As a pair of core categories in traditional Chinese philosophy， "xiang （manifestation）" and "xing （physique）" together construct a cognitive paradigm distinct from the western subject-object dichotomy. Both originate from the common ontological foundation of "qi" ， exhibiting a dialectical unity between "xiang" which is characterized by change， virtuality， and functionality， and "xing" which is characterized by determinacy， substance， and structure. Their relationship achieves profound unity through shared origins， mutual transformation， and interdependence as substance and function. This dialectical "xiang-xing" paradigm is deeply embedded in the theoretical system of traditional Chinese medicine （TCM）. It is reflected in the multi-layered construction of visceral manifestation theory， the cognitive approach of "inferring the viscera through manifestation" ， the clinical practice of "treating the physique by observing the manifestation"， and the academic feature of "emphasizing qi and body， unifying body and qi". Looking to the future， the "xiang-xing" paradigm can not only provide a philosophical foundation and methodological guidance for the modernization of TCM theory and the integration of Chinese and western medicine， but also demonstrate unique practical value in areas such as clinical precision diagnosis and treatment， innovative development and quality control of Chinese herbal medicine. Therefore， it can promote the creative transformation and innovative deve-lopment of TCM， and contribute holistic and dynamic Chinese wisdom to contemporary life sciences.

China is currently in an accelerated stage of population aging, and brain diseases pose a significant threat to the health of the elderly. " Preventing brain aging and maintaining brain health" has become a high-level goal of healthy aging. During the process of aging, the physiological and psychological states of elderly people change, making them prone to nervousness and exhaustion, which can disturb the brain spirit, damage the brain collaterals, and severely endanger brain health. Starting from the holistic view of cultivating both body and spirit in traditional Chinese medicine, based on the physical and mental characteristics of the elderly, this paper applies the concept and method of " relaxation and tranquility" in the protection of elderly brain health, focusing on maintaining relaxation and tranquility in both physical and mental aspects. Specific measures include emphasizing subjective consciousness, relaxing the heart and calming down; utilizing the daoyin method, relaxing the body and calming down, combining relaxation and tranquility, cultivating both body and spirit to prevent diseases and protect the brain, which enables the elderly to have a healthy mind and body, a sense of happiness and fulfillment, and to age gracefully. Simultaneously, advocating for tranquility is also called " respect" for relaxation, following nature to understand constant changes, and improving one′s ability to think positively in old age, in order to expand ideas for the protection of elderly brain health.

The evolving health demands of contemporary society urgently call for adaptive adjustments in health policies and a comprehensive enhancement of perspectives， horizons， and viewpoints. Grounded in the solid foundation of traditional Chinese culture， this paper proposed a multidimensional evaluation system for assessing the health status of modern China's ideal life. Drawing upon the philosophical insights of Confucianism， Daoism， Mohism， Song-Ming Neo-Confucianism， and their subsequent developments， as well as core cultural values such as harmony （和）， happiness （福）， and joy （乐）， this system established a fundamental framework for evaluating health in modern ideal life. The framework consists of eight indices， i.e. harmony index， diligence index， peace of mind index， happiness index， compassion index， innovation index， fulfillment index， and adaptability index. The purpose of constructing this system is to comprehensively and deeply reflect the physical and mental characteristics and behavioral patterns of the Chinese population， and to provide a holistic evaluation framework for advancing the foundation of health in modern ideal life， offering solid scientific support for formulating health policies that align with China's national context.

The Chinese medicine Zha Gui,the senior manager of traditional Chinese medicine dispensing,plays an important role and key function in the"front store and back factory"Chinese medicine pharmacy.Inheriting the valuable experience and excellent culture of Chinese medicine Zha Gui is of great academic value and practical significance in clarifying the development of the discipline of traditional Chinese medicine,standardizing the technical operation of traditional Chinese medicine preparation,and promoting the"living inheritance"of the old pharmacist's skills.At the start of the new era and opening up to new thinking,this paper examined the rise of old Chinese medicine stores and Chinese medicine Zha Gui,analyzed the post responsibility,inheritance path and future development of Chinese medicine Zha Gui,and put forward the strategy of cultivating high-quality Chinese medicine Zha Gui talents,aiming at cultivating compound innovative talents in the traditional Chinese medicine industry in line with the needs of the contemporary society.

This paper explored the significance and value of building a doctor-patient narrative community in clinical practice.It was clarified that clinical practice guided by evidence-based medicine thinking is essentially a"narrative"process:patients narrate their illness stories,and doctors,through a series of humanistic narrative practices,strengthen trust and empathy between patients and doctors on an emotional and ethical level,while bridging cognitive gaps,enhancing diagnostic and treatment outcomes,and ultimately fostering a harmonious and efficient doctor-patient narrative community relationship.The realization of a doctor-patient narrative community not only optimizes the treatment process but also enhances patients'self-efficacy and doctors'professional satisfaction,which is conducive to saving medical costs,optimizing public health governance,and highlighting a harmonious social atmosphere.

Objective:To identify competency evaluation indicators for psychological hotline professionals,provi-ding scientific reference for their training and assessment.Methods:Through literature review,initial competency evalua-tion indicators were selected,followed by Delphi consultation with sixteen experts across China.The analytic hierarchy process(AHP)was used to assign weights to each indicators.Results:The response rate of expert consultation question-naire was 100％,and the expert authority coefficients for the two rounds of consultation were 0.92 and 0.90 respective-ly.After two rounds of expert consultation,a competency evaluation index system for professional counselors of psycho-logical aids hotline was constructed,including four first-level indexes,nine second-level indexes,and 34 third-level inde-xes.The weight of each index was determined using the AHP.The Kendall coefficient of concordance of all level's inde-xes in the two rounds of consultation were 0.16-0.18 and 0.16-0.25,respectively.Conclusion:The expert consensus developed in this study serves as an reference for evaluating the competency of psychological hotline professionals,sup-porting their training and assessment.

Cerebral small vessel disease is a group of age-related pathological syndromes with complex and diverse clinical symptoms.In the early stage,it is often asymptomatic or manifested as sleep or emotional disorders.Further disease development can lead to stroke or dementia,making it a crucial target for the early prevention and treatment of brain aging.Studies have shown that biological rhythm disorders are significantly associated with the onset,progression,and outcome of cardiovascular and cerebrovascular diseases.With the rapid development of modern society,the fast-paced lifestyle leads to the disorder of the body′s biological rhythm,thereby accelerating the aging process.However,few studies have investigated the correlation between cerebral small vessel disease and biological rhythm disorders in Western medicine.Sleep disorders and increased blood pressure variability related to cerebral small vessel disease may represent specific manifestations of biological rhythm disorders.The pathogenesis of cerebral small vessel disease is related to qi collaterals,and the biological rhythm disorder is mainly caused by the disorder of the growth and decline of yin and yang qi and the circulation of nutrient qi and defensive qi in the human body.Therefore,the disorder of qi rhythm may be involved in the early pathological mechanism of cerebral small vessel disease.By integrating Western medical research,this article explores the evolution of traditional Chinese medicine pathogenesis of cerebral small vessel disease associated with brain aging from the perspective of qi rhythm,aiming to provide novel diagnostic and treatment insights for the clinical treatment of cerebral small vessel disease.

OBJECTIVE To identify tortoiseshell glue and antler glue in Qichong zuogui granules,and determine the contents of 12 chemical components.METHODS Identification and content determination were performed by using liquid chromatography-tandem mass spectrometry(LC-MS/MS)method.The identification was performed on Hypersil GOLD column with a mobile phase consisted of acetonitrile-0.1％formic acid solution(gradient elution);the electrospray ion source was used to scan in the positive ion multi-reaction detection mode.The mass charge ratio(m/z)631.3→546.4,631.3→921.4 was the detection ion pair for tortoiseshell glue,and the m/z 765.4→554.0,765.4→733.0 was the detection ion pair for antler glue.The determination method for 12 chemical components was as follows:Accucore C18 column,methanol-0.1％formic acid as mobile phase(gradient elution);scanning range of positive and negative ions was m/z 100→1 000 with the electric spray ion source and single ion detection scanning mode.RESULTS Average retention times of the molecular ion peaks for characteristic peptide segments of tortoiseshell glue and antler glue were 6.28 and 6.77 min,respectively;the linear relationship of 12 chemical components was good within their respective concentration ranges,such as astragaloside Ⅳ,calycosin-7-O-β-D-glucoside,calycosin,chlorogenic acid,ferulic acid,betaine,amygdalin,rutin,hydroxysafflor yellow A,hyperoside,loganin,cyasterone(r＞0.999);RSDs for precision,stability(24 h)and reproducibility tests were all less than 5％.The average sample recovery rates ranged from 98.04％to 101.08％.The average contents of 12 components were 1.83,25.73,13.76,56.71,23.80,49.82,807.49,15.01,317.02,60.21,202.71 and 17.70 μg/g,respectively.CONCLUSIONS In this study,tortoiseshell glue and antler glue in Qixiong zuogui granules are identified,and the contents of 12 chemical components therein are determined.This provides a reference for the quality control of this granule.

Objective:To identify competency evaluation indicators for psychological hotline professionals,provi-ding scientific reference for their training and assessment.Methods:Through literature review,initial competency evalua-tion indicators were selected,followed by Delphi consultation with sixteen experts across China.The analytic hierarchy process(AHP)was used to assign weights to each indicators.Results:The response rate of expert consultation question-naire was 100％,and the expert authority coefficients for the two rounds of consultation were 0.92 and 0.90 respective-ly.After two rounds of expert consultation,a competency evaluation index system for professional counselors of psycho-logical aids hotline was constructed,including four first-level indexes,nine second-level indexes,and 34 third-level inde-xes.The weight of each index was determined using the AHP.The Kendall coefficient of concordance of all level's inde-xes in the two rounds of consultation were 0.16-0.18 and 0.16-0.25,respectively.Conclusion:The expert consensus developed in this study serves as an reference for evaluating the competency of psychological hotline professionals,sup-porting their training and assessment.

Cerebral small vessel disease is a group of age-related pathological syndromes with complex and diverse clinical symptoms.In the early stage,it is often asymptomatic or manifested as sleep or emotional disorders.Further disease development can lead to stroke or dementia,making it a crucial target for the early prevention and treatment of brain aging.Studies have shown that biological rhythm disorders are significantly associated with the onset,progression,and outcome of cardiovascular and cerebrovascular diseases.With the rapid development of modern society,the fast-paced lifestyle leads to the disorder of the body′s biological rhythm,thereby accelerating the aging process.However,few studies have investigated the correlation between cerebral small vessel disease and biological rhythm disorders in Western medicine.Sleep disorders and increased blood pressure variability related to cerebral small vessel disease may represent specific manifestations of biological rhythm disorders.The pathogenesis of cerebral small vessel disease is related to qi collaterals,and the biological rhythm disorder is mainly caused by the disorder of the growth and decline of yin and yang qi and the circulation of nutrient qi and defensive qi in the human body.Therefore,the disorder of qi rhythm may be involved in the early pathological mechanism of cerebral small vessel disease.By integrating Western medical research,this article explores the evolution of traditional Chinese medicine pathogenesis of cerebral small vessel disease associated with brain aging from the perspective of qi rhythm,aiming to provide novel diagnostic and treatment insights for the clinical treatment of cerebral small vessel disease.