1.Ethical considerations for artificial intelligence-enhanced brain-computer interface.
Yuyu CAO ; Yuhang XUE ; Hengyuan YANG ; Fan WANG ; Tianwen LI ; Lei ZHAO ; Yunfa FU
Journal of Biomedical Engineering 2025;42(5):1085-1091
Artificial intelligence-enhanced brain-computer interfaces (BCI) are expected to significantly improve the performance of traditional BCIs in multiple aspects, including usability, user experience, and user satisfaction, particularly in terms of intelligence. However, such AI-integrated or AI-based BCI systems may introduce new ethical issues. This paper first evaluated the potential of AI technology, especially deep learning, in enhancing the performance of BCI systems, including improving decoding accuracy, information transfer rate, real-time performance, and adaptability. Building on this, it was considered that AI-enhanced BCI systems might introduce new or more severe ethical issues compared to traditional BCI systems. These include the possibility of making users' intentions and behaviors more predictable and manipulable, as well as the increased likelihood of technological abuse. The discussion also addressed measures to mitigate the ethical risks associated with these issues. It is hoped that this paper will promote a deeper understanding and reflection on the ethical risks and corresponding regulations of AI-enhanced BCIs.
Brain-Computer Interfaces/ethics*
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Artificial Intelligence/ethics*
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Humans
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Deep Learning
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User-Computer Interface
;
Electroencephalography
2.Comparison of two registration methods for constructing virtual craniodentofacial patients based on cone beam computed tomography images.
Jiahui YE ; Shimin WANG ; Zixuan WANG ; Yunsong LIU ; Yuchun SUN ; Hongqiang YE ; Yongsheng ZHOU
Journal of Peking University(Health Sciences) 2025;57(2):354-359
OBJECTIVE:
To compare the registration accuracy of cone beam computed tomography (CBCT) images while registering to virtual craniodentofacial patients based on soft tissue and the dentition registration method.
METHODS:
Virtual dentofacial patients out of 13 selected participants who needed CBCT scanning were established by impression with a registered-block impression (RBI) based on digital dental images, three-dimensional (3D) facial images and maxillofacial CBCT images. CBCT images were processed in the Mimics software program, establishing the craniofacial virtual patients based on CBCT images (CCTs). Registration between virtual patients from RBI and CCT, using the soft tissue in lower half face (STE) and dentition (DTN) as the reference area, respectively, forming two kinds of virtual craniofacial patients based on digital dental images, 3D facial images and skeletal images of CBCT (hiding the soft tissue and dental casts from CBCT). Three-dimensional deviation analysis was performed in the upper half face and lower half face of facial images from CBCT between two kinds of virtual craniodentofacial patients and compared with 3D facial images from RBI and recorded as root mean square error (RMSE). Paired-t test was used to compare the deviations of RMSEs between the upper and lower half of the face and the upper half of the face of facial images from CCT, respectively, between the two kinds of virtual craniodentofacial patients based on STE and DTN methods.
RESULTS:
Paired-t tests showed that there was no statistically significant difference between the upper and lower half faces of facial images from CCT between STE and DTN (P>0.05), but the deviation of RMSEs of the upper half face of facial images from CCT in STE was smaller than those in DTN [(1.696±0.420) mm vs. (1.752±0.424) mm, P < 0.01].
CONCLUSION
The registration accuracy of CBCT registered in virtual craniodentofacial patients using soft tissue as the reference area was higher.
Humans
;
Cone-Beam Computed Tomography/methods*
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Imaging, Three-Dimensional/methods*
;
Male
;
Face/anatomy & histology*
;
Female
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Adult
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Image Processing, Computer-Assisted/methods*
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Young Adult
;
User-Computer Interface
3.An emerging major: brain-computer interface major.
Hengyuan YANG ; Tianwen LI ; Lei ZHAO ; Xiaogang CHEN ; Jiahui PAN ; Yunfa FU
Journal of Biomedical Engineering 2024;41(6):1257-1264
Brain-computer interface (BCI) is a revolutionizing technology that disrupts traditional human-computer interaction by establishing direct communication and control between the brain and computer, bypassing the peripheral nervous and muscular systems. With the rapid advancement of BCI technology, growing application demands, and an increasing need for specialized BCI professionals, a new academic major-BCI major-has gradually emerged. However, few studies to date have discussed the interdisciplinary nature and training framework of this emerging major. To address this gap, this paper first introduced the application demands of BCI, including the demand for BCI technology in both medical and non-medical fields. The paper also described the interdisciplinary nature of the BCI major and the urgent need for specialized professionals in this field. Subsequently, a training program of the BCI major was presented, with careful consideration of the multidisciplinary nature of BCI research and development, along with recommendations for curriculum structure and credit distribution. Additionally, the facing challenges of the construction of the BCI major were analyzed, and suggested strategies for addressing these challenges were offered. Finally, the future of the BCI major was envisioned. It is hoped that this paper will provide valuable reference for the development and construction of the BCI major.
Brain-Computer Interfaces/trends*
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Humans
;
Electroencephalography
;
User-Computer Interface
4.Ethics considerations on brain-computer interface technology.
Zhe ZHANG ; Xu ZHAO ; Yixin MA ; Peng DING ; Wenya NAN ; Anmin GONG ; Yunfa FU
Journal of Biomedical Engineering 2023;40(2):358-364
The development and potential application of brain-computer interface (BCI) technology is closely related to the human brain, so that the ethical regulation of BCI has become an important issue attracting the consideration of society. Existing literatures have discussed the ethical norms of BCI technology from the perspectives of non-BCI developers and scientific ethics, while few discussions have been launched from the perspective of BCI developers. Therefore, there is a great need to study and discuss the ethical norms of BCI technology from the perspective of BCI developers. In this paper, we present the user-centered and non-harmful BCI technology ethics, and then discuss and look forward on them. This paper argues that human beings can cope with the ethical issues arising from BCI technology, and as BCI technology develops, its ethical norms will be improved continuously. It is expected that this paper can provide thoughts and references for the formulation of ethical norms related to BCI technology.
Humans
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Brain-Computer Interfaces
;
Technology
;
Brain
;
User-Computer Interface
;
Electroencephalography
5.Research on Logic Design of Proton Treatment Control System.
Zhuofan CAI ; Rong XIE ; Jianchun DENG ; Zhiyong YANG
Chinese Journal of Medical Instrumentation 2023;47(4):370-376
The proton treatment control system is the supporting software of the proton therapy device, which specifically coordinates and controls the status and work of each subsystem. In this study, the software architecture and hardware implementation of the proton treatment control system was developed and built a foundation for the overall debugging. Using C# programming language and WPF programming techniques, TCP network communication protocol specified by the proton treatment technical document and MVVM pattern in Windows system, the logic design and implementation of each level were studied. Meanwhile, the communication interface between the subsystems under TCP communication protocol was agreed. The logic design and research of the setup field and treatment field were carried out. And the User Interface was designed and developed using the above technology. The program realizes the communication and interaction between the proton treatment control system and each subsystem, so as to control and monitor the whole treatment process. The proton treatment control system provides a software basis for the remote overall debugging and on-line monitor and control of proton treatment device.
Protons
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User-Computer Interface
;
Software
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Computers
;
Logic
6.Applications, industrial transformation and commercial value of brain-computer interface technology.
Jiangong LUO ; Peng DING ; Anmin GONG ; Guixin TIAN ; Haotian XU ; Lei ZHAO ; Yunfa FU
Journal of Biomedical Engineering 2022;39(2):405-415
Brain-computer interface (BCI) is a revolutionary human-computer interaction technology, which includes both BCI that can output instructions directly from the brain to external devices or machines without relying on the peripheral nerve and muscle system, and BCI that bypasses the peripheral nerve and muscle system and inputs electrical, magnetic, acoustic and optical stimuli or neural feedback directly to the brain from external devices or machines. With the development of BCI technology, it has potential application not only in medical field, but also in non-medical fields, such as education, military, finance, entertainment, smart home and so on. At present, there is little literature on the relevant application of BCI technology, the current situation of BCI industrialization at home and abroad and its commercial value. Therefore, this paper expounds and discusses the above contents, which are expected to provide valuable information for the public and organizations, BCI researchers, BCI industry translators and salespeople, and improve the cognitive level of BCI technology, further promote the application and industrial transformation of BCI technology and enhance the commercial value of BCI, so as to serve mankind better.
Brain/physiology*
;
Brain-Computer Interfaces
;
Electroencephalography
;
Humans
;
Technology
;
User-Computer Interface
7.Research and application of photovoltaic cell online monitoring system for animal robot stimulator.
Yong SHI ; Zhihao YU ; Rui YAN ; Hui WANG ; Junqing YANG ; Ruituo HUAI
Journal of Biomedical Engineering 2022;39(5):974-981
Power supply plays a key role in ensuring animal robots to obtain effective stimulation. To extending the stimulating time, there is a need to apply photovoltaic cells and monitor their parameter variations, which can help operators to obtain the optimal stimulation strategy. In this paper, an online monitoring system of photovoltaic cells for animal robot stimulators was presented. It was composed of battery information sampling circuit, multi-channel neural signal generator, power module and human-computer interaction interface. When the signal generator was working, remote navigation control of animal robot could be achieved, and the battery voltage, current, temperature and electricity information was collected through the battery information sampling circuit and displayed on the human-computer interaction system in real time. If there was any abnormal status, alarm would be activated. The battery parameters were obtained by charging and discharging test. The battery life under different light intensity and the stimulation effect of neural signal generator were tested. Results showed that the sampling errors of battery voltage, current and electric quantity were less than 15 mV, 5 mA and 6 mAh, respectively. Compared with the system without photovoltaic cells, the battery life was extended by 148% at the light intensity of 78 320 lx, solving the battery life problem to some extent. When animal robot was stimulated with this system, left and right turns could be controlled to complete with the success rate more than 80%. It will help researchers to optimize animal robot control strategies through the parameters obtained in this system.
Animals
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Humans
;
Robotics
;
Electric Power Supplies
;
Electricity
;
User-Computer Interface
8.Research advances in non-invasive brain-computer interface control strategies.
Hongtao CAO ; Tzyy-Ping JUNG ; Yuanfang CHEN ; Jie MEI ; Ang LI ; Minpeng XU ; Dong MING
Journal of Biomedical Engineering 2022;39(5):1033-1040
Brain-computer interface (BCI) can establish a direct communications pathway between the human brain and the external devices, which is independent of peripheral nerves and muscles. Compared with invasive BCI, non-invasive BCI has the advantages of low cost, low risk, and ease of operation. In recent years, using non-invasive BCI technology to control devices has gradually evolved into a new type of human-computer interaction manner. Moreover, the control strategy for BCI is an essential component of this manner. First, this study introduced how the brain control techniques were developed and classified. Second, the basic characteristics of direct and shared control strategies were thoroughly explained. And then the benefits and drawbacks of these two strategies were compared and further analyzed. Finally, the development direction and application prospects for non-invasive brain control strategies were suggested.
Humans
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Electroencephalography
;
Brain-Computer Interfaces
;
Communication Aids for Disabled
;
User-Computer Interface
;
Brain/physiology*
9.Human factors engineering of brain-computer interface and its applications: Human-centered brain-computer interface design and evaluation methodology.
Xiaotong LU ; Peng DING ; Siyu LI ; Anmin GONG ; Lei ZHAO ; Qian QIAN ; Lei SU ; Yunfa FU
Journal of Biomedical Engineering 2021;38(2):210-223
Brain-computer interface (BCI) is a revolutionizing human-computer Interaction, which is developing towards the direction of intelligent brain-computer interaction and brain-computer intelligent integration. However, the practical application of BCI is facing great challenges. The maturity of BCI technology has not yet reached the needs of users. The traditional design method of BCI needs to be improved. It is necessary to pay attention to BCI human factors engineering, which plays an important role in narrowing the gap between research and practical application, but it has not attracted enough attention and has not been specifically discussed in depth. Aiming at BCI human factors engineering, this article expounds the design requirements (from users), design ideas, objectives and methods, as well as evaluation indexes of BCI with the human-centred-design. BCI human factors engineering is expected to make BCI system design under different use conditions more in line with human characteristics, abilities and needs, improve the user satisfaction of BCI system, enhance the user experience of BCI system, improve the intelligence of BCI, and make BCI move towards practical application.
Brain
;
Brain-Computer Interfaces
;
Electroencephalography
;
Ergonomics
;
Humans
;
User-Computer Interface
10.Brain-computer interface: from lab to real scene.
Journal of Biomedical Engineering 2021;38(3):405-408
Brain-computer interface (BCI) can be summarized as a system that uses online brain information to realize communication between brain and computer. BCI has experienced nearly half a century of development, although it now has a high degree of awareness in the public, but the application of BCI in the actual scene is still very limited. This collection invited some BCI teams in China to report their efforts to promote BCI from laboratory to real scene. This paper summarizes the main contents of the invited papers, and looks forward to the future of BCI.
Brain
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Brain-Computer Interfaces
;
China
;
Electroencephalography
;
Laboratories
;
User-Computer Interface

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