Nocturnal enuresis (NE) is a common pediatric disease with unclear pathogenesis.The prevailing hypothesis is that NE is caused by a discrepancy between nocturnal urine output and bladder capacity and sleep-wake disturbances.Monosymptomatic nocturnal enuresis (MNE) with nocturnal polyuria is a common subtype of NE, which can be effectively treated by Desmopressin.However, it is possible that some children may demonstrate an inability to respond favorably to this form of therapy and become resistant to it, which significantly impacts their physical and mental health and overall quality of life.In this article, recent advances in the pathogenesis and treatment of Desmopressin-resistant MNE with nocturnal polyuria in children were reviewed to provide a reference for its treatment.

Nocturnal enuresis (NE) is a common pediatric disease with unclear pathogenesis.The prevailing hypothesis is that NE is caused by a discrepancy between nocturnal urine output and bladder capacity and sleep-wake disturbances.Monosymptomatic nocturnal enuresis (MNE) with nocturnal polyuria is a common subtype of NE, which can be effectively treated by Desmopressin.However, it is possible that some children may demonstrate an inability to respond favorably to this form of therapy and become resistant to it, which significantly impacts their physical and mental health and overall quality of life.In this article, recent advances in the pathogenesis and treatment of Desmopressin-resistant MNE with nocturnal polyuria in children were reviewed to provide a reference for its treatment.

A total of 38 cases of senile brucella spondylitis disease at our hospital during January 2002 and March 2012 were analyzed .After admission , all of them were definitely diagnosed on the basis of epidemiological history , clinical manifestations , laboratory tests , imaging and pathological examinations . Over a follow-up period of 12 months, 17 cases were cured after standardized drug treatment .Among 21 surgical cases, there were curing (n=17) and improving (n=2).Senile brucellosis spondylitis has distinct serological and pathological characteristics .And formulating the diagnostic criteria may improve its diagnostic rate and reduce its misdiagnostic rate .And standardized drug therapy achieves a better curing rate and a proper timing of surgical intervention improves its clinical outcomes .

Objective To explore the value of the multi-phasic spiral CT scan in the diagnosis of gallbladder carcinoma.Methods The characteristic CT findings were reviewed in 42 cases with gallbladder carcinoma proven pathologically.Results The gall bladder carcinoma had certain enhancing characteristics: high density in hepatic artery period,same or high density in porch vein period,and no clear fadeaway in delaying period.In other words,the gall bladder carcinoma was higher enhancement than normal gallbladder wall and liver,and had long-term enhancement.Conclusion The multi-phasic spiral CT scan plays an important role in diagnosis and differential diagnosis of gallbladder carcinoma.