Schizencephaly is an uncommon, congenital disorder showing developmental cerebral
malformation characterized by clefts in the cerebral cortex, which extends from the ependymal
surface of the ventricle through the white matter to the pial surface. Magnetic resonance
was more sensitive than computed tomography in detecting the clefts [1]. Yakovlev and
Wadsworth first coined the term “schizencephaly” in 1946, in their study on cadavers [2].
Schizencephaly is associated in some cases with microcephaly, hydrocephalus, or other
malformations such as septo-optic dysplasia [1, 3]. This disorder can be detected in vivo
by ultrasonography [4]. Here, we present a rare case of a 9-month-old female infant with
underdevelopment of the right cerebral hemisphere.
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