ObjectiveTo investigate the measurement invariance and the score distribution characters of the 9-item Patient Health Questionnaire （PHQ-9）， and to test its feasibility in comparing depression among adolescents of different sexes and ages. MethodsFrom September 2018 to May 2019， 12 241 adolescents aged 10 to 19 years old across 22 primary and secondary schools in Hangzhou were included based on cluster sampling method， and they were investigated by PHQ-9. The measurement invariance was tested by multi-group confirmatory factor analysis. Poisson regression analysis and Logistic regression analysis were adopted to explore the score distribution of PHQ-9 by sex and age. ResultsThe configural， metric， scalar and strict invariances （χ²=2 492.527， df=79， P<0.01， RMSEA=0.071， SRMR=0.031， CFI=0.942， TLI=0.947， ΔCFI=0.004， ΔTLI=0.002 compared with the scalar model） of PHQ-9 across sex were all acceptable， and the configural， metric and scalar invariances （χ²=3 311.991， df=414， P<0.01， RMSEA=0.076， SRMR=0.055， CFI=0.928， TLI=0.937， ΔCFI=0.010， ΔTLI=0.002 compared with the metric model） across age were acceptable. The detection rate of mild depressive symptoms in girls was higher than that in boys （52.99% vs. 46.65%， χ²=48.344， P<0.01）. The PHQ-9 total scores of girls aged 13 to 17 were higher than those of boys （D=0.092~0.144， P<0.01）. There was an interaction between sex and age （χ²=32.800， df=1， P<0.01， OR=0.895）. Except low self-evaluation and suicide or self-injury， the detection rate of assessed symptom on each item of girls was higher than that of boys （P<0.05）. ConclusionIt is discovered that PHQ-9 has measurement equivalence across sex and age in adolescents， and girls and older adolescents scored higher in PHQ-9.

Objective To investigate the effects of hyperbaric oxygen ( HBO) on serum intercellular adhesion molecule 1 (sICAM-1) and S100B proteins in the newborns with hypoxic ischemic encephalopathy ( HIE ) . Methods Sixty-two HIE newborns admitted to the hospital from May 2016 to January 2019 were selected as research subjects. According to the random cluster method, they were divided into the observation group and the control group, each consisting of 31 patients. The control group was given routine treatment, while the observation group received HBO in addition to the treatment received by the control group. Ten days after treatment, the levels of NBNA, nerve reflex and consciousness recovery time, sICAM-1, S100B protein expression and adverse reactions were compared between the patients of the 2 groups. Results Ten days after treatment, the NBNA scores of the 2 groups were all significantly higher than those before treatment. The NBNA scores of the observation group (30. 18 ± 5. 04) was obviously higher than those of the control group (24. 59 ± 5.14), with statistical significance (P < 0. 05). Nerve reflex and consciousness recovery time of the observationgroup[(3.88±1.23),(2.45±0.94)d] wereallsignificantlyshorterthanthoseofthecontrol group [(5. 69 ± 1. 37),(4. 17 ± 1. 13)d], also with statistical significance (P<0. 05). The expression levels of sICAM-1 and S100B in the patients of the 2 groups all decreased obviously as compared with those before treatment, and the levels of the observation group after treatment were evidently shorter than those of the control group, also with statistical significance (P<0. 05). During the course of treatment, total rate of adverse reactions in the observation group was higher (12. 9％) than that of the control group (9. 7％), but without statistical significance (P>0. 05). Conclusion HBO could improve the therapeutic effects on neonatal hypoxic ischemic encephalopathy and decrease the expression levels of SICAM-1 and S100B proteins.

Objective To investigate the effects of hyperbaric oxygen ( HBO) on serum intercellular adhesion molecule 1 (sICAM-1) and S100B proteins in the newborns with hypoxic ischemic encephalopathy ( HIE ) . Methods Sixty-two HIE newborns admitted to the hospital from May 2016 to January 2019 were selected as research subjects. According to the random cluster method, they were divided into the observation group and the control group, each consisting of 31 patients. The control group was given routine treatment, while the observation group received HBO in addition to the treatment received by the control group. Ten days after treatment, the levels of NBNA, nerve reflex and consciousness recovery time, sICAM-1, S100B protein expression and adverse reactions were compared between the patients of the 2 groups. Results Ten days after treatment, the NBNA scores of the 2 groups were all significantly higher than those before treatment. The NBNA scores of the observation group (30. 18 ± 5. 04) was obviously higher than those of the control group (24. 59 ± 5.14), with statistical significance (P < 0. 05). Nerve reflex and consciousness recovery time of the observationgroup[(3.88±1.23),(2.45±0.94)d] wereallsignificantlyshorterthanthoseofthecontrol group [(5. 69 ± 1. 37),(4. 17 ± 1. 13)d], also with statistical significance (P<0. 05). The expression levels of sICAM-1 and S100B in the patients of the 2 groups all decreased obviously as compared with those before treatment, and the levels of the observation group after treatment were evidently shorter than those of the control group, also with statistical significance (P<0. 05). During the course of treatment, total rate of adverse reactions in the observation group was higher (12. 9％) than that of the control group (9. 7％), but without statistical significance (P>0. 05). Conclusion HBO could improve the therapeutic effects on neonatal hypoxic ischemic encephalopathy and decrease the expression levels of SICAM-1 and S100B proteins.

OBJECTIVE: To investigate the sleep monitoring feature of the MSMS in elderly patients with OSAHS. METHOD: One hundred and ninety patients diagnosed with OSAHS were divided into elderly group and non elderly group according to age, then the results of MSMS were analyzed. RESULT: Majority elderly patients were with mild to moderate OSAHS. The nocturnal mean blood oxygen and the lowest oxygen were higher than non elderly group, coupled with higher percentage of the total oxygen saturation < 90% monitoring time (TS90). There was no significant difference in sleep structure between two groups, but the total sleep time of elderly group is lower than the non elderly group, the difference is statistically significant. CONCLUSION The elderly patients with OSAHS were less severe in nature, but the nocturnal hypoxia last longer in the elderly group. There is no significant difference in the sleep structure between the two groups. But the total sleep time decrease in elderly group. With smaller interference, the MSMS is closer to the natural sleep stustus of the subjects.
Aged ; Humans ; Hypoxia ; diagnosis ; Oxygen ; physiology ; Polysomnography ; Sleep ; Sleep Apnea, Obstructive ; diagnosis

OBJECTIVE: To assess the therapeutic effect and study the role of nasal mucosa epithelization after endoscopic surgery using the plasma radiofrequency ablation at low temperature in patients with nasal inverted papilloma. METHOD: The clinical data of 104 patients with nasal inverted papilloma underwent endoscopic surgery u sing the plasma radiofrequency ablation at low temperature from July, 2008 to July, 2012 were analyzed,and the recovery of mucosa was observed under nasal endoscope. RESULT: The mucosa recovery extent showed a decreasing trend from mucosa pattern degree I to III, where the difference was statistically significant by chi-square test between groups (P < 0.05). The average epithelialization time was 2.7 months. It showed a significantly decreasing trend among average epithelialization time of different degrees of mucosa (P < 0.05). The nasal mucosa of most patients completed epithelialization 2.9 months after surgery. CONCLUSION It is safe and effective to treat nasal inverted papilloma with plasma radiofrequency ablation at low temperature. The patients should be followed up with regular reexamination for at least three months after surgery.
Adult ; Aged ; Aged, 80 and over ; Catheter Ablation ; Endoscopy ; Female ; Humans ; Male ; Middle Aged ; Nasal Cavity ; Nasal Mucosa ; pathology ; Nose Neoplasms ; surgery ; Papilloma, Inverted ; surgery ; Postoperative Period ; Retrospective Studies

Obiective To study the compartment environmental quality of ambulance against biological contamination for safe and comfortable transportation and treatment of patients. Methods The experimental research and numerical simulation were carried to master the state of compartment environmental quality, Results Compartment environment indexes excel technology demands, such as overpressure/negative-pressure, temperature, biological contamination, vibration and shock as well as noise and luminance, Conclusion The compartment environmental quality of this ambulance is in a good state.

Objective To analyse and solve the difficulties and countermeasures in continuously proving medical gas. Methods Aiming at the difficulties of continuously proving medical gas, oxygen produced are mostly canned by oxygen compressor, and are transported to every function module through connecting oxygen jars. Results Medical gas module was taken into full play to meet reasonable demand for continuously providing oxygen. Conclusion It is suitable for other field module hospital to use for reference in the action of medical succor of disaster.

This paper introduces the application of motor medical equipment independently developed by ourselves in combined medical succor action between China and Gabon.Problems about equipment using are summarized,and the corresponding resolvent to every different problem is listed,which will help to provide some references to the evolution,demonstration and development of medical equipment in the future.

Objective: To investigate the influence of Icarrin(ICA) on transforming growth factor ?2(TGF?2) expression by PG cells and the mechanisms of reversion of TGF?2 mediated immunosuppression by ICA.Methods: Cell proliferation and cytotoxici- ty were assayed by MTT assay. mRNA level of TGF?2 and perforin was detected by RT-PCR assay. assay.Expression of TGF?2 and IL- 2R? was analysed by folw cytometry assay. Results: ICA could inhibit the protein and mRNA expression of TGF?2 in PG cells. It could also reverse the supressed cytotoxicity of LAK, CD3AK cells by TGF?2. The IL-2R? expression on LAK and perforin gene transcription and proliferation of CD3AK inhibited by TGF?2 were also partly recovered. Conclusion: The anti-anti-tumor activity of ICA is at least partly due to its capability of inhibiting TGF?2 expression in tumor cells and restoring the cytotoxicity of immunocompetent cells inhibited by TGF?2.