1.Quality of life and influencing factors in lung cancer patients after video-assisted thoracic surgery
Yudong TANG ; Ailin LUO ; Dili ZHANG ; Xingxia LONG ; Jialu LI ; Mei YANG
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery 2023;30(04):569-575
Objective To investigate the short-term quality of life in patients after single-direction video-assisted thoracic surgery (VATS) for lung cancer, and explore the related influencing factors. Methods Patients who underwent single-direction VATS for lung cancer in the Department of Thoracic Surgery, West China Hospital, Sichuan University from July 2020 to August 2021 were continuously selected. The QLQ-C30 and QLQ-LC13 were used to evaluate the quality of life of the patients after the surgery, and the influencing factors were analyzed. Results A total of 193 patients were collected. There were 73 males aged 59.44±11.40 years, and 120 females aged 53.73±11.15 years. The QLQ-C30 score of the patients after single-direction VATS for lung cancer was 69.09±20.21 points. Univariate analysis and Pearson correlation analysis showed that age, occupation, anesthesia time, postoperative complications, postoperative antibiotic use time, postoperative hospital stay, insomnia, economic stress, hemoptysis, chest pain, dysphagia, arm or shoulder pain were associated with the quality of life (P≤0.05). The results of multiple regression analysis showed that anesthesia time, economic pressure, insomnia and chest pain had a significant impact on the overall quality of life 30 days after the surgery (P≤0.05). Conclusion The anesthesia time, economic pressure, insomnia and chest pain are independent influencing factors for the quality of life after the VATS lung cancer surgery.
2.Clinical application of preoperative MRI examination in breast-conserving surgery for ductal carcinoma in situ
Yi YANG ; Xingxia YANG ; Sili JIN ; Xu ZHANG ; Juanying ZHU ; Xiaosong CHEN
Journal of Surgery Concepts & Practice 2023;28(4):378-382
Objective: To evaluate the relationship between preoperative magnetic resonance imaging (MRI) examination and the success rate and prognosis of breast-conserving surgery in ductal carcinoma in situ (DCIS) patients. Methods: Patients with DCIS received surgery between January 2009 and January 2017 in the breast cancer medical record database of Shanghai Jiao Tong University were retrospectively analyzed. Patients who received preoperative MRI was defined as MRI group, who did not receive preoperative MRI was defined as non-MRI group. Results: A total of 210 DCIS patients were included, of which 167 cases in the MRI group and 43 cases in the non-MRI group, respectively. Initial negative resection margin rates were similar between MRI and non-MRI groups undergoing breast-conserving surgery (91.0% vs. 97.7%, P=0.142). There was also no significant difference in the success rate of breast-conserving surgery between MRI and non MRI groups (95.2% vs. 100.0%, P=0.143). In terms of prognosis, there was no significant difference in 10-year loco-regional recurrence rate (4.8% vs. 2.3%, P=0.426) and breast cancer related mortality (0.9% vs. 0.5%, P=0.668) between MRI and non-MRI groups. Conclusions: Preoperative breast MRI examination in patients with DCIS had no effect on the rate of negative resection margin, success rate of breast preservation and the prognosis of the patients.
3.Continuous improvements for the new service model in outpatient pharmacy under the environment of medical reform
Jin LU ; Yan HUO ; Dongmei ZHANG ; Rong XU ; Xingxia LI ; Li YANG ; Jianping ZHANG
Journal of Pharmaceutical Practice 2020;38(5):469-475
Objective To introduce the improvements of multi-mode outpatient pharmacy services based on the new medical reform policy. Methods The pharmacist’s roles, responsibilities, working procedures and the achievements were discussed. Results and conclusion On-site pharmacy counseling services and online WeChat pharmacy consulting services were established to include collaborative drug therapy management of pharmacists and physicians (Alzheimer's disease and anticoagulation clinic), the outpatient pharmacy services by pharmacists (chemo medication counseling). The multi-mode pharmacy services in our hospital have optimized patient's medication regime, safeguarded patient's medication therapy, improved patient's compliance and reduced medication cost. The individualized medication therapy reduced adverse reactions significantly. The multi-mode outpatient pharmacy services established by our hospital were successful and could serve as a model for other pharmacies in our country.

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