1.Drivers for decision change in getting vaccinated against COVID-19: A retrospective cross-sectional study
Rosemary R. Seva ; Lourdes Marie S. Tejero ; Bettina Joyce P. Ilagan
Acta Medica Philippina 2026;60(3):60-69
Background:
A certain percentage of the vaccinated population initially did not want to get vaccinated but changed
their minds (from 30% to 70%). By October 2022, World Bank reported that the Philippines had 77.8% COVID-19 vaccination rate. Knowing the factors that changed their decision can help improve the vaccination rate.
Objective:
This survey aimed to identify the factors that influence positive change in vaccination decisions.
Methods:
This survey was conducted in the Philippines among Filipinos aged 18-80 years old between March to April 2022. The dependent variable in the study was decision change, a binary variable coded as 1 for a vaccinated person who changed their decision from no to yes and 0 for an unvaccinated person who did not change their decision from yes to no.
Results:
Age (adjusted odds ratio [aOR] = 0.92, 95% CI = 0.89-0.96) and having a college degree (aOR=11.707,
95% CI=3.23-42.41) are related to changing decisions. Young and college degree holders are likely to change their decisions positively about getting vaccinated. Employer requirement also influences decision change because it affects a person's livelihood. High scores on vaccine confidence (aOR = 1.181, 95% CI = 1.12-1.25) and awareness (aOR = 1.318, 95% CI = 1.08-1.61) are associated with decision change.
Conclusion
Being young, educated, employed with a requirement to vaccinate, and having high vaccine awareness
and confidence are strongly associated with a positive change in the decision to get vaccinated.
Vaccines
;
Vaccination
;
Philippines
;
Awareness
;
Covid-19
2.COVID-19 vaccine literacy, confidence, and vaccination coverage in two Geographically Isolated and Disadvantaged Areas (GIDAs) in Floridablanca, Pampanga: A descriptive cross-sectional study
Dennise Grace C. Lazam ; Juean Joloue D. Lama ; Azizzah M. Lao ; Mark Brandon G. Lao ; Jerenlyn A. Laxamana ; Kayla Gabrielle C. Lecciones ; Ma. Hannah Sofia R. Magtibay ; Juan Miguel M. Mañ ; ago ; Angelica Mae G. Manalo ; Nicole Ira L. Manere ; Charles Kevin L. Rivera, MD ; Maria Peñ ; afrancia L. Adversario, MD, MSPH ; Maria Milagros U. Magat, MD, MEM
Health Sciences Journal 2026;15(1):23-35
Introduction:
Effective vaccination campaigns have been instrumental in reducing COVID-19 transmission and severe disease outcomes. Despite efforts to improve vaccine accessibility, vaccine literacy and confidence remain important determinants of vaccine uptake. Rural and geographically isolated communities often experience barriers to healthcare access that may affect vaccination coverage. This study aimed to assess COVID-19 vaccination coverage, vaccine literacy, and vaccine confidence among residents of selected Geographically Isolated and Disadvantaged Areas (GIDAs) in Floridablanca, Pampanga.
Methods:
A descriptive cross-sectional study was conducted among 211 residents of Barangays San Ramon and Nabuclod. Data were collected through face-to-face interviews using a translated and pretested questionnaire on vaccine literacy and vaccine confidence. Vaccination records obtained from the Rural Health Unit were reviewed to determine COVID-19 vaccination coverage. Descriptive statistics, including
frequencies and percentages, were used to summarize the data.
Results:
The majority of respondents demonstrated an average level of vaccine literacy (75.8%), while 17.5% exhibited high vaccine literacy. Most respondents also demonstrated positive to very positive vaccine confidence (71.6%). Among the eligible population, 80.5% had completed the primary COVID-19 vaccination series, whereas 19.5% remained unvaccinated. Among those who completed the primary series, only 24.2% had received at least one booster dose.
Conclusion
Residents of the selected GIDAs generally demonstrated average vaccine literacy, positive vaccine confidence, and relatively high primary COVID-19 vaccination coverage. However, low booster uptake and the persistence of unvaccinated individuals highlight the need for sustained health education, improved healthcare accessibility, and targeted community-based interventions. These findings underscore the importance of strengthening vaccine literacy and confidence to support future immunization programs in geographically isolated communities.
COVID-19
;
Rural Health
;
Vaccination coverage
3.Expert opinions on influenza vaccination for patients with common cardiovascular diseases.
Chinese Journal of Internal Medicine 2025;64(1):11-22
The influenza virus is classified as a single-stranded negative-sense RNA virus in Orthomyxoviridae family, with epidemiological properties distinct from common cold. Previous studies have found that influenza infection can cause cardiac damage through various pathways, and patients with cardiovascular diseases are at relatively higher risk of adverse disease outcomes. Influenza vaccination has been proven to provide protective effect on patients with cardiovascular diseases. Currently, there is insufficient emphasis placed by cardiologists and cardiovascular disease patients on the prevention of influenza infection, leading to a low influenza vaccination rate in China. Therefore, based on the current clinical research progress and relevant guidelines, combined with the safety, feasibility and health economic benefits of influenza vaccinating in patients with cardiovascular diseases, as well as clinical experience from experts, this article proposes expert opinions on influenza vaccination in common cardiovascular diseases aiming to raise awareness of influenza prevention and benefiting patients.
Humans
;
Cardiovascular Diseases/prevention & control*
;
Influenza Vaccines/administration & dosage*
;
Influenza, Human/prevention & control*
;
Vaccination
;
Expert Testimony
4.National Trends in Influenza Vaccination Rates in South Korea Before and During the COVID-19 Pandemic, 2011-2022.
Kyeongeun KIM ; Kyeongmin LEE ; Yejun SON ; Seoyoung PARK ; Raphael UDEH ; Jiseung KANG ; Hayeon LEE ; Soeun KIM ; Jaeyu PARK ; Hyeon Jin KIM ; Damiano PIZZOL ; Lee SMITH ; Jiyoung HWANG ; Dong Keon YON
Biomedical and Environmental Sciences 2025;38(9):1044-1057
OBJECTIVE:
Despite the global decrease in influenza infections during the coronavirus disease 2019 (COVID-19) pandemic, seasonal influenza remains a significant health issue. South Korea, known for its robust pandemic response and high influenza vaccination rates, offers a unique context for examining changes in vaccination trends during the pandemic. Using nationally representative data, we aimed to understand the impact of the pandemic on influenza vaccination behavior over a 12-year period and to identify vulnerable groups.
METHODS:
We analyzed influenza vaccination rates in South Korea between 2011-2022, focusing on pandemic-related impacts. The data of 2,426,139 adults (≥ 19 years) from the Korea Community Health Survey were used to assess demographic and sociological factors influencing vaccination behaviors.
RESULTS:
We observed an increase in influenza vaccination rates during the pre-COVID-19 period from 2011-2013 (weighted prevalence: 46.68% [95% confidence interval ( CI): 46.55-46.82]) to 2017-2019 (weighted prevalence: 52.50% [95% CI: 52.38-52.63]). However, a significant decline was observed in 2022, the late-COVID-19 pandemic period (weighted prevalence: 55.78% [95% CI: 55.56-56.01]), compared with the mid-pandemic period in 2021 (weighted prevalence: 59.12% [95% CI: 58.91-59.32]), particularly among populations traditionally prioritized for influenza vaccination, including older adults (≥ 65 years) and patients with chronic diseases and low educational and income levels.
CONCLUSION
The influenza vaccination rate in South Korea was significantly affected by the COVID-19 pandemic, showing a notable decrease among vulnerable demographic groups. This suggests the need for targeted public health strategies to address vaccine hesitancy and improve vaccination rates, particularly among high-risk populations.
Humans
;
Republic of Korea/epidemiology*
;
COVID-19/epidemiology*
;
Adult
;
Middle Aged
;
Influenza Vaccines/administration & dosage*
;
Male
;
Female
;
Influenza, Human/epidemiology*
;
Aged
;
Vaccination/statistics & numerical data*
;
Young Adult
;
Pandemics
;
SARS-CoV-2
5.Effectiveness of an educational intervention in increasing knowledge and willingness to vaccinate on human papillomavirus among women in barangay West Fairview, Quezon City
Lesly Mae D. Mara ; Camilla Thea S. Paraino ; Jebb Patrick Molina Delos Santos
Philippine Journal of Health Research and Development 2025;29(4):8-16
BACKGROUND
Cervical cancer, caused by human papillomavirus (HPV), is the second most common cancer among Filipino women. Despite vaccine availability, the Philippines has a low 60% immunization rate, driven by hesitancy and poor public awareness.
AIMS AND OBJECTIVESThis study assessed how 100 women (ages 18–45) in Quezon City understood HPV and their willingness to vaccinate.
MATERIALS AND METHODSResearchers used a pre–post interventional study and purposive sampling and Cochran’s formula for size calculation. Participants completed a pretest, a Department of Health/World Health Organization/Centers for Disease Control and Prevention-based digital educational intervention, a posttest, and a satisfaction survey. Data were gathered confidentially under informed consent.
RESULTSResults showed significant improvement in knowledge and willingness to vaccinate (P < 0.001), with almost all respondents expressing willingness. The intervention received high satisfaction ratings, proving the digital tool was effective and well-received.
CONCLUSION AND RECOMMENDATIONIn conclusion, this study demonstrated that a structured digital educational tool effectively bridges knowledge gaps and addresses vaccine hesitancy in a community setting. Findings emphasize the importance of targeted, community-level initiatives to reduce cervical cancer risk. Future research should include teens and males and use a larger randomized sample for definitive evidence.
Human ; Female ; Adolescent: 13-18 Yrs Old ; Young Adult: 19-24 Yrs Old ; Adult: 25-44 Yrs Old ; Middle Aged: 45-64 Yrs Old ; Uterine Cervical Neoplasms ; Human Papillomavirus Viruses ; Vaccination ; Women
6.Knowledge, attitudes, and practices of senior high school students in Manila city on Human Papillomavirus (HPV) infection and vaccination: a descriptive cross-sectional study.
Japheth Mye S. DINGLASAN ; Joyce Belle S. DINGLASAN ; Angelica D. ; Kirsten Danielle R. DOCTORA ; Tricia Gale A. DOMAI ; Shane Clarence C. DOMINGO ; Andrei P. DUHAYLUNGSOD ; Paula Mae A. DYCHITAN ; Alexandrina E. EBOÑA ; Charina C. EBREO ; Jan Rey S. ESCANO ; Jasmine Lianne B. ESGUERRA ; Marjorie M. ESPEDIDO ; Arienne Therese P. EVANGELISTA ; Kimberly F. EVIZA ; Jose Ronilo G. JUANGCO ; Maribel Emma Co- HIDALGO
Health Sciences Journal 2025;14(2):106-114
OBJECTIVES
Human papillomavirus (HPV) is a prevalent sexually transmitted infection linked to cervical and anal cancers. Although there are many studies worldwide on knowledge, attitudes, and practices (KAP) regarding HPV, research in the Philippines is still limited. This study assessed the knowledge, attitudes, and practices (KAP) of senior high school students in Manila regarding HPV infection and vaccination.
METHODSA descriptive cross-sectional survey was conducted among 345 senior high school students from a private tertiary school in Manila using a self-administered questionnaire. Frequencies and percentages summarized demographic characteristics and KAP responses
RESULTSMost respondents demonstrated good knowledge of HPV, with 86.4% recognizing its link to cervical and anal cancer and 86% identifying it as a common sexually transmitted infection. Attitudes toward vaccination were largely positive: 73% expressed willingness to be vaccinated, and 87.8% considered the vaccine safe. However, only 2.6% had been vaccinated. Limited discussions about HPV, misconceptions about gender susceptibility, and low awareness of local vaccine availability contributed to poor uptake. The internet was the primary information source (84.9%).
CONCLUSIONMost respondents demonstrated good knowledge of HPV, with 86.4% recognizing its link to cervical and anal cancer and 86% identifying it as a common sexually transmitted infection. Attitudes toward vaccination were largely positive: 73% expressed willingness to be vaccinated, and 87.8% considered the vaccine safe. However, only 2.6% had been vaccinated. Limited discussions about HPV, misconceptions about gender susceptibility, and low awareness of local vaccine availability contributed to poor uptake. The internet was the primary information source (84.9%).
Vaccination
7.Association between vaccination status and the incidence of breakthrough COVID-19 infections among University of Santo Tomas – Faculty of Medicine and Surgery students: A case-control study.
Ryan Irvin M. ABUSTAN ; Joaquin V. ABUNDANCIA ; Vincent Rhey L. ACCAD ; Kimberly Mae H. ADVINCULA ; Jillian Elize F. AFABLE ; Vanessa Joy A. AGRAVIADOR ; Ida Marie TABANGAY-LIM
Journal of Medicine University of Santo Tomas 2025;9(S1):75-83
INTRODUCTION
With the introduction of COVID-19 vaccines, schools around the world have slowly started to reimplement on-site classes with guidelines to prevent outbreaks. The University of Santo Tomas has devised their own set of guidelines, including safety protocols, vaccinations and daily health declarations. These were monitored using the
Thomasian Online Medical Services and Support (ThOMedSS).
Through a case-control study design, the study aims to determine an association between the vaccination status of UST Faculty of Medicine and Surgery (UST-FMS) students and breakthrough COVID-19 infections in the first semester of the academic year 2022-2023, with population data acquired via records of students participating in face-to-face classes from the UST Health Service Office, and categorized based on breakthrough infections and vaccination status.
STATISTICAL ANALYSISResults were analyzed using Pearson’s chi-square test and Fisher’s exact test (pCONCLUSION
The study suggests that vaccination status did not have a statistically significant association (p = 0.3451) with breakthrough infections. The majority (99.94%) of students have received the complete primary COVID-19 vaccination series and only 6.61% of this population developed breakthrough COVID-19 infections, all occurring in those completely vaccinated. Breakthrough infections were 1.76 times more likely for those with booster shots than those without. The possible reason for this is the emergence of the Omicron variant. To improve the study, external exposures and individual behaviors must be considered as potential factors influencing infection rates.
Human ; Male ; Female ; Child: 6-12 Yrs Old ; Adolescent: 13-18 Yrs Old ; Young Adult: 19-24 Yrs Old ; Association ; Case-control Studies ; Covid-19 ; General Surgery ; Faculty ; Incidence ; Infections ; Medicine ; Universities ; Vaccination
8.Differences in routine childhood immunization uptake between single and multiple healthcare facility use: the Kochi Adjunct Study of Japan Environment and Children's Study.
Marina MINAMI ; Yoshihiko TERAUCHI ; Masamitsu EITOKU ; Yuki SHIMOTAKE ; Tamami TSUZUKI ; Ryuhei NAGAI ; Nagamasa MAEDA ; Mikiya FUJIEDA ; Narufumi SUGANUMA
Environmental Health and Preventive Medicine 2025;30():51-51
BACKGROUND:
The efficacy of routine childhood immunization depends on timely vaccine uptake and facility use patterns. This study examined the association between pediatric vaccination facility use patterns and routine childhood immunization uptake among children up to age eight years.
METHODS:
As part of the Kochi Adjunct Study of the Japan Environment and Children's Study (JECS), we analyzed data from 1,644 participants whose Maternal and Child Health Handbook photographs were collected in the eighth year of the cohort study. Maternal and Child Health Handbook records determined immunization completion. Participants were categorized into four groups based on pediatric vaccination facility use patterns: single facility use throughout, multiple facility use during the first period, multiple facility use during the second period, and multiple facility use throughout both periods. Maternal and child characteristics were collected via paper-based questionnaires. Associations between facility use patterns, sociodemographic factors, and immunization completion were analyzed using chi-square tests and logistic regression.
RESULTS:
Overall, routine childhood immunization completion was observed in 1,259 (76.6%) participants. Chi-square tests indicated that marital status, educational level, lower parity, never smoking, not attending nursery, and breastfeeding practice for infants aged four months old were significantly associated with routine childhood immunization completion. Single facility use throughout the immunization period was observed in 1,011 (61.5%) participants. Multiple facility use (38.5%) was associated with higher odds of routine childhood immunization incompletion than single facility use. This association was the strongest for those who used multiple facilities throughout the vaccination period (adjusted odds ratio, 1.90; 95% confidence interval, 1.24-2.91).
CONCLUSIONS
Single pediatric facility use was associated with higher routine immunization uptake. Our findings suggest that encouraging the use of one medical institution for a child's vaccinations may be a useful approach to consider when addressing vaccination coverage challenges.
Humans
;
Japan
;
Female
;
Male
;
Infant
;
Child, Preschool
;
Health Facilities/statistics & numerical data*
;
Child
;
Vaccination/statistics & numerical data*
;
Adult
;
Immunization/statistics & numerical data*
;
Cohort Studies
;
Infant, Newborn
9.Estimated coverage of vaccines for children in Japan between 2011 and 2022: a descriptive study utilizing nationwide monthly market data.
Environmental Health and Preventive Medicine 2025;30():79-79
BACKGROUND:
Japan lacks comprehensive reports on the nationwide voluntary vaccine coverage. The effectiveness of public subsidies in promoting vaccination has not been fully investigated. Therefore, we aimed to estimate the nationwide coverage of voluntary vaccines, compare it with that of national immunization program (NIP)-included vaccines, and investigate the effectiveness of public subsidies.
METHODS:
We obtained nationwide monthly vaccine market data for rotavirus, Haemophilus influenzae type b (Hib), diphtheria, tetanus toxoid, acellular pertussis, inactivated poliovirus (DTaP-IPV), and mumps vaccines; estimated recipient numbers; and calculated coverage as the proportion of children from October 2011 to March 2022. Regarding the NIP-included vaccine, we compared vaccine coverage calculated from nationwide annual market data with that estimated by World Health Organization (WHO)/United Nations Children's Fund (UNICEF), using Bland-Altman analysis.
RESULTS:
The estimates of Hib and DTaP-IPV vaccine coverage derived from market data were slightly higher than the WHO/UNICEF estimates, with mean differences of 0.05 (95% CI: 0.02-0.07) for Hib and 0.03 (95% CI: 0.01-0.05) for DTaP-IPV. The coverage of the rotavirus vaccine gradually increased long before the implementation of national subsidies, reaching 0.9 in 2020. Hib vaccine coverage had already achieved 1.0 by January 2012. The coverage of the DTaP-IPV vaccine was approximately 0.6-0.8 in 2013, reaching 1.0 in 2014. The coverage of mumps vaccine increased gradually from 2011 to 2021.
CONCLUSIONS
Despite the possibility of overestimation, our estimates may serve as a valuable surrogate for actual vaccine coverage in Japan. An increasing trend in rotavirus and mumps vaccine coverage was observed when these vaccines were categorized as voluntary. Although vaccination policies differ from country to country, it would be beneficial to share findings on the impact of subsidies in Japan with other countries.
Japan
;
Humans
;
Vaccination Coverage/statistics & numerical data*
;
Infant
;
Immunization Programs/statistics & numerical data*
;
Rotavirus Vaccines
;
Haemophilus Vaccines
;
Child, Preschool
;
Poliovirus Vaccine, Inactivated
;
Vaccines
10.Socio-cultural and technical gaps in rabies control in the Philippines
Gerry Joey P. Laurito II ; Angelika Buenaventura Ramos ; Kimberly Cu
Philippine Journal of Health Research and Development 2025;29(3):100-103
Rabies remains a persistent public health issue in the Philippines, despite the existence of national and local policies and programs aimed at addressing its eradication. The viral disease, which elicits fatality yet is preventable, disproportionately affects rural areas, especially geographically isolated and disadvantaged area due to the junction of socio-cultural and technical challenges. This commentary article explores the myriad of barriers to rabies prevention and control, including poverty, cultural beliefs, limited health literacy, health delivery, and access inequity. However, the implementation of Rabies Act of 2007, which mandates mass vaccination, education, and the establishment of Animal Bite Treatment Centers (ABTCs), has gaps in the implementation that compromises the program’s sustainability and effectiveness. Deep-rooted cultural practices and beliefs delay or, more so replace evidence-informed medical practices, while geographic isolation and underfunded healthcare facilities hinder optimal provision of care. Moreover, interagency coordination and fragmented reporting surveillance systems further complicate effective rabies control. To address the gaps, this paper advocates for a culturally tailored and community-centered One Health approach that addresses both social and technical aspects of rabies prevention. Important recommendations include decentralizing ABTCs, sustaining vaccination programs with local government support and funding, integrating rabies education into schools and community outreach, and intensifying through multisectoral collaboration both government and nongovernment institutions. Achieving a rabies-free country requires not only biomedical interventions but also a holistic approach – equitable access to healthcare, trust building in communities, and long-term political commitment. In this manner, regardless of location and socioeconomic status, it ensures that this viral disease will be controlled and prevented.
Human ; Philippines ; Social Class ; Rabies ; Virus Diseases ; Mass Vaccination


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