1.Investigation and analysis of nutrition knowledge and current situation among employees in a tertiary hospital in Guangzhou
Ting YANG ; Shengluo LIN ; Zesheng LIN ; Weizhu CHEN
Modern Hospital 2024;24(10):1606-1610
Objective Nutrition plays an indispensable role in disease prevention,recovery,and medical improvement.The ability of medical staff to master correct nutrition knowledge plays an important role in nutritional support and education for disease recovery.This survey aims to invest the nutritional knowledge,attitudes,and dietary behaviors of medical staff in a tertia-ry hospital in Guangzhou.Methods Questionnaire surveys is conducted as a sampling survey for nutritional knowledge and be-havior in medical staff,including the mastery of nutrition knowledge,nutritional behavior habits,and others.Results Accuracy Rate of nutrition knowledge was only 49.72%in medical staff while 68%present with high enthusiasm for learning nutrition knowledge.Forty-four percent believe that the current public opinion lacks sufficient promotion of nutrition,resulting in a lack of nutrition knowledge and attention to the actual dietary situation.Conclusion Improvement of nutrition knowledge training,dieta-ry structure and lifestyle of medical staff,could promote both their physical health and their patients'health status.
2.Effectiveness and safety of the home-made umbrella-shaped Octoparms inferior vena cava filter in the prevention of pulmonary embolism
Boxiang ZHAO ; Jianlong LIU ; Gaojun TENG ; Caifang NI ; Hao XU ; Zhen LI ; Shuiting ZHAI ; Yanrong ZHANG ; Hua XIANG ; Weizhu YANG ; Jianping GU
Chinese Journal of Radiology 2022;56(5):556-562
Objective:To evaluate the effectiveness and safety of the home-made umbrella-shaped Octoparms inferior vena cava filter in the prevention of pulmonary embolism.Methods:A multicenter, randomized, positive parallel controlled, non-inferiority clinical trial was conducted in ten hospitals in China from October 2017 to March 2019. A total of 188 subjects were enrolled according to the same inclusion and exclusion criteria in different institutes. The 188 subjects were randomly divided into the trial group or the control group according to 1∶1 by the central randomization system, with 94 cases in each group. Octoparms inferior vena cava filter was used in the trial group, and the Celect inferior vena cava filter in the control group. The primary effective index was clinical success rate,including the clinical success rate of filter placement and filter retrieval. The secondary index included the rate of manual success of the delivery sheath system,incidence of pulmonary embolism(within 6 months), incidence of filter fracture,migration (>20 mm),tilt(>15°) on insertion/retrieval,and the situation of inferior vena cava flow(within 6 months). Safety evaluation included the incidence of filter related complications and device-related adverse events immediately after surgery and during follow-up.Results:The success rate of implantation was 100% in 188 subjects. Filter retrieval was performed in 87 cases (92.55%) in the trial group and 91 cases (96.81%) in the control group. The clinical success rate of the trial group was 97.87%(92/94) and that of the control group 98.94%(93/94). There was no significant difference between the two groups (χ 2=0.77, P=0.380). The success rate of delivery sheath system was 96.81%(91/94) and 98.94%(93/94) in the trail group and the control group,respectively. There was no significant difference between the two groups( P=0.621). There was 1 case (1.22%) of new asymptomatic pulmonary embolism in the trial group after filter placement and 2 cases (2.44%) in the control group. There was no significant difference between the two groups ( P>0.05). No filter fracture or migration (>20 mm) occurred in either group. The tilting of filter (>15°) was found in 1 case (1.06%) in the test group and 1 case (1.06%) in the control group when the filter was placed. The tilting of filter (>15°) was found in 0 case in the test group and 2 cases (2.44%) in the control group when the filter was retrieved. There was no significant difference between the two groups ( P>0.05). Inferior vena cava thrombosis before filter retrieval was found in 5 cases (5.75%) in trial group and 3 cases (3.30%) in control group. There was no significant difference between the two groups ( P=0.489). There were no immediate serious complications during filter placement/removal in either group. No filter obstruction,migration,deformation,penetration and occlusion of inferior vena cava. The incidence of device-related adverse events was low in both group. There was no significant difference between the two groups ( P>0.05). Conclusion:The home-made umbrella-shaped Octoparms inferior vena cava filter is effective and safe in preventing pulmonary embolism, and is not worse than Celect filter.
3.Rationale and Study Design for Evaluating the Efficacy and Safety of Intracardiac Echocardiography-Guided Minimal-Fluoroscopy Ablation in Patients with Paroxysmal Atrial Fibrillation: A Non-Inferior, Multi-Center, Prospective Randomized Controlled Trial (PAF-ICE Trial)
Jiang RUHONG ; Liu XINGPENG ; Zhang JIDONG ; Chen YU ; Wang RUI ; Wu MENGZUO ; Long DEYONG ; Li JIA ; Wang HAIXIONG ; Fan JIE ; Ju WEIZHU ; Ge WEILI ; Liu XU ; Deng HAI ; Wang WEIJIAN ; Yang PINGZHEN ; Li DING ; Huang XIAOBO ; Liu XIONGTAO ; Tao HAILONG ; Paul C. ZEI ; Tung RODERICK ; Wang XUNZHANG ; Jiang CHENYANG
Cardiology Discovery 2021;01(4):228-232
The feasibility and safety of intracardiac echocardiography (ICE)-guided catheter ablation for atrial fibrillation (AF) using a minimal/zero-fluoroscopy approach have recently been reported. This approach helps to reduce ionizing radiation exposure and orthopedic complications resulting from using lead aprons. The objectives of this planned prospective, multicenter randomized controlled trial (RCT) (paroxysmal AF (PAF)-ICE trial; ChiCTR2000033624) are to evaluate the efficacy and safety of ICE-guided minimal-fluoroscopy ablation in patients with PAF and the impact on occupational hazards among lab staff.Patients will be randomized in a 1:1 ratio to 2 groups: minimal fluoroscopy group ( n = 216) and traditional approach group ( n = 216). In the minimal fluoroscopy group, an ICE catheter will be used for geometry/anatomic construction, transseptal puncture, catheter tracking, and effusion monitoring. Pulmonary vein isolation (PVI) will be performed using an open-irrigated radiofrequency SmartTouch Surround Flow or SmartTouch catheter (Biosense Webster, Diamond Bar, California, USA), and confirmed by a multipolar Lasso or PentaRay catheter (Biosense Webster). In the traditional approach group, an ICE catheter will not be used. Transseptal puncture will be performed under fluoroscopic guidance, with all geometries constructed by mapping the catheters. The primary efficacy endpoint is freedom from AF recurrence (without antiarrhythmic medications) at 12 months after ablation. Other endpoints include duration of lead apron use, measures of intra-procedural efficiency, and peri-procedural complications. This RCT will evaluate the efficacy and safety of ICE-guided minimal-fluoroscopy ablation in patients with PAF, also evaluate the benefits to lab staff (regarding reducing occupational hazards) related to this "minimal/zero-fluoroscopy" and "leadless" mode.
4.Rationale and Study Design for Evaluating the Efficacy and Safety of Intracardiac Echocardiography-Guided Minimal-Fluoroscopy Ablation in Patients with Paroxysmal Atrial Fibrillation: A Non-Inferior, Multi-Center, Prospective Randomized Controlled Trial (PAF-ICE Trial)
Jiang RUHONG ; Liu XINGPENG ; Zhang JIDONG ; Chen YU ; Wang RUI ; Wu MENGZUO ; Long DEYONG ; Li JIA ; Wang HAIXIONG ; Fan JIE ; Ju WEIZHU ; Ge WEILI ; Liu XU ; Deng HAI ; Wang WEIJIAN ; Yang PINGZHEN ; Li DING ; Huang XIAOBO ; Liu XIONGTAO ; Tao HAILONG ; Paul C. ZEI ; Tung RODERICK ; Wang XUNZHANG ; Jiang CHENYANG
Cardiology Discovery 2021;01(4):228-232
The feasibility and safety of intracardiac echocardiography (ICE)-guided catheter ablation for atrial fibrillation (AF) using a minimal/zero-fluoroscopy approach have recently been reported. This approach helps to reduce ionizing radiation exposure and orthopedic complications resulting from using lead aprons. The objectives of this planned prospective, multicenter randomized controlled trial (RCT) (paroxysmal AF (PAF)-ICE trial; ChiCTR2000033624) are to evaluate the efficacy and safety of ICE-guided minimal-fluoroscopy ablation in patients with PAF and the impact on occupational hazards among lab staff.Patients will be randomized in a 1:1 ratio to 2 groups: minimal fluoroscopy group ( n = 216) and traditional approach group ( n = 216). In the minimal fluoroscopy group, an ICE catheter will be used for geometry/anatomic construction, transseptal puncture, catheter tracking, and effusion monitoring. Pulmonary vein isolation (PVI) will be performed using an open-irrigated radiofrequency SmartTouch Surround Flow or SmartTouch catheter (Biosense Webster, Diamond Bar, California, USA), and confirmed by a multipolar Lasso or PentaRay catheter (Biosense Webster). In the traditional approach group, an ICE catheter will not be used. Transseptal puncture will be performed under fluoroscopic guidance, with all geometries constructed by mapping the catheters. The primary efficacy endpoint is freedom from AF recurrence (without antiarrhythmic medications) at 12 months after ablation. Other endpoints include duration of lead apron use, measures of intra-procedural efficiency, and peri-procedural complications. This RCT will evaluate the efficacy and safety of ICE-guided minimal-fluoroscopy ablation in patients with PAF, also evaluate the benefits to lab staff (regarding reducing occupational hazards) related to this "minimal/zero-fluoroscopy" and "leadless" mode.
5.Transjugular intrahepatic portosystemic shunt by using covered stents of different diameters for the treatment of esophagogastric varices rupture with bleeding
Hui ZHENG ; Weizhu YANG ; Ning HUANG ; Jingyao HUANG ; Qubin ZHENG ; Na JIANG ; Zhengzhong WU ; Quan SHEN ; Kun KE
Journal of Interventional Radiology 2018;27(2):167-171
Objective To assess the efficacy and safety of different diameter covered stents used in transjugular intrahepatic portosystemic shunt (TIPS) for esophagogastric varices with bleeding (EGVB). Methods The clinical data of 68 patients with portal hypertension due to cirrhosis, who received TIPS for EGVB during the period from Desember 2010 to February 2015, were retrospectively analyzed. Among the 68 patients, covered stent with diameter of 7mm was used in 30 (small stent group) and covered stent with diameter of 8mm was employed in 38 (big stent group). Using Kaplan-Meier method, the cumulative digestive tract no-rebleeding rate, the patency rate of shunt and the survival rate of both groups were analyzed. Logrank test was used to make comparison between the two groups, and chi-square test was conducted to compare the incidence of hepatic encephalopathy between the two groups. Results The operative success rate was 100% in 68 patients. The patients were followed up for 0.1-52.3 months, with a mean of (19.4±16.0) months. The 3-, 6-and 12-month cumulative digestive tract no-rebleeding rates were 86.54%, 79.30% and 74.90% respectively in the small stent group, which were 91.87%, 85.93% and 81.63% respectively in the big stent group, but the differences between the two groups were not statistically significantly (X2=0.05, P=0.83). The 3-, 6-and 12-month cumulative patency rates of shunt in the small stent group were 95.00%, 80.19% and 70.17% respectively, which in the big stent group were 96.15%, 91.97% and 81.07% respectively, and no statistically significant differences existed between the two groups (X2=0.40, P=0.53). The 3-, 12-, 24-and 48-month cumulative survival rates in the small stent group were 93.33%, 86.67%, 75.11% and64.38% respectively, while those in the big stent group were 97.37%, 94.23%, 88.68% and 76.02% respectively, and the differences between the two groups were not statistically significantly (X2=2.21, P=0.14). Postoperative hepatic encephalopathy occurred in 15 patients (15/68, 22.06%), the incidences of hepatic encephalopathy in the small stent group and in the big stent group were 20.00% (6/30) and 23.68% (9/38) respectively, the difference between the two groups was not statistically significantly (X2=0.13, P=0.72). Conclusion Compared with the use of 7mm covered stent, the use of 8mm covered stent in TIPS neither can improve the curative effect nor can reduce the incidence of hepatic encephalopathy.
6.Transjugular intrahepatic portasystemic shunt with Viatorr covered stent
Hui ZHENG ; Quan SHEN ; Weizhu YANG ; Ning HUANG ; Jingyao HUANG ; Qubin ZHENG ; Na JIANG ; Zhengzhong WU ; Kun KE
Chinese Journal of Interventional Imaging and Therapy 2017;14(10):597-601
Objective To assess the efficacy and safety of transjugular intrahepatic portasystemic shunt (TIPS) with Viatorr covered stent in patients with portal hypertension-related complications.Methods Clinical data of 8 patients with por-tal hypertension-related complications were analyzed retrospectively.All the cases received TIPS with Viatorr covered stent.After the operation,the followed up was used to evaluate the therapeutic effect of TIPS by enhanced CT scan.Results All the operations of TIPS were technically successful.And all the cases were treated with Viatorr covered stents with diameter of 8 mm and covered segment length of 50-80 mm.For 1 case with cavernous transformation of portal vein,a 8 mm×40 mm E-Luminexx bare stent was implanted in the portal vein side.For 1 case with hepatic vein stenosis,a 8 mm× 40 mm Fluency covered stent was implanted in the hepatic vein side.After the operation,the portal pressure reduced from (33.08 [29.32,40.22])mmHg (preoperative) to (23.31 [21.43,26.51])mmHg (postoperative) with statistical difference (Z=-2.52,P=0.012).The patients were followed up for 1.1-7.7 months,and all the patients were alive without complications of portal hypertension.There were 2 cases with mild hepatic encephalopathy after operation.During the reexamination time of 1-7.7 months,all TIPS shunts remained patency.Conclusion TIPS with Viatorr stent is a safe and effective treatment for patients with portal hypertension-related complications.
7.Discussion on application effects of clinical nursing pathway on recovery of upper-extremity functions during different stages after surgery of breast tumor
Wei ZHENG ; Weizhu WU ; Feihong ZHU ; Tong YANG ; Zhenfang KONG
China Modern Doctor 2015;(14):140-143
Objective To explore the application effects of clinical nursing pathway on recovery of upper-extremity functions during different stages after surgery of breast tumor. Methods A total of 120 patients who received the surgery of breast tumor in our hospital from January 2012 to December 2013 were selected as research subjects. They were randomly assigned to a research group and a regular group according to the method of random number table, with 60 in each. The regular group was given clinical regular nursing for the recovery of upper-extremity functions after the surgery, and the research group was given clinical nursing pathway for the recovery of upper-extremity functions after the surgery. Nursing effects were observed between the two groups. Results Arms bending forward and arms bending inward as well as abduction and rotation in the research group were significantly better than those in the regular group, and the differences were statistically significant (P<0.05). Satisfaction rate on clinical nursing in the research group was 93.3%, higher than that of 75.0%in the regular group(P<0.05). Life quality score in the research group was(56.1±5.9), significantly higher than that of(43.8±6.3)in the regular group, and the difference was statistically significant(P<0.05). Conclusion Clinical nursing pathway is feasible clinically for the recovery of upper-extremity functions during different stages after the surgery of breast tumor. It promotes the recovery of upper-extremity functions, as well as en-hances satisfaction rate on clinical nursing and life quality, which is worthy of clinical application.
8.Percutaneous implantation of 125I seed- strip combined with biliary stent for the treatment of malignant biliary obstruction:analysis of 38 cases
Jingyao HUANG ; Weizhu YANG ; Na JIANG ; Qubing ZHENG ; Ning HUANG ; Hang XIE
Journal of Interventional Radiology 2014;(7):633-636
Objective To investigate the clinical efficacy of percutaneous transhepatic insertion of biliary stent (PTIBS) combined with radioactive seed implantation in treating malignant biliary obstruction. Methods A total of 38 patients with malignant biliary obstruction were enrolled in this study. Radioactive 125I seed was used, and each 125I seed was 4.5 mm in length and 0.8 mm in diameter. The 125I seeds were placed in a catheter to prepare the 125I seed- strip. PTCD was carried out first, then percutaneous catheterization was performed and a guide- wire was inserted through the catheter until it passed the obstructed biliary segment. The obstructed segment was dilated by a balloon - catheter, which was followed by PTIBS. An 8 - 10 F drainage - catheter was placed into the biliary duct through the stent. Finally, guided by fluoroscopy the catheter with the 125I seed- strip was inserted via the drainage- catheter to the area that was planned to be radiated. The external drainage- catheter was wrapped and fixed to the skin, or was imbedded under the skin. Results Of the 38 patients with malignant biliary obstruction, successful PTIBS combined with radioactive seed implantation was accomplished in 36 patients. After the treatment, the serum bilirubin level fell to normal or near normal range in all patients (P < 0.05). No obvious side effects were observed. Conclusion For the treatment of malignant biliary obstruction, percutaneous transhepatic insertion of biliary stent combined with radioactive 125I seed - strip implantation is a safe and effective method.
9.The curriculum reform of the experiment aiming to improve the practical skill level of the undergraduates majoring in medical imaging
Li LIN ; Weizhu YANG ; Jian LI
Chinese Journal of Medical Education Research 2014;(7):696-698,699
With the rapid development of medical imaging equipment, the higher requirement for the practice skills of the medical imaging professionals has been put forward. The traditional “CT and MR diagnostics” experimental teaching has some disadvantages, such as poor quality of images, imbalance of teaching resources, students' lack of practical skills training, no reflection of the practi-cal skills in the course examination and so on. They are not conducive to the cultivation of talents. Aimed to improve the experimental teaching quality of the course and students' practical skills, the reformative teaching method and means have been carried out, such as improving the laboratory facil-ities , composing experimental guidance , encouraging students to learn actively , strengthening the examination of practical skills, cultivating teachers in many different ways and so on. Through the survey, 92.9% of the students expressed satisfaction with the experimental course teaching reform. These measures will also be used in the teaching of all the sub courses of medical imaging diagnostics to promote the medical imaging professional training.
10.Cryoplasty for the treatment of iliac artery stenosis in canine model
Zhengzhong WU ; Weizhu YANG ; Na JIANG ; Qubin ZHENG ; Jingyao HUANG ; Ning HUANG ; Quan SHEN
Chinese Journal of Radiology 2013;(4):364-367
Objective To evaluate the treatment effect of balloon angioplasty and cryoplasty on iliac artery stenosis in canine model.Methods Canine models of iliac artery stenosis were established with surgical ligation and transfixion.Models were randomly divided into two groups:iliac artery stenosis treated by cryoplasty (n =8) and by balloon angioplasty (n =8).The degree of iliac artery stenosis of two model groups was assessed by digital subtraction angiography (DSA) immediately and two weeks after the angioplasties.Then all the dogs were executed for pathological observation of the target vessels.Results Sixteen canine models of iliac artery stenosis were established by surgical ligation and transfixion method with 100% success rate.DSA showed there was (45 ± 12)% of residual artery stenosis in the cryoplasty group immediately after surgery,while it was (39-12)% in the balloon angioplasty group,and there was no significant difference between them(t =3.183,P > 0.05).The artery stenosis of cryoplasty group was (48 ± 17) % after two weeks and not significantly different from that after surgery immediately (t =-1.271,P > 0.05).The artery stenosis of balloon angioplasty group was (67 ± 13)% after two weeks,and it was significantly higher compared with at after surgery immediately (t =-6.666,P < 0.01).The degree of vascular stenosis in balloon angioplasty group was severer than that in cryoplasty group two weeks after angiography(P =0.041).The pathological examination showed artery intimal hyperplasia in cryoplasty group was milder than that in balloon angioplasty group and neointimal content of collagen in cryoplasty group was less than that in balloon angioplasty group.Conclusions The animal models of iliac artery stenosis were established successfully with surgical ligation and transfixion by damaging the intima and media of arterial wall.Compared with balloon angioplasty,the cryoplasty was able to inhibit proliferation of intimal and reduce collagen synthesis to prevent the iliac artery restenosis.

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