Purpose: This study was conducted to determine the influence of hope, self-efficacy, stress coping ability, and communication ability on the resilience of hospital nurses. Methods: The sample of this study comprised 201 nurses working in the general hospital located in Seoul, Korea for the year of 2024. Data were analyzed using SPSS 25.0, and the analyses included descriptive statistics, t-test, Pearson's ANOVA, and multiple regression. Results: The factors associated with the level of nurses' resilience were hope (β=.41, p<.001), communication (β=.33, p<.001) and stress coping ability (β=.15, p=.005). These factors had an explanatory power of 61.5% (F=32.92, p<.001) in resilience. Conclusion In order to improve nurses' resilience, various trainings and programs need to be developed to enhance nurses' hope, stress coping ability and communication.

Purpose: This study was conducted to determine the influence of hope, self-efficacy, stress coping ability, and communication ability on the resilience of hospital nurses. Methods: The sample of this study comprised 201 nurses working in the general hospital located in Seoul, Korea for the year of 2024. Data were analyzed using SPSS 25.0, and the analyses included descriptive statistics, t-test, Pearson's ANOVA, and multiple regression. Results: The factors associated with the level of nurses' resilience were hope (β=.41, p<.001), communication (β=.33, p<.001) and stress coping ability (β=.15, p=.005). These factors had an explanatory power of 61.5% (F=32.92, p<.001) in resilience. Conclusion In order to improve nurses' resilience, various trainings and programs need to be developed to enhance nurses' hope, stress coping ability and communication.

Purpose: This study was conducted to determine the influence of hope, self-efficacy, stress coping ability, and communication ability on the resilience of hospital nurses. Methods: The sample of this study comprised 201 nurses working in the general hospital located in Seoul, Korea for the year of 2024. Data were analyzed using SPSS 25.0, and the analyses included descriptive statistics, t-test, Pearson's ANOVA, and multiple regression. Results: The factors associated with the level of nurses' resilience were hope (β=.41, p<.001), communication (β=.33, p<.001) and stress coping ability (β=.15, p=.005). These factors had an explanatory power of 61.5% (F=32.92, p<.001) in resilience. Conclusion In order to improve nurses' resilience, various trainings and programs need to be developed to enhance nurses' hope, stress coping ability and communication.

Purpose: This study was conducted to determine the influence of hope, self-efficacy, stress coping ability, and communication ability on the resilience of hospital nurses. Methods: The sample of this study comprised 201 nurses working in the general hospital located in Seoul, Korea for the year of 2024. Data were analyzed using SPSS 25.0, and the analyses included descriptive statistics, t-test, Pearson's ANOVA, and multiple regression. Results: The factors associated with the level of nurses' resilience were hope (β=.41, p<.001), communication (β=.33, p<.001) and stress coping ability (β=.15, p=.005). These factors had an explanatory power of 61.5% (F=32.92, p<.001) in resilience. Conclusion In order to improve nurses' resilience, various trainings and programs need to be developed to enhance nurses' hope, stress coping ability and communication.

Purpose: This study was conducted to determine the influence of hope, self-efficacy, stress coping ability, and communication ability on the resilience of hospital nurses. Methods: The sample of this study comprised 201 nurses working in the general hospital located in Seoul, Korea for the year of 2024. Data were analyzed using SPSS 25.0, and the analyses included descriptive statistics, t-test, Pearson's ANOVA, and multiple regression. Results: The factors associated with the level of nurses' resilience were hope (β=.41, p<.001), communication (β=.33, p<.001) and stress coping ability (β=.15, p=.005). These factors had an explanatory power of 61.5% (F=32.92, p<.001) in resilience. Conclusion In order to improve nurses' resilience, various trainings and programs need to be developed to enhance nurses' hope, stress coping ability and communication.

Introduction: The morphology of the condyles changes naturally with age, gender, face type, occlusal force, functional load, malocclusion type, and the right and left sides. Although condylar shape and size differ throughout populations, there have been few investigations on condylar morphology, particularly in the Malaysian population. Methods: This retrospective, observational, cross-sectional survey was conducted at the Oral and Maxillofacial Surgery Clinic of Sarawak General Hospital from September 2021 to March 2022, involving radiographic assessment of condylar morphology from 893 panoramic radiographs. Age, gender, ethnicity and dentition status using Eichner index were extracted from the data. Descriptive statistics were used. Pearson’s chi-square test was used to determine the association between the independent variables (age, gender, ethnicity and dentition status) and the shape of the mandibular condyle. A p-value of < 0.05 was considered statistically significant. Results: Only 450 panoramic radiographs were included in this study. The condyles were outlined and grouped into four categories, namely pointed (40.2%), round (32.8), angled (18.8), and flat (8.2%). Condylar morphology was found to be significantly associated with gender (p<0.005) and insignificant with other independent variables. Conclusion: The findings suggest that the most prevalent condylar morphology among the Sarawak population is the pointed shape, in contrast with other previous studies that reported the round shape condylar morphology as the majority shape.

Classic hypothalamic-pituitary-end-organ feedback loops – the hypothalamic-pituitary-adrenal axis (HPAA), hypothalamic-pituitary-thyroidal axis (HPTA), and hypothalamic-pituitary-gonadal axis (HPGA) – are associated with the neuroendocrine and immune systems in major depressive disorder (MDD). Female patients with MDD present with evident neuroendocrine and immunological changes. Glucocorticoid, thyroid hormone, and reproductive steroid levels fluctuate with menstrual cycles, which might lead to glucocorticoid receptor resistance, impairment of triiodothyronine conversion, and sex hormone secretion disorders. In this review, we summarize the independent and interactive functions of these three axes in female MDD patients. The similar molecular structure of steroids implies an interrelationship between the hypothalamic-pituitary-end-organ axes and the competitive inhibitory effects at the receptor level, especially when considering the HPAA and HPGA.

Purpose: We investigated whether consecutive levels of new emerging renal biomarkers, including serum cystatin C (CysC) and urinary neutrophil gelatinase-associated lipocalin (NGAL)/creatinine (Cr) ratio, were affected by postconceptional age in very-low-birth-weight (VLBW) infants. Methods: Repeatedly measured samples for each infant were divided into four groups according to postnatal age: at birth (stage I), 3 to 7 days postnatally (stage II), 8 to 28 days postnatally (stage III), and >28 days postnatally (stage IV). The association between renal biomarkers and postconceptional age was assessed using Pearson’s correlation coefficient, and the mean values of renal biomarkers in the four stages were compared using repeated-measures analysis of variance. Results: For samples measured at birth, serum CysC (r=–0.358, P=0.032) and urinary NGAL/Cr ratio (r=–0.522, P=0.001) were negatively correlated with gestational age, whereas serum Cr (r=0.148, P=0.390) was not. In addition, for all samples measured, serum CysC (r=–0.209, P=0.012), urinary NGAL/Cr ratio (r=–0.536, P<0.001), and serum Cr (r=–0.311, P<0.001) were negatively correlated with postconceptional age. Compared with the mean values of the postnatal age-specific stages, serum CysC showed no significant differences in any of the four stages. However, the urinary NGAL/Cr ratio in stage IV was significantly different from those in stages I to III. Conclusion Although urinary NGAL/Cr ratio and serum CysC were negatively correlated with postconceptional age considering renal development, serum CysC showed no significant differences in any of the four postnatal age-specific stages. Urinary NGAL/Cr ratio at >28 days postnatally seems to be more affected by postconceptional age than serum CysC in VLBW infants.

Purpose: We investigated whether consecutive levels of new emerging renal biomarkers, including serum cystatin C (CysC) and urinary neutrophil gelatinase-associated lipocalin (NGAL)/creatinine (Cr) ratio, were affected by postconceptional age in very-low-birth-weight (VLBW) infants. Methods: Repeatedly measured samples for each infant were divided into four groups according to postnatal age: at birth (stage I), 3 to 7 days postnatally (stage II), 8 to 28 days postnatally (stage III), and >28 days postnatally (stage IV). The association between renal biomarkers and postconceptional age was assessed using Pearson’s correlation coefficient, and the mean values of renal biomarkers in the four stages were compared using repeated-measures analysis of variance. Results: For samples measured at birth, serum CysC (r=–0.358, P=0.032) and urinary NGAL/Cr ratio (r=–0.522, P=0.001) were negatively correlated with gestational age, whereas serum Cr (r=0.148, P=0.390) was not. In addition, for all samples measured, serum CysC (r=–0.209, P=0.012), urinary NGAL/Cr ratio (r=–0.536, P<0.001), and serum Cr (r=–0.311, P<0.001) were negatively correlated with postconceptional age. Compared with the mean values of the postnatal age-specific stages, serum CysC showed no significant differences in any of the four stages. However, the urinary NGAL/Cr ratio in stage IV was significantly different from those in stages I to III. Conclusion Although urinary NGAL/Cr ratio and serum CysC were negatively correlated with postconceptional age considering renal development, serum CysC showed no significant differences in any of the four postnatal age-specific stages. Urinary NGAL/Cr ratio at >28 days postnatally seems to be more affected by postconceptional age than serum CysC in VLBW infants.

Background: Neuropathic pain (NP) is considered a clinically incurable condition despite various treatment options due to its diverse causes and complicated disease mechanisms. Since the early 2000s, multipotent human mesenchymal stem cells (hMSCs) have been used in the treatment of NP in animal models. However, the effects of hMSC injections have not been studied in chronic post-ischemia pain (CPIP) mice models. Here, we investigated whether intrathecal (IT) and intrapaw (IP) injections of hMSCs can reduce mechanical allodynia in CPIP model mice. Methods: Seventeen CPIP C57/BL6 mice were selected and randomized into four groups: IT sham (n = 4), IT stem (n = 5), IP sham (n = 4), and IP stem (n = 4). Mice in the IT sham and IT stem groups received an injection of 5 μL saline and 2 × 104 hMSCs, respectively, while mice in the IP sham and IP stem groups received an injection of 5 μL saline and 2 × 10 5 hMSCs, respectively. Mechanical allodynia was assessed using von Frey filaments from pre-injection to 30 days post-injection. Glial fibrillary acidic protein (GFAP) expression in the spinal cord and dorsal root ganglia were also evaluated. Results: IT and IP injections of hMSCs improved mechanical allodynia. GFAP expression was decreased on day 25 post-injection compared with the sham group. Injections of hMSCs improved allodynia and GFAP expression was decreased compared with the sham group. Conclusions These results suggested that hMSCs may be also another treatment modality in NP model by ischemia-reperfusion.