Background: Nurses play a central role in pain assessment, treatment monitoring, and clinical decision-making. Their competence in pain management and medication safety directly affects the quality and safety of care. Inadequate knowledge increases the risk of pain underassessment, inappropriate medication use, and delayed detection of adverse effects. However, comparative evidence on nursing competencies between the Mongolian–Japanese Hospital (MJH) and the International Mongolian Hospital of Inner Mongolia (IMHOIM) remains limited. Aim: To assess and compare nurses’ levels of pain management knowledge and to examine factors associated with knowledge differences. Materials and Methods: An analytical cross-sectional study was conducted between December 2024 and March 2025, involving 212 nurses from MJH and IMHOIM. Data were collected using the internationally validated Knowledge and Attitudes Survey Regarding Pain (KASRP; 39 items, Cronbach’s α=0.851). Statistical analyses were performed using IBM SPSS Statistics version 26, including descriptive statistics, independent samples t-test, ANOVA, Mann–Whitney U test, Pearson correlation, and stepwise linear regression. Statistical significance was set at p<0.05. Result: Participants differed significantly by age, educational level, professional rank, and years of experience between the two hospitals. The overall mean knowledge score varied significantly by institution, with IMHOIM nurses scoring higher than MJH nurses (26.69±7.55, 19.88±5.21; p<0.001). Domain-specific analysis indicated that IMHOIM nurses outperformed in foundational and pharmacological knowledge, whereas MJH nurses showed superior performance in clinical decision-making and case-based items (p<0.001). Years of experience demonstrated a moderate positive correlation with knowledge scores (r=0.434, p<0.001); however, educational level and professional rank emerged as the strongest independent predictors in regression analysis. Conclusion Nurses’ pain management knowledge differs by institution, reflecting variations in theoretical and clinical competence. Work experience alone is insufficient; higher education, professional rank, and continuous case-based clinical training are critical. Accordingly, pain management education should emphasize evidence-based, clinically oriented programs to strengthen clinical decision-making skills.

Background: Diffuse large B-cell lymphoma (DLBCL) is a common subtype of non-Hodgkin lymphoma of B-lymphocyte origin, characterized by an aggressive clinical course. Clinically, it most often presents with lymphadenopathy and “B symptoms,” including fever, night sweats, and weight loss. However, in some cases, the disease predominantly involves extranodal organs, such as the spleen, and may present with nonspecific manifestations, thereby posing a diagnostic challenge. Case presentation: A 36-year-old male patient presented with high-grade fever of unknown origin, dyspnea, generalized weakness, sweating, and a 7–8 kg weight loss over one month. Clinical evaluation and laboratory investigations revealed massive splenomegaly measuring 15 × 20 × 20 cm, progressive thrombocytopenia, anemia, and elevated C-reactive protein and lactate dehydrogenase levels. Diagnostic workup for infection, tuberculosis, viral infection, and autoimmune disease did not reveal findings sufficient to establish an alternative diagnosis. Because focal splenic lesions and suspected splenic infarction were identified, splenectomy was performed. Histopathological and immunohistochemical examination of the splenic tissue demonstrated CD20+, CD79a+, BCL2+, CD3−, CD8−, CD30−, and ALK− expression, confirming the final diagnosis of diffuse large B-cell lymphoma. Although DLBCL itself is a common form of non-Hodgkin lymphoma, this case is clinically rare and diagnostically challenging because it presented with predominant splenic involvement, massive splenomegaly measuring 15×20×20 cm, treatment-resistant fever, progressive thrombocytopenia, and imaging findings mimicking splenic infarction. Conclusion In patients presenting with fever of unknown origin that is resistant to treatment, massive splenomegaly, thrombocytopenia, elevated LDH, and increased inflammatory markers, lymphoproliferative disorders should be considered early in the differential diagnosis in addition to infectious causes. Histopathological and immunohistochemical examination play a crucial role in confirming the diagnosis.

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease characterized by epidermal barrier dysfunction, immune dysregulation, and significant clinical burden. In Mongolia, research on AD has increased over the past decade; however, findings remain fragmented across various areas. Aim: To synthesize evidence from studies conducted in Mongolia over the last 10 years regarding the pathogenesis, clinical features, diagnosis, and treatment of atopic dermatitis. Materials and Methods: A narrative review was conducted, including original studies on Mongolian populations published within the last decade. Studies addressing skin barrier function, immunological mechanisms, genetic factors, environmental exposures, clinical severity, diagnostic tools, and treatment approaches were included. Results: The study findings show that genetic studies identified polymorphisms in the filaggrin gene and, more recently, mutations in the GCDH gene, suggesting these are linked to AD severity and allergen sensitization. Research on the immunopathogenesis of AD revealed that Th2-type cytokines, especially IL-3 and IL-4, are associated with pruritus and disease severity. Additionally, decreased skin hydration and increased transepidermal water loss in individuals with AD were linked to greater disease severity. Disease severity was evaluated using the SCORAD, EASI, and POEM tools, with most studies reporting that mild-to-moderate AD was most common. Clinically, symptoms like pruritus and sleep disturbances were evident. Additionally, clinical severity was associated with laboratory markers, particularly total IgE levels. The high rate of sensitization to inhalant and food allergens suggests that extrinsic atopic dermatitis (AD) may be common in the Mongolian population. In treatment studies using locally relevant natural products in Mongolia, such as seabuckthorn oil and Shargaljuut mineral spring spray, these products were associated with clinical improvement, suggesting they could serve as additional therapeutic options. Conclusion Research on atopic dermatitis in Mongolia has progressed in several areas; however, the current evidence remains limited and is mostly based on cross-sectional, small-sample, single-center, hospital-based studies. Therefore, there is a need for future comprehensive studies that are multicenter, long-term, and involve larger populations.

Background: The physiology and intellectual traits of individuals are interrelated and should be studied comprehensively. In traditional medicine, the teachings of wind (khi), bile (shar), and phlegm (badgan) are considered an integrated system for maintaining health, preventing diseases, diagnosing, and treating illnesses. Aim: Our research is to study students’ physical indicators, body composition, innate characteristics and the relationship between physique and psychological factors. Materials and Methods: The study was conducted on relatively healthy individuals, did clinical observations and used a cross-sectional study design. (defined as those experiencing internal physiological changes that do not impair their work capacity or active lifestyle) Results: Participants were aged 19-25 years, with an average age of 21.5. Heights ranged from 149 cm to 198 cm, with an average of 165.7 cm. Weights ranged from 37 kg to 111 kg, with an average of 61.55 kg. The Body Mass Index (BMI) varied between 15.3 and 36.3, with an average of 22.36. The majority of participants were female (76.4%), while male participants accounted for 23.6%. Regarding individual constitutional types, the most common were: predominantly bile with wind characteristics (21.2%), predominantly bile with phlegm characteristics (30.8%), predominantly wind with bile characteristics (19.6%). Stress survey results ranged from a minimum score of 0 to a maximum of 50, with an average score of 20.6, indicating slightly below-average psychological well-being. The correlation between physiological traits and psychological survey scores was R=0.323** (p=0.001), showing a weak but positive correlation. This suggests that below-average psychological well-being is only minimally influenced by physiological traits. Conclusion The stress survey results indicated an average score of 20.6, slightly below the normal psychological index. The correlation between constitutional traits and psychological well-being was weak but positive (R=0.323**, p=0.001). This implies that individual constitutional characteristics have a minimal effect on psychological well-being. In the study of intrinsic unique characteristics, it has been found that certain physical constitution metrics of the participants demonstrate both positive and negative correlations with the majority of body types, indicating that individuals exhibit varying physical constitution characteristics. Additionally, there exists a positive but weak correlation between intrinsic unique characteristics and stress levels, warranting further investigation.

Background: Establishment of quantitative reference intervals of white blood cells and its subpopulations using a high accuracy analytic system is essential for clinical medicine, public health, and anthropology. We are unable to identify peer-reviewed literature sources describing white blood cell counts and their subpopulations using monoclonal antibodies to specific surface antigens in healthy Mongolians. This study aimed to measure the counts of white blood cells and their subpopulations in healthy Mongolians using flowcytometry. Materials and Methods: The absolute number (cell/L) of leukocytes (CD45+), granulocytes, monocytes and lymphocytes were measured by Magnetic Activated Cell Sorting Assay (MACSQuant Analyzer 10) in 287 blood donors (158 males and 129 females) 17-64 years of age (mean age 33.1±12.4). Peripheral blood samples were collected at the time of blood donation at the National Center for Transfusion Medicine. Results The mean values of leukocytes and granulocytes were lower in donors over 30 years of age (ANOVA: F=4.408, p=0.002 and F=5.685, p=0.001) and regression analysis demonstrated indirect correlation between counts of these cells and age of donors (r= - 0.198, p=0.001 and r=-0.221, p=0.001, respectively). Gender-related differences in white blood cell counts were not found.
Mean value of lymphocyte count in donors investigated in spring (May and March, n = 87; 2224.6±775.3) was significantly higher than those in winter (December – February, n=180; 1613.2±454.3, p=0.001) and autumn (October, n=20; 1576.1±438.6, p= 0.001).
Comparing of our findings with the data from available literature shown that healthy Mongolians have lower leukocyte count compared with Koreans, Chinese Han population and lower mean value of lymphocyte count comparing with Korean, Chinese Han population, and Arabian (Saudi Arabia) populations.