1.Risk Assessment for Ramadan Fasting in People With Diabetes in Hospital-Based Diabetes Clinics Using the Updated 2026 IDF-DAR Risk Calculator
Raja Nurazni Raja Azwan ; Chin Voon Tong ; Lisa Mohamed Nor ; Marisa Khatijah Borhan ; Syarifah Syahirah Syed Abas ; Poh Shean Wong ; Ying Jie Tan ; Shartiyah Ismail ; Eunice Yi Chwen Lau ; Yueh Chien Kuan ; Noor Hafis Md Tob ; Shu Teng Chai ; Pei Lin Chan ; Xe Hui Lee ; Wei Wei Ng ; Jin Hui Ho ; Miza Hiryanti Zakaria ; Rabeah Md Zuki ; Wan Mohd Hafez Wan Hamzah ; Melissa Vergis ; Choon Peng Sun ; Vanusha Devaraja Pillai ; Chee Koon Low ; Shazatul Reza Mohd Redzuan ; Xin-Yi Ooi ; Siti Sanaa Wan Azman ; Deviga Lachumanan ; Saiful Shahrizal Shudim ; Zanariah Hussein
Journal of the ASEAN Federation of Endocrine Societies 2026;41(S1):42-43
Introduction:
The 2021 IDF-DAR risk calculator had been previously
evaluated in multiple studies and subsequently widely
accepted and applied in clinical practice as a practical
standardized tool for patient risk stratification. Recently
updated, the 2026 IDF-DAR Risk calculator enables a more individualized, evidence-related evaluation of patientrelated and disease-related risk factors, incorporating
modern diabetes technologies, including continuous
glucose monitoring (CGM), automated insulin delivery
(AID) systems, and advanced insulin formulations to
enhance risk stratification. This tool allows medical
professionals to tailor Ramadan practices based on overall
factors toward promoting safe fasting.
Methodology:
This prospective multicentre observational study recruited
adults with Type 1 and Type 2 diabetes attending public
hospitals nationwide. People with diabetes (PwD) intending
to perform Ramadan fasting were invited to participate
and assessed using the 2026 IDF-DAR Risk Calculator in
the 6-week pre-Ramadan period between 30th January and
19th March 2026.
Results:
A total of 458 PwD were evaluated and stratified into low
(15.7%), moderate (41%), and high risk (43.3%) categories.
Most participants had Type 2 diabetes (83.6%), with 60.3%
having a disease duration exceeding 10 years and 43%
exhibiting poor glycemic control (hemoglobin A1c >9%).
Insulin therapy was used by 76.4% of participants, including
two individuals with Type 1 diabetes using AID systems.
Most participants reported no recent hypoglycemia (76.4%),
81.0% performed glucose monitoring, and 3.3% used CGM.
Severe comorbidities were uncommon, with 1.1% having
unstable macrovascular disease and 4.4% advanced chronic
kidney disease (estimated glomerular filtration rate <30).
Notably, 72.2% received structured Ramadan education.
Conclusion
Majority of PwD attending tertiary diabetes clinics were
in the moderate- to high-risk category and intended to
fast despite medical advice against fasting in some cases.
Although most participants were on insulin therapy,
hypoglycemia was low in the pre-Ramadan period.
Integration of modern technologies, advanced insulin
therapies, and structured education may support safer
fasting practices.
Risk Assessment
;
Diabetes Mellitus
;
Hospitals
;
Fasting
2.The prevalence of advanced liver fibrosis among patients with type 2 diabetes mellitus: A single-centre experience in Penang, Malaysia
Xe Hui Lee ; Lisa Mohamed Nor ; Choon Seong Ang ; Toh Peng Yeow ; Shueh Lin Lim
Journal of the ASEAN Federation of Endocrine Societies 2023;38(1):52-61
Objectives:
This study aimed to compare the severity of COVID-19, inflammatory parameters and clinical outcomes
among patients with normal and subnormal levels of Vitamin D.
Methodology:
This is a retrospective cohort study of 135 patients admitted in a tertiary hospital for COVID-19. Patients
were grouped according to their Vitamin D level. Primary outcome measure was the composite of all-cause mortality and
morbidity. Other outcome measures determined were the comparison among the groups on the severity of COVID-19
infection, changes in inflammatory parameters, length of hospital stay and duration of respiratory support.
Results:
There was a significant trend of higher ICU admission, mortality (p-value= 0.006) and poor clinical outcome
(p-value=0.009) among the Vitamin D deficient group. No significant difference was found for most of the inflammatory
parameters, duration of hospital stay and respiratory support. Overall, patients with deficient, but not insufficient Vitamin
D level had 6 times higher odds of composite poor outcome than those with normal Vitamin D (crude OR=5.18, p-value=
0.003; adjusted OR =6.3, p-value=0.043).
Conclusion
The inverse relationship between Vitamin D level and poor composite outcome observed in our study
suggests that low Vitamin D may be a risk factor for poor prognosis among patients admitted for COVID-19.
type 2 diabetes mellitus
;
Non-alcoholic Fatty Liver disease


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