Background: The systemic immune inflammation index (SII) is a reproducible biomarker of inflammatory process. Aims: To explore the predictive value of SII for severe acute pancreatitis (SAP). Methods: A total of 406 patients with acute pancreatitis (AP) from Jan. 2013 to Dec. 2020 at Affiliated Hospital of Yangzhou University were collected, and were divided into SAP group and non SAP group. ROC curve was drawn to evaluate the value of SII, NLR, PLR, CAR for predicting SAP. Results: Compared with non‑SAP group, SII, NLR, PLR, CAR were significantly increased in SAP group (P<0.05). When the best cut‑off value was 1 705.83, AUC of SII for predicting SAP was 0.754, the sensitivity was 75.47%, and the specificity was 69.12%. AUC of SII for predicting SAP was higher than that of PLR, CAR (Z=2.647, P=0.007; Z= 2.616, P=0.008), while no significant difference was found between SII and NLR (P>0.05). And no significant difference in AUC was found between PLR and CAR (P>0.05). Conclusions: SII is a good new hematological index that can be used to predict the severity of AP, its predictive ability is similar to NLR, better than PLR and CAR.

Objective:To analyze the management and treatment of patients with psychosis in china in 2020 and compare with those in the past five years to provide a reference for making policy and service delivery.Methods:Descriptive analysis was used to analyze the system usage and registration, management, and treatment situation of the patients with psychosis, using the data obtained from 'National Information System for Psychosis′ in China, with date traced from 1st August 2011 to 31st December 2020.Results:By the end of 2020, the information system was adopted by 100% of districts/counties. 6 430 587 patients were registered, with a registered rate of 0.46% (6 430 587/1 396 537 459). In 2020, 6 116 599 patients were provided with follow-up services by primary healthcare staff, with a management rate of 95.12% (6 116 599/6 430 587). 5 724 019 patients were followed up regularly, with the regular management rate of 89.01% (5 724 019/6 430 587). Moreover, the medication-taking rate was 87.83% (5 648 162/6 430 587), and the regular medication- taking rate was 68.84% (4 426 498/6 430 587). 5 277 746 patients were stable, and the stable condition rate was 96.40% (5 277 746/5 474 881). Compared with 2019, 200 430 more patients were registered in 2020. The management rate, regular management rate, medication-taking rate, regular medication-taking rate, and stable condition rate were increased by 0.88%, 2.50%, 3.75%, 11.39%, and 1.15%, respectively. The regular medication-taking rate among patients registered in the western region was significantly lower than that in the eastern and central areas ( F=6.317, P=0.005). According to the diagnosis, the duration of the untreated period of patients registered in 2020 with schizophrenia, bipolar disorder, delusional disorder, schizoaffective disorder, psychotic disorder with epilepsy, mental retardation with psychotic symptoms were 2.69, 3.28, 1.68, 1.92, 4.70, and 9.89 years respectively, which were shorter than patients registered in 2019. Conclusion:The number of registered patients was sustainably growing. The untreated periods of newly registered patients were considerably shorter. The services and treatment situations improved in 2020. Appropriate policies should be developed to address the weaknesses of local mental health services in the western region to improve treatment rates.

Objectives:To analyze the allocation of mental health resources in Chinese mainland and the change of these resources during the 13 th Five-year Mental Health Plan period. This analysis will serve as evidence for developing future national mental health prevention and control policies. Methods:The National Mental Health Program Office created one questionnaire to survey available mental health facilities by the end of 2020. Descriptive methods were used to analyze the mental health facilities, psychiatric beds, and mental health professionals from type, sponsor, administrative level, regions, and sub-specialities.Results:By the end of 2020, 5 936 facilities were providing mental health services in Chinese mainland. 798 191 psychiatric beds (5.65 beds/10 000 persons), 50 124 psychiatrists (3.55/100 000 persons), and 139 642 registered nurses (9.89/100 000 persons) were located in these facilities. Of all these 5 936 mental health facilities, 649 (1.09%) had geriatric psychiatric wards, 312 (0.53%) had child psychiatric wards, and 1 548 (26.08%) had rehabilitation departments. 350 counties (12.31%) had no mental health facilities and 883 counties (31.05%) had no psychiatric beds in Chinese mainland, mainly in the mid-western regions. The numbers of psychiatric beds, psychiatrists, and registered nurses per unit land area in the western region were about 4 times lower than those in the middle region and 7-11 times lower than those in the eastern region.Conclusions:The mental health resources in Chinese mainland increased significantly from 2015 to 2020, but there are still the problems of uneven geographical allocation of resources and lagged sub-specialities development. While formulating the construction and development plan for mental health prevention and control system in the future, we should further develop the mental health resources at the county level, and vigorously support to establish of mental health sub-specialities for the elderly and children, as well as mental health rehabilitation, particularly in the mid-western regions.

Objective:To analyze the management and treatment of patients with psychosis in china in 2020 and compare with those in the past five years to provide a reference for making policy and service delivery.Methods:Descriptive analysis was used to analyze the system usage and registration, management, and treatment situation of the patients with psychosis, using the data obtained from 'National Information System for Psychosis′ in China, with date traced from 1st August 2011 to 31st December 2020.Results:By the end of 2020, the information system was adopted by 100% of districts/counties. 6 430 587 patients were registered, with a registered rate of 0.46% (6 430 587/1 396 537 459). In 2020, 6 116 599 patients were provided with follow-up services by primary healthcare staff, with a management rate of 95.12% (6 116 599/6 430 587). 5 724 019 patients were followed up regularly, with the regular management rate of 89.01% (5 724 019/6 430 587). Moreover, the medication-taking rate was 87.83% (5 648 162/6 430 587), and the regular medication- taking rate was 68.84% (4 426 498/6 430 587). 5 277 746 patients were stable, and the stable condition rate was 96.40% (5 277 746/5 474 881). Compared with 2019, 200 430 more patients were registered in 2020. The management rate, regular management rate, medication-taking rate, regular medication-taking rate, and stable condition rate were increased by 0.88%, 2.50%, 3.75%, 11.39%, and 1.15%, respectively. The regular medication-taking rate among patients registered in the western region was significantly lower than that in the eastern and central areas ( F=6.317, P=0.005). According to the diagnosis, the duration of the untreated period of patients registered in 2020 with schizophrenia, bipolar disorder, delusional disorder, schizoaffective disorder, psychotic disorder with epilepsy, mental retardation with psychotic symptoms were 2.69, 3.28, 1.68, 1.92, 4.70, and 9.89 years respectively, which were shorter than patients registered in 2019. Conclusion:The number of registered patients was sustainably growing. The untreated periods of newly registered patients were considerably shorter. The services and treatment situations improved in 2020. Appropriate policies should be developed to address the weaknesses of local mental health services in the western region to improve treatment rates.

Objectives:To analyze the allocation of mental health resources in Chinese mainland and the change of these resources during the 13 th Five-year Mental Health Plan period. This analysis will serve as evidence for developing future national mental health prevention and control policies. Methods:The National Mental Health Program Office created one questionnaire to survey available mental health facilities by the end of 2020. Descriptive methods were used to analyze the mental health facilities, psychiatric beds, and mental health professionals from type, sponsor, administrative level, regions, and sub-specialities.Results:By the end of 2020, 5 936 facilities were providing mental health services in Chinese mainland. 798 191 psychiatric beds (5.65 beds/10 000 persons), 50 124 psychiatrists (3.55/100 000 persons), and 139 642 registered nurses (9.89/100 000 persons) were located in these facilities. Of all these 5 936 mental health facilities, 649 (1.09%) had geriatric psychiatric wards, 312 (0.53%) had child psychiatric wards, and 1 548 (26.08%) had rehabilitation departments. 350 counties (12.31%) had no mental health facilities and 883 counties (31.05%) had no psychiatric beds in Chinese mainland, mainly in the mid-western regions. The numbers of psychiatric beds, psychiatrists, and registered nurses per unit land area in the western region were about 4 times lower than those in the middle region and 7-11 times lower than those in the eastern region.Conclusions:The mental health resources in Chinese mainland increased significantly from 2015 to 2020, but there are still the problems of uneven geographical allocation of resources and lagged sub-specialities development. While formulating the construction and development plan for mental health prevention and control system in the future, we should further develop the mental health resources at the county level, and vigorously support to establish of mental health sub-specialities for the elderly and children, as well as mental health rehabilitation, particularly in the mid-western regions.

Objective:To analyze the management and treatment situation for patients with psychosis in China in 2018, and compare with those in 2014-2017, in order to provide a reference for policy making and services delivering.Methods:Descriptive method was used to analyze the system usage and registration, management and treatment situation of the patients with psychosis, using the data obtained from “National Information System for Psychosis” in China and all provinces (municipalities, autonomous regions), date traced from 1st August 2011 to 31st December 2018.Results:By the end of 2018, the information system was adapted by 2 832 districts/counties, accounting for 99.23% of the total county-level administrative areas (2 832/2 854). 5 994 054 patients were registered, and registered rate was 0.43% (5 994 054/1 379 837 956). In 2018, 5 688 164 patients were provided with follow-up services by primary health care staffs, and the management rate was 94.90% (5 688 164/5 994 054). 4 956 545 patients were followed up regularly, with the regular management rate of 82.69% (4 956 545/5 994 054). Moreover, 4 873 322 patients were treated by taking antipsychotics, with the medication-taking rate of 81.30% (4 873 322/5 994 054), and 2 504 323 patients took medication regularly, with the regular medication-taking rate of 41.78% (2 504 323/5 994 054); 4 426 558 patients were in stable condition and the stability rate was 80.60% (4 426 558/5 492 261), which was positively correlated with the follow-up rate, regular follow-up rate, medication-taking rate and regular medication-taking rate( r=0.509, 0.695, 0.403, 0.539, all P<0.05). Comparing with 2017, there were 187 702 more registered patients in 2018 and all indicators above were higher in 2018. Duration of untreated schizophrenia, bipolar disorder, delusional disorder, schizoaffective disorder, psychotic disorder with epilepsy, mental retardation with psychotic symptoms were 3.54, 4.61, 2.73, 3.18, 5.35, 13.34 years respectively, and the duration of untreated delusional disorder and mental retardation with psychotic symptoms were shorter than those in 2017. Conclusion:Services for patients with psychosis were significantly improved in 2018. The coverage of the information system was expanded. The number of registered patients was sustainably growing. Patient management and pharmacological treatment have both improved.

Objective:To analyze the management and treatment situation for patients with psychosis in China in 2018, and compare with those in 2014-2017, in order to provide a reference for policy making and services delivering.Methods:Descriptive method was used to analyze the system usage and registration, management and treatment situation of the patients with psychosis, using the data obtained from “National Information System for Psychosis” in China and all provinces (municipalities, autonomous regions), date traced from 1st August 2011 to 31st December 2018.Results:By the end of 2018, the information system was adapted by 2 832 districts/counties, accounting for 99.23% of the total county-level administrative areas (2 832/2 854). 5 994 054 patients were registered, and registered rate was 0.43% (5 994 054/1 379 837 956). In 2018, 5 688 164 patients were provided with follow-up services by primary health care staffs, and the management rate was 94.90% (5 688 164/5 994 054). 4 956 545 patients were followed up regularly, with the regular management rate of 82.69% (4 956 545/5 994 054). Moreover, 4 873 322 patients were treated by taking antipsychotics, with the medication-taking rate of 81.30% (4 873 322/5 994 054), and 2 504 323 patients took medication regularly, with the regular medication-taking rate of 41.78% (2 504 323/5 994 054); 4 426 558 patients were in stable condition and the stability rate was 80.60% (4 426 558/5 492 261), which was positively correlated with the follow-up rate, regular follow-up rate, medication-taking rate and regular medication-taking rate( r=0.509, 0.695, 0.403, 0.539, all P<0.05). Comparing with 2017, there were 187 702 more registered patients in 2018 and all indicators above were higher in 2018. Duration of untreated schizophrenia, bipolar disorder, delusional disorder, schizoaffective disorder, psychotic disorder with epilepsy, mental retardation with psychotic symptoms were 3.54, 4.61, 2.73, 3.18, 5.35, 13.34 years respectively, and the duration of untreated delusional disorder and mental retardation with psychotic symptoms were shorter than those in 2017. Conclusion:Services for patients with psychosis were significantly improved in 2018. The coverage of the information system was expanded. The number of registered patients was sustainably growing. Patient management and pharmacological treatment have both improved.

Objective To analyze the management and treatment situation for patients with psychosis in China in 2017,and to compare with those in 2014-2016,in order to provide a reference for policy making and services delivering.Methods Descriptive method was used to analyze the system usage,registration,management and treatment situation of the patients with psychosis based upon "China National Information System for Psychosis" in the national and all provincial databases (municipalities,autonomous regions),with the date traced from 1st August 2011 to 31st December 2017.Results By the end of 2017,the information system was adapted by 2813 districts/counties,accounting for 98.56％ of the total county-level administrative areas (2 813/2 854).5 806 352 patients were registered with registration rate of 0.424％ (5 806 352/1 370 784 400).In 2017,5 380 249 patients were provided with follow-up services by primary health care staffs with the management rate of 92.66％ (5 380 249/5 806 352).4 346 103 patients were followed up regularly,with the management rate of 74.85％ (4 346 103/5 806 352).Moreover,4 035 323 patients were treated by taking antipsychotics,with the medication-taking rate of 69.50％ (4 035 323/5 806 352),and 2 012 074 patients took medication regularly,with the regular medication-taking rate of 34.65％ (2 012 074/5 806 352);3 924 101 patients were in stable condition with the stabilisation rate of 75.01％ (3 924 101/5 231 235),which was positively correlated with follow-up rate,regular follow-up rate,medication-taking rate and regular medication-taking rate(r=0.614,0.800,0.550,0.614,all P＜0.05).Comparing with 2016,there were 405 202 more patients registered in 2017 and all indicators above were higher in 2017.Durations of untreated schizophrenia,bipolar disorder,delusional disorder,schizoaffective disorder,psychotic disorder with epilepsy,mental retardation with psychotic symptoms were 3.28,4.25,2.78,2.85,4.95,14.31 years respectively,all of which were shorter than 2016.Conclusion Services for patients with psychosis were significantly improved in 2017.The coverage of the information system was expanded.The number of registered patients was sustainably growing.Patient management and medicine-taking were also improved,and the duration of untreated psychosis was shortened.

Objective To analyze the management and treatment situation for patients with psychosis in China in 2017,and to compare with those in 2014-2016,in order to provide a reference for policy making and services delivering.Methods Descriptive method was used to analyze the system usage,registration,management and treatment situation of the patients with psychosis based upon "China National Information System for Psychosis" in the national and all provincial databases (municipalities,autonomous regions),with the date traced from 1st August 2011 to 31st December 2017.Results By the end of 2017,the information system was adapted by 2813 districts/counties,accounting for 98.56％ of the total county-level administrative areas (2 813/2 854).5 806 352 patients were registered with registration rate of 0.424％ (5 806 352/1 370 784 400).In 2017,5 380 249 patients were provided with follow-up services by primary health care staffs with the management rate of 92.66％ (5 380 249/5 806 352).4 346 103 patients were followed up regularly,with the management rate of 74.85％ (4 346 103/5 806 352).Moreover,4 035 323 patients were treated by taking antipsychotics,with the medication-taking rate of 69.50％ (4 035 323/5 806 352),and 2 012 074 patients took medication regularly,with the regular medication-taking rate of 34.65％ (2 012 074/5 806 352);3 924 101 patients were in stable condition with the stabilisation rate of 75.01％ (3 924 101/5 231 235),which was positively correlated with follow-up rate,regular follow-up rate,medication-taking rate and regular medication-taking rate(r=0.614,0.800,0.550,0.614,all P＜0.05).Comparing with 2016,there were 405 202 more patients registered in 2017 and all indicators above were higher in 2017.Durations of untreated schizophrenia,bipolar disorder,delusional disorder,schizoaffective disorder,psychotic disorder with epilepsy,mental retardation with psychotic symptoms were 3.28,4.25,2.78,2.85,4.95,14.31 years respectively,all of which were shorter than 2016.Conclusion Services for patients with psychosis were significantly improved in 2017.The coverage of the information system was expanded.The number of registered patients was sustainably growing.Patient management and medicine-taking were also improved,and the duration of untreated psychosis was shortened.

Objective To analyze the management and treatment situation for patients with psychosis in China in 2016,and compare with those data in 2014 and 2015,in order to provide a reference for policy making and services delivering.Methods Descriptive method was used to analyze the information system usage and the demographic characteristics,registration,management and treatment situation of the patients with psychosis.Data was obtained from ‘National Information System for Psychosis’ and traced from 1st August 2011 to 31st December 2016.Results By the end of 2016,the information system was applied by 2 801 counties (98.14％,2 801/2 854) to register patients with psychosis in China,5401 150 patients were registered,and prevalence of registered psychosis was 3.96‰ (5 401 150/1 362 466 686).In 2016,4 873 977 patients received the follow-up services by primary health care workers,and 3 665 720 patients were followed up regularly (at least once per 3 months).The follow-up rate and regular follow-up rate were 90.24％ (4 873 977/5 401 150) and 67.87％ (3 665 720/5 401 150) respectively.Moreover,2 528 143 patients were treated by antipsychotics,and 1 594 562 patients took medication regularly (according to the prescriptions).The medication-taking rate and regular medication-taking rate were 51.87％ (2528 143/4873977) and 32.72％ (1 594562/4873977) respectively.3 265 761 patients were in stable condition during the whole year and the rate of being stable was 68.68％ (3 265 761/4 754 801),which was positively correlated with follow-up rate,regular follow-up rate,medication-taking rate and regular medication-taking rate(r=0.578,0.733,0.495,0.536,all P＜0.05).Comparing with 2015,there are extra 27 counties and 479 645 more registered patients in 2016 and all indicators above were higher in 2016.Duration of untreated schizophrenia,bipolar disorder,delusional disorder,schizoaffective disorder,psychotic disorder with epilepsy,mental retardation with psychotic symptoms was 3.89,4.40,3.06,3.01,5.64,16.56 years respectively,all of which were shorter than 2015.Conclusions Services for patients with psychosis were significantly improved in 2016.The coverage of the system was expanded and the number of registered patients increased sustainably,and at the same time the duration of untreated psychosis decreased continuously with better management and treatment.