1.Application of mathematical models for TCM health status analysis, monitoring, early warning, and prevention in the diagnosis and treatment of thyroid diseases
Ziqi JIAO ; Tiefeng SUN ; Na ZHANG ; Yajun ZHANG ; Jialei FU ; Chunlei WANG ; Jingzhi YU
Chinese Journal of Endemiology 2025;44(11):942-946
Thyroid diseases are clinically prevalent endocrine and metabolic disorders, including various types such as Hashimoto's thyroiditis and thyroid nodules. Their pathogenesis is complex and influenced by numerous factors, potentially involving genetic factors, environmental factors, and immune dysfunction. With the continuous advancement of modern traditional Chinese medicine (TCM), TCM has established a unique theoretical system in the prevention and treatment of thyroid diseases, with increasingly rich clinical practical experience. This article reviews the recent application of TCM health status analysis, monitoring, early warning, and prevention in the field of thyroid diseases, aiming to provide useful references for in-depth study in this field.
2.Research progress on the antitumor effects of immune checkpoint inhibitors
Qiang FU ; Zhongqi LU ; Ying CHANG ; Tiefeng JIN ; Meihua ZHANG
The Journal of Practical Medicine 2025;41(2):288-293
Tumor immunotherapy has emerged as a highly esteemed and rapidly evolving field in recent years,marked by the development of numerous significant therapeutic approaches. Among these,immune checkpoint inhibitors stand out as a pivotal strategy,attracting considerable attention due to their substantial research progress. This article provides a comprehensive review of the current research advancements in ten key immune checkpoints related to anti-tumor therapy,including PD-1/PD-L1,CTLA-4,LAG-3,TIM-3,TIGIT,and VISTA. By conducting an in-depth analysis of their mechanisms of action,clinical applications,and future research directions,this review aims to offer valuable insights and guidance for optimizing strategies in tumor immunotherapy.
3.Research progress on the antitumor effects of immune checkpoint inhibitors
Qiang FU ; Zhongqi LU ; Ying CHANG ; Tiefeng JIN ; Meihua ZHANG
The Journal of Practical Medicine 2025;41(2):288-293
Tumor immunotherapy has emerged as a highly esteemed and rapidly evolving field in recent years,marked by the development of numerous significant therapeutic approaches. Among these,immune checkpoint inhibitors stand out as a pivotal strategy,attracting considerable attention due to their substantial research progress. This article provides a comprehensive review of the current research advancements in ten key immune checkpoints related to anti-tumor therapy,including PD-1/PD-L1,CTLA-4,LAG-3,TIM-3,TIGIT,and VISTA. By conducting an in-depth analysis of their mechanisms of action,clinical applications,and future research directions,this review aims to offer valuable insights and guidance for optimizing strategies in tumor immunotherapy.
4.Application of mathematical models for TCM health status analysis, monitoring, early warning, and prevention in the diagnosis and treatment of thyroid diseases
Ziqi JIAO ; Tiefeng SUN ; Na ZHANG ; Yajun ZHANG ; Jialei FU ; Chunlei WANG ; Jingzhi YU
Chinese Journal of Endemiology 2025;44(11):942-946
Thyroid diseases are clinically prevalent endocrine and metabolic disorders, including various types such as Hashimoto's thyroiditis and thyroid nodules. Their pathogenesis is complex and influenced by numerous factors, potentially involving genetic factors, environmental factors, and immune dysfunction. With the continuous advancement of modern traditional Chinese medicine (TCM), TCM has established a unique theoretical system in the prevention and treatment of thyroid diseases, with increasingly rich clinical practical experience. This article reviews the recent application of TCM health status analysis, monitoring, early warning, and prevention in the field of thyroid diseases, aiming to provide useful references for in-depth study in this field.
5.The status quo, problems and reform proposals on salary system of medical personnel in Shanghai
Xueli DU ; Su XU ; Tiefeng XU ; Yanhua NI ; Xiliang LENG ; Lu CHEN ; Guangwen GAO ; Chen FU
Chinese Journal of Health Policy 2015;(8):4-9
The establishment of a scientific salary system is a key measure to improve the incentive and re-straint mechanisms, adjust and optimize the relations of the production, release the reform “bonus”, and is also an important health care reform today. In order to establish a scientific salary system of medical personnel adapting to the health industry characteristics, the paper makes an investigation on the salary level in the years of 2010—2012 in Shanghai, and analyzes the main problems of the present performance pay policy. On this basis, starting from the point of the health industry characteristics, the paper builds the salary system of medical personnel containing the comprehensive budget management, theoretical workload for approval, authorized personnel, performance appraisal and distribution, structural proportion within the industry, fund distribution management through the establishment of the salary level’s average wage and social linkage mechanism, and builds a theoretical framework on salary system of medical personnel in Shanghai.
6.Study on cross-cultural adaptation and health status in medical international students
Li MA ; Tiefeng FU ; Ji QI ; Xiaohong GAO ; Wenli ZHANG ; Xiang LI ; Shuang CAO ; Changyu GAO
Chinese Journal of Medical Education Research 2011;10(11):1379-1382
A descriptive study to investigate the situation of cross-cultural adaptation and health status among medical international students was carried out using cluster sampling method and self-designed questionnaire in Dalian Medical University.148 international students come from 24 countries.There are 5 religions belief among these students.Islam,Catholic,Hindu,Buddhism and Sikhism.The main obstacles of cross-cultural adaptation are language,accommodation and diet.Economic status and stress of interpersonal relationship are also the main causes affecting the physical and mental health of medical international students.

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