Among patients with chronic sinusitis with nasal polyps, there are many refractory cases that repeatedly relapse after conventional Western medical treatment. Such patients suffer not only from nasal obstruction, nasal discharge, and posterior rhinorrhea, but also from olfactory disturbances, which have a significant impact on their daily life due to a decrease in quality of life. In this report, we describe six cases of refractory chronic sinusitis with nasal polyps and olfactory dysfunction that were effectively treated with the addition of eppikajutsuto. For patients with chronic sinusitis with nasal polyps and olfactory dysfunction who have difficulty controlling their symptoms with conventional treatment, a Kampo medicine approach may improve not only the coexisting symptoms such as olfactory dysfunction but also nasal obstruction.

Neuro-otologic disease (e.g. hearing loss, tinnitus, dizziness) are often difficult to treat because their mechanisms and causes are not fully understood and Western medical approaches are limited. This time, we report 3 cases with high-tone sensorineural hearing loss successfully treated with a Kampo formulation daisaikoto. When high-tone sensorineural hearing loss remains after treatment of acute sensorineural deafness, or for high-tone acute sensorineural deafness, a Kampo medicine approach including abdominal patterns has the potential to improve hearing as well as comorbid symptoms such as tinnitus.