Background: Neurosyphilis is a severe manifestation of Treponema pallidum infection that may occur at any stage, particularly in cases of inadequate treatment or follow-up. Case Presentation: We report a case of a 55-year-old male with a prior history of treated syphilis who presented with progressive neuropsychiatric symptoms, including memory impairment, disorganized speech, and behavioral changes. Serial serological testing revealed a rising rapid plasma reagin (RPR) titer from 1:2 to 1:32 over time. Cerebrospinal fluid (CSF) analysis demonstrated elevated protein levels and a positive Treponema pallidum hemagglutination assay (TPHA 1:80), confirming the diagnosis of neurosyphilis despite a negative VDRL test in CSF. The patient was initially treated with ceftriaxone, followed by definitive therapy with intravenous benzylpenicillin for 14 days. Subsequent follow-up showed a gradual decline in RPR titers (1:32 to 1:1) along with clinical improvement. Conclusion This case underscores the importance of adequate post-treatment surveillance and highlights the need to consider neurosyphilis in patients presenting with neuropsychiatric symptoms and rising serological titers, even in the absence of positive CSF VDRL findings.

Background: Gout is a chronic inflammatory disorder stemming from metabolic dysfunction, characterized by the accumulation of monosodium urate crystals in joints and soft tissues due to prolonged hyperuricemia. Clinically, it often manifests with abrupt onset of intense joint pain, erythema, swelling, and tenderness, particularly in the small joints of the lower extremities such as the first metatarsophalangeal joint, ankles, and knees. In its chronic form, gout can lead to the development of tophi—firm nodular deposits of urate crystals— resulting in joint deformities, limited mobility, and systemic complications affecting the renal and cardiovascular systems. This case report describes the integrative management of a 68-year-old male patient with a long-standing history of chronic tophaceous gout, presenting with acute exacerbation involving multiple joints and extensive tophaceous deposits. The patient underwent a course of traditional Mongolian medical treatment, incorporating bloodletting therapy (hanuur), soaking therapy (devteeleg zasal), and phytotherapeutic remedies. Conclusion The treatment yielded notable clinical improvements: cupping therapy facilitated the reduction of joint inflammation and edema, alleviated pain, and enhanced peripheral circulation during the acute phase. Soaking therapy using medicated decoctions was effective in softening and reducing the size of tophi, promoting wound drying, restoring joint mobility, and improving overall functional capacity. The patient reported a marked enhancement in quality of life following the integrative treatment course. This case highlights the potential of traditional Mongolian medical interventions as adjunctive or alternative therapeutic strategies for managing severe gout, particularly in cases refractory to conventional pharmacological treatment. Further clinical research and controlled studies are warranted to validate these findings and to explore the broader application of traditional therapies in gout management.

BACKGROUND. Hypertension is an increasingly important medical and public-health issue. Recent years complementary and alternative medicine therapies are getting popular and frequently than medical treatment used by patients with hypertension and cardiovascular disease. Aiming to analyze the efficacy of bloodletting to treat impure blood and hypertension and to implement to the clinical practice. METHODS. 14 day before and after loodletting treatment, triglycerides, cholesterol, high- density lipoprotein were analyzed and compared to body type for 30 patients (30- 60 years old ) who have 1st stage arterial hypertension. The LDL was calculated with Fridvalid formula. The participants took traditional prescription ( formula of three seeds) 2gr twice per day for 5 days after bloodletting vena. ( jinshug) RESULTS. The study showed that triglycerides are decreased by 0,4mml/l (P value 0.0047), cholesterol was decreased by 1,54 mml/l (P value 0.00001), LDL was decreased by 1,68 mml/ l (P value 0.00001), and HDL was increased by 0,22 mml/ l (P value 0.0001) after bloodletting treatment. After treatment we observed decreasing hypertension when measured the systolic and diastolic blood pressure for three months. LDL and cholesterol increasing in the blood is risk for cardiovascular disease. But in this study LDL and cholesterol were decreasing after bloodletting treatment which means it is possible to prevent from cardiovascular disease. As well after treatment HDL was increased in the blood that showed prevention from arteriosclerosis. СONCLUSION. Most of patients were shar and badgan type. The badgan type with patients had obesity and high cholesterol compared to other body types. After treatment cholestrol was decreased in all patients, LDL was decreased and HDL was significantly increased in the badgan type patients with hypertension. Systolic and diastolic blood pressure were decreased and stable and kept for long time after bloodletting treatment.