1.Revision of quality indicators for cervical cancer and trend analysis of existing indicators in Japan
Tamaki KAKUWA ; Ryoko RIKITAKE ; Satoru NAGASE ; Mikio MIKAMI ; Tsukasa BABA ; Masanori KANEUCHI ; Hideki TOKUNAGA ; Manabu SEINO ; Toshinari MURAMATSU ; Wataru YAMAGAMI ; Kazuhiro TAKEHARA ; Hitoshi NIIKURA ; Yasuyuki HIRASHIMA ; Kiyoshi YOSHINO ; Yuichi ICHINOSE ; Akira KAWATA ; Takahiro HIGASHI
Journal of Gynecologic Oncology 2025;36(5):e78-
Objective:
Cervical cancer rates in Japan (16.0/100,000) exceed the global average rate (11.3/100,000, according to the High/Very-High Human Development Index in 2020). This necessitates the evaluation of care quality and the quality indicators (QIs) for cervical cancer that were developed in 2013 to serve this purpose. This study updated these indicators using current evidence and consensus while longitudinally examining trends in practice patterns.
Methods:
The revision involved reviewing existing QIs and patterns of care indicators and incorporating new indicators using the modified Delphi method. Adherence to these indicators was assessed using a linked hospital-based cancer registry-based diagnostic procedure combination database covering approximately 70% of patients with cancer in Japan. The longitudinal trends of the existing indicators were evaluated using the linear probability model.
Results:
Seven new indicators were added to the existing twelve. Two of the new indicators mainly focused on early-stage surgical intervention, while one focused on advanced-stage bevacizumab combination therapy, with adherence rates of 81.7%, 0.8%, and 45.9%.Longitudinal analyses revealed significant improvements with the use of cisplatin in concurrent chemoradiotherapy for advanced-stage cervical cancer (+1%/year), oral anticancer agents as maintenance therapy after primary treatment for early-stage cervical cancer (−0.8%/ year), and hysterectomy for adenocarcinoma in situ in patients above 44 years old (−2%/year).
Conclusion
The QIs for cervical cancer in Japan have been revised based on 2022 evidence.The existing and new indicators should be continually evaluated to correspond to the latest knowledge. This will facilitate the standardization and promotion of bottom-up improvements in cervical cancer care.
2.Contribution of Visceral Fat Accumulation to Metabolic and Vascular Complications in Obesity.
Tsuneo OHNO ; Keisuke ITOH ; Wataru MURAMATSU ; Tomomitsu TANI ; Fuminori OKUMURA ; Yoshiaki YAMADA ; Kunio KASUGAI ; Toshiaki SHIGEYASU ; Takashi MONOE ; Kouji NAGAHARA
Journal of the Japanese Association of Rural Medicine 1995;44(4):592-596
In patients with the visceral fat type obesity, there is a high incidence of glucose and lipid metabolic abnormalities and hypertension. We obtained the following results from a study of the relationship between the degree of visceral fat obesity and metabolic and vascular complications in 98 obese patients with various complications.
1. Viceral fat obesity (V/S ratio ≥ 0.4) was found in 74% of the subjects. The incidence was higher in males than females. The highest incidence was observed in both men and women in thier 40s, and there was no increase with age.
2. The V/S ratio was high in patients with hyperlipidemia, diabetes, and fatty liver in that order. In the V/S ≥ 0.4 group, there was a higher incidence of hyperlipidemia and ischemic heart disease than in the V/S<0.4 group.
3. The V/S ratio was higher in the patients with two or more metabolic and vascular complications than in those with only one complication.
4. A questionnaire survey showed that there were many individuals who did almost no exercise and had a long history of obesity in the V/S ≥ 0.4 group.
5. The V/S ≥ 0.4 group had high triglyceride levels. There was a positive correlation between the V/ S ratio or V value and the trigyceride level, but no correlation between S value and triglyceride level.


Result Analysis
Print
Save
E-mail