied to ensure methodological rigour prior to thematic synthesis. Three major themes emerged: (1) translation and cultural adaptation, highlighting the importance of expert validation and semantic accuracy; (2) psychometric evaluation, where tools such as the Postgraduate Hospital Educational Environment Measure (PHEEM) demonstrated strong internal consistency and contextual clarity; and (3) educational application, showing varied success in enhancing communication, comprehension, and learner confidence. Gaps in terminology standardisation and the limitations of automated translation tools were noted across studies. In conclusion Arabic medical terminology, when supported by structured processes and expert review, makes a meaningful contribution to education and communication. Further efforts should prioritise the development of validated terminology repositories, multidisciplinary collaboration, and the integration of Arabic-language resources into medical curricula to support inclusive and patient-centred care.
3.An Evidence-Based Treatment Guide for Trauma from Occlusion: Essential Guidelines for Dental Students
Nor Zety Mohd Noh ; Nurul Ain Mohamed Yusof
Annals of Dentistry 2025;32(No. 1):40-47
An Evidence-Based Treatment Guide for Trauma from Occlusion: Essential Guidelines for Dental Students
Trauma resulting from occlusion is a common clinical issue that can lead to significant discomfort, dysfunction, and long-term dental complications. This article is designed to offer a simplified, evidence-based overview of the pathophysiology of occlusal trauma, diagnostic approaches, and a treatment guide, making the management of occlusal trauma more accessible and easier to understand. Emphasis is placed on the importance of an individualized treatment planning, offering clinicians practical insights to optimize outcomes and minimize the adverse effects. The findings support the need for evidence-based decision-making in the management of occlusal trauma, ensuring both short-term relief and long-term dental health preservation.
5.Influence of Different Types of Contralateral Suppression Tones on Otoacoustic Emission in Children With Autism Spectrum Disorder
Fatin Nabilah JAMAL ; Ahmad Aidil Arafat DZULKARNAIN ; Nadzirah Ahmad BASRI ; Sarah RAHMAT ; Fatin Amira SHAHRUDIN ; Mohd. Zulfaezal Che AZEMIN ; Shahrul Na’im SIDEK ; Hazlina Md YUSOF ; Siti Rafiah Abd. HAMID
Journal of Audiology & Otology 2025;29(1):49-56
Background and Objectives:
Auditory sensory gating deficits are abnormalities in patients with autism spectrum disorder (ASD) that may lead to sensory processing difficulties. It is particularly difficult for children with ASD to distinguish multiple auditory stimuli, which hinders them from focusing on a single auditory stimulus and separating unnecessary sounds. Suppression of otoacoustic emission (OAE) is an approach used to identify sensory gating deficits in the general population, specifically for children with ASD. This study aimed to investigate the suppression effect of various types of sound suppressors to measure their sensory gating capacity in children with ASD.
Subjects and Methods:
Twenty children including 10 with ASD and 10 normally developing children aged 6-12 years were recruited for this study. One accessible ear was exposed to transient-evoked OAE, whereas the other was exposed to suppressor tones. Contralateral suppressors included white noise, Quranic recitations, environmental noise, and natural sound. The magnitude of OAE suppression was determined from the difference between the OAE amplitude with and without the masker (in dB sound pressure levels) for all sound types. The sound with the highest suppression effect was determined using effect size calculation and repeated-measures analysis of variance at a 95% confidence level. A high suppression effect may suggest a high sensory gating performance, whereas low suppression may indicate low sensory gating performance.
Results:
Based on the analysis, the sound with the highest suppression effect was that of the waterfall. The suppression results were supported by descriptive analysis findings and effect-size calculations.
Conclusions
This study provides a better understanding of the alternative sound stimuli, besides the standard white noise tone, for the assessment of sensory gating deficits among children with ASD. Sounds with a high suppression effect have the potential to be used as sound therapy interventions for children with ASD as part of rehabilitation and therapy.
6.Influence of Different Types of Contralateral Suppression Tones on Otoacoustic Emission in Children With Autism Spectrum Disorder
Fatin Nabilah JAMAL ; Ahmad Aidil Arafat DZULKARNAIN ; Nadzirah Ahmad BASRI ; Sarah RAHMAT ; Fatin Amira SHAHRUDIN ; Mohd. Zulfaezal Che AZEMIN ; Shahrul Na’im SIDEK ; Hazlina Md YUSOF ; Siti Rafiah Abd. HAMID
Journal of Audiology & Otology 2025;29(1):49-56
Background and Objectives:
Auditory sensory gating deficits are abnormalities in patients with autism spectrum disorder (ASD) that may lead to sensory processing difficulties. It is particularly difficult for children with ASD to distinguish multiple auditory stimuli, which hinders them from focusing on a single auditory stimulus and separating unnecessary sounds. Suppression of otoacoustic emission (OAE) is an approach used to identify sensory gating deficits in the general population, specifically for children with ASD. This study aimed to investigate the suppression effect of various types of sound suppressors to measure their sensory gating capacity in children with ASD.
Subjects and Methods:
Twenty children including 10 with ASD and 10 normally developing children aged 6-12 years were recruited for this study. One accessible ear was exposed to transient-evoked OAE, whereas the other was exposed to suppressor tones. Contralateral suppressors included white noise, Quranic recitations, environmental noise, and natural sound. The magnitude of OAE suppression was determined from the difference between the OAE amplitude with and without the masker (in dB sound pressure levels) for all sound types. The sound with the highest suppression effect was determined using effect size calculation and repeated-measures analysis of variance at a 95% confidence level. A high suppression effect may suggest a high sensory gating performance, whereas low suppression may indicate low sensory gating performance.
Results:
Based on the analysis, the sound with the highest suppression effect was that of the waterfall. The suppression results were supported by descriptive analysis findings and effect-size calculations.
Conclusions
This study provides a better understanding of the alternative sound stimuli, besides the standard white noise tone, for the assessment of sensory gating deficits among children with ASD. Sounds with a high suppression effect have the potential to be used as sound therapy interventions for children with ASD as part of rehabilitation and therapy.
7.Influence of Different Types of Contralateral Suppression Tones on Otoacoustic Emission in Children With Autism Spectrum Disorder
Fatin Nabilah JAMAL ; Ahmad Aidil Arafat DZULKARNAIN ; Nadzirah Ahmad BASRI ; Sarah RAHMAT ; Fatin Amira SHAHRUDIN ; Mohd. Zulfaezal Che AZEMIN ; Shahrul Na’im SIDEK ; Hazlina Md YUSOF ; Siti Rafiah Abd. HAMID
Journal of Audiology & Otology 2025;29(1):49-56
Background and Objectives:
Auditory sensory gating deficits are abnormalities in patients with autism spectrum disorder (ASD) that may lead to sensory processing difficulties. It is particularly difficult for children with ASD to distinguish multiple auditory stimuli, which hinders them from focusing on a single auditory stimulus and separating unnecessary sounds. Suppression of otoacoustic emission (OAE) is an approach used to identify sensory gating deficits in the general population, specifically for children with ASD. This study aimed to investigate the suppression effect of various types of sound suppressors to measure their sensory gating capacity in children with ASD.
Subjects and Methods:
Twenty children including 10 with ASD and 10 normally developing children aged 6-12 years were recruited for this study. One accessible ear was exposed to transient-evoked OAE, whereas the other was exposed to suppressor tones. Contralateral suppressors included white noise, Quranic recitations, environmental noise, and natural sound. The magnitude of OAE suppression was determined from the difference between the OAE amplitude with and without the masker (in dB sound pressure levels) for all sound types. The sound with the highest suppression effect was determined using effect size calculation and repeated-measures analysis of variance at a 95% confidence level. A high suppression effect may suggest a high sensory gating performance, whereas low suppression may indicate low sensory gating performance.
Results:
Based on the analysis, the sound with the highest suppression effect was that of the waterfall. The suppression results were supported by descriptive analysis findings and effect-size calculations.
Conclusions
This study provides a better understanding of the alternative sound stimuli, besides the standard white noise tone, for the assessment of sensory gating deficits among children with ASD. Sounds with a high suppression effect have the potential to be used as sound therapy interventions for children with ASD as part of rehabilitation and therapy.
8.Protective Effects of Tualang Honey on the Testes of Rats Subjected to Chronic Combined Stress
Faizah Md Nawi ; Mohd Asnizam Asari ; Haziq Hazman Norman ; Nurul Aiman Mohd Yusof ; Mohamad Syabil Ikhwan Mohd Amin
Malaysian Journal of Medicine and Health Sciences 2024;20(No.2):34-41
Introduction: Persistent exposure to stress can lead to a wide range of pathological effects, including reproductive
dysfunctions. Tualang honey, renowned for its antioxidant properties has been utilised in traditional and modern
medicine. This study aims to investigate the protective effects of Tualang honey against stress-induced testicular
damage in male rats. Method: Twenty-four male rats were divided into control group, stress-exposed group, Tualang-honey-supplemented group and stress-exposed with Tualang-honey-supplemented group. Restraint stress test
(RST) and Forced swimming test (FST) were imposed on the rats for 21 days. Serum testosterone and corticosterone
concentration were measured using ELISA. Testes were harvested, weighed, processed and stained for spermatid
counts and measuring seminiferous epithelial height and diameter. One-way analysis of variance (ANOVA) was
used to compare the numerical data between groups. Results: The testosterone concentration, spermatid count,
seminiferous epithelial height and diameter in stress group were significantly lower compared to control group (p <
0.05). Corticosterone concentration was significantly greater in the stress group than in the control group. The spermatid count and seminiferous epithelial height and diameter of honey-treated groups were significantly higher than
the stress-only group (p < 0.05). The corticosterone concentration of honey-treated groups was significantly higher
compared to the stress-only group. Meanwhile, the testosterone concentration of honey-treated groups was higher
than the stress-only group although the results were insignificant. Conclusion: Tualang honey has the potential to
ameliorate corticosterone concentration and induce morphological alterations by increasing spermatid counts and
seminiferous epithelial thickness and diameter in rat testes exposed to prolonged stress.
9.Survival Analysis and Prognostic Factors for Peri-ocular Malignancies in Malaysia
Dhashani Sivaratnam ; Radzlian Othman ; Navin Kumar Devaraj ; Yap Ming Teck ; Vincent Ng Teng Fung ; Ew Shao Chen ; Ramizah Md Rozi ; Nur Najlaa Baharudin ; Kirbashini Kanasan ; Abdul Hanif Khan Yusof Khan ; Vasudevan Ramachandran ; Siew Moi Ching
Malaysian Journal of Medicine and Health Sciences 2024;20(No.1):60-69
Introduction: This study aims to determine the prognostic factors and survival outcomes of patients that underwent
this surgery. Method: A retrospective review of 43 patients who underwent exenteration for periocular malignancies
over a 14-year period was carried out. Patient demographics, tumour histology, treatment details, surgical margins’
status and post-operative survival were recorded. The survival outcome examined was the overall survival (OS)
rate. Cox regression and Kaplan-Meier analysis were used to evaluate post-exenteration survival. Results: In total,
20 females and 23 males with a median age of 62 ± 17.3 years were identified. The most common indication for
exenteration was basal cell carcinoma (20.9%), followed by squamous cell carcinoma (18.6%), adenocystic carcinoma (14%), malignant melanoma (14%) and sebaceous gland carcinoma (11.6%). The independent predictors for
worse OS on multivariate analysis were Chinese ethnicity (adjusted hazard ratio [aHR] 4.95, p =0.017), sebaceous
gland carcinoma (aHR 57.61 p=0.006), adenocystic carcinoma (aHR 45.87, p=0.008), clear surgical margins (aHR
5.41, p=0.025), receiving only chemotherapy (aHR 169.13, p=0.004), and receiving both adjuvant chemotherapy
and radiotherapy (aHR 41.51, p=0.010). Conclusion: We recommend targeted public health initiatives for Chinese
patients due to their increased mortality risk from peri-ocular malignancies. In addition, we advise comprehensive
adjuvant therapy for all patients regardless of whether a clear surgical margin is achieved. Basal cell carcinoma and
adenocystic carcinoma may also benefit from genetic research. We advocate more training for ophthalmologists to
identify periocular malignancies earlier for better treatment options and increased chances of survival.
10.Modulation Agents of Wound Healing in Ocular Surgeries
Yaakub Azhany ; Mohd-Yusof Siti-Fairuz ; Azlina Ahmad ; Wan Nazirah Wan Yusuf ; Low Jen Hou ; Ahmad-Tajudin Liza-Sharmini ; Jemaima Che Hamzah
Malaysian Journal of Medicine and Health Sciences 2024;20(No.1):293-303
Wound healing is a complex process that includes haemostasis and inflammation, followed by a proliferation period and repair and finally remodelling. Ocular surgeries, particularly in glaucoma cases, aim at minimal fibrosis to preserve the function of trabeculectomy as an alternative pathway for aqueous drainage. Hence, it is important to find an agent to modulate the wound healing process. This review presents compilation of wound modulation agents that have been tested in vitro, in vivo, or clinically on patients undergoing ocular surgeries, particularly for glaucoma. We identified agents into four groups, mostly for glaucoma filtration operations: anti-metabolites, anti-growth factors, mechanical barriers and rho kinases. The effect of these agents is highlighted in this review. In conclusion,
despite recognized drawbacks of antimetabolites, they are still regarded as the gold standard and the most efficient treatment as anti-scarring agents use in ocular surgeries. More studies are needed to inquire agents that efficient yet has minimal adverse effects both in short and long term.


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