Purpose To evaluate right ventricular function before and after the implantation of left ventricular assist device(LVAD)based on ultrasound tissue-tracking strain technique.Materials and Methods We collected data from 15 patients who underwent LVAD surgery from September 2021 to December 2023 in Henan Provincial Chest Hospital.A retrospective analysis was performed on various parameters,including right ventricular free wall strain,right ventricular global longitudinal strain,right ventricular fractional area change,tricuspid annular plane systolic excursion,tricuspid annulus motion spectrum S'peak and intracardiac structural changes,both before surgery and at 1 and 3 months post-surgery.Results Among the 15 LVAD patients,the surgical success rate was 93%.One patient died from acute heart failure following implantation,while the remaining 14 patients recovered well post-surgery.In the 14 patients,the right ventricular free wall strain gradually decreased in the basal,middle and apical segments both before and after surgery,with a more significant reduction in the apical segment.Specifically,the strain decreased at 1 and 3 months post-surgery compared to before surgery[15.80(7.00),8.47(4.90),12.00(5.20)],and showed a significant increase at 3 months post-surgery compared to 1 month post-surgery(all P<0.05).Additionally,the tricuspid annulus displacement of the right ventricle decreased post-surgery(P<0.05).Notably,the size of the left atrium and ventricle significantly decreased at 1 and 3 months post-surgery compared to before surgery,with statistical significance(P<0.05).Meanwhile,the right ventricular fractional area change and the size of the right ventricle was slightly larger than pre-surgery values,without statistical significance(P>0.05).There was no statistically significant change in left ventricular ejection fractions before and after surgery(P>0.05).Conclusion Right ventricular function decreases after LVAD surgery,gradually improving after 3 months,and changes in right ventricular free wall strain parameters are more sensitive.

Purpose To evaluate right ventricular function before and after the implantation of left ventricular assist device(LVAD)based on ultrasound tissue-tracking strain technique.Materials and Methods We collected data from 15 patients who underwent LVAD surgery from September 2021 to December 2023 in Henan Provincial Chest Hospital.A retrospective analysis was performed on various parameters,including right ventricular free wall strain,right ventricular global longitudinal strain,right ventricular fractional area change,tricuspid annular plane systolic excursion,tricuspid annulus motion spectrum S'peak and intracardiac structural changes,both before surgery and at 1 and 3 months post-surgery.Results Among the 15 LVAD patients,the surgical success rate was 93%.One patient died from acute heart failure following implantation,while the remaining 14 patients recovered well post-surgery.In the 14 patients,the right ventricular free wall strain gradually decreased in the basal,middle and apical segments both before and after surgery,with a more significant reduction in the apical segment.Specifically,the strain decreased at 1 and 3 months post-surgery compared to before surgery[15.80(7.00),8.47(4.90),12.00(5.20)],and showed a significant increase at 3 months post-surgery compared to 1 month post-surgery(all P<0.05).Additionally,the tricuspid annulus displacement of the right ventricle decreased post-surgery(P<0.05).Notably,the size of the left atrium and ventricle significantly decreased at 1 and 3 months post-surgery compared to before surgery,with statistical significance(P<0.05).Meanwhile,the right ventricular fractional area change and the size of the right ventricle was slightly larger than pre-surgery values,without statistical significance(P>0.05).There was no statistically significant change in left ventricular ejection fractions before and after surgery(P>0.05).Conclusion Right ventricular function decreases after LVAD surgery,gradually improving after 3 months,and changes in right ventricular free wall strain parameters are more sensitive.

Objective:To evaluate the detection performance of left ventricular ejection fraction (LVEF) in patients with chronic renal failure (CRF) by an artificial intelligence (AI) model based on yolox framework integrating left ventricular segmentation and critical point detection.Methods:From January 2019 to June 2023, a total of 4 284 echocardiographic images of 2 000 adults aged 18-80 years without segmental wall motion abnormalities, structural heart disease, cardiac surgery or cardiomyopathy were collected in Henan Provincial People′s Hospital to delineate the endocardial membrane, as a training set, an AI model based on yolox framework integrating left ventricular segmentation and critical point detection was established. The images were divided into the training set( n=1 675) and the test set( n=325) in a ratio of about 5∶1. All 228 echocardiographic images of 100 normal adult volunteers who were treated in Henan Provincial Chest Hospital from May 2020 to May 2021 were collected as external test set validation. All 792 echocardiographic images of 204 patients treated in Henan Provincial People′s Hospital from April 2019 to June 2023 were continuously enrolled to evaluate the measurement efficiency of AI model. Spearman correlation statistical method was used to analyze the consistency of AI model measurement with manual measurement and TomTec software measurement methods of 3 senior echocardiographic professionals. Subjects were divided into clear image group, unclear image group, normal LVEF group and reduced LVEF group, the differences of general data between the two groups were compared. The correlation coefficient(ICC) within the group was calculated to analyze the consistency, so as to evaluate the model performance. Results:LVEF measured by AI model was significantly correlated with both manual measurement and TomTec model measurement ( rs=0.834, 0.826; all P<0.01). ICC values of the clear image group and the unclear image group were 0.96 and 0.97, respectively. ICC values for all subjects, normal LVEF group and reduced LVEF group were 0.96, 0.90 and 0.96, respectively. Conclusions:The AI model based on yolox framework integrating left ventricular segmentation and critical point detection has good diagnostic performance in the automatic measurement of LVEF in patients with CRF.

Purpose To evaluate the changes of carotid artery elasticity in children with type 1 diabetes mellitus (T1DM) via RF-data based quantitative analysis on vessel stiffness technique (R-VQS),and to detect its correlation with the duration of diabetes mellitus and blood sugar control. Materials and Methods A total of 75 children with T1DM from the Pediatrics Department of Henan Chest Hospital,the Pediatrics Department of Henan People's Hospital,and the Endocrinology,Genetics,and Metabolism Department of Henan Children's Hospital were prospectively collected from September 2019 to November 2021. According to the T1DM duration,all patients were divided into long course group (duration ≥5 years,n=30 cases) and short course group (duration<5 years,n=45 cases). And 30 age and sex matched controls were also collected. The systolic diameter (Diam),vascular displacement (Dist),pulse wave velocity (PWV),stiffness coefficient (HC) and intima-media thickness (IMT) of common carotid artery were measured by R-VQS. Fasting blood glucose (FBG),glycosylated hemoglobin (HbA1c),triglyceride (TG),serum total cholesterol (TC),high-density lipoprotein (HDL),low-density lipoprotein cholesterol (LDL) were collected to compared the differences of parameters among the three groups. Results The FBG,HbA1c and IMT of the long and short course groups were all significantly higher than those of control group (all P<0.05). There were statistically significant differences in PWV and HC among the three groups (F=22.854,P<0.001;F=16.811,P<0.001;H=33.214,P<0.001). The course of disease was moderately correlated with PWV and HC (r=0.621,0.517,respectively,P<0.001). HbA1c was moderately correlated with PWV (r=0.562,P<0.001). Conclusion Early onset of T1DM in children may lead to decreased carotid artery elasticity,and prolonged hyperglycemia can aggravate the degree of arterial elasticity damage. R-VQS is a simple,effective,and non-invasive method for assessing arterial elasticity,providing a basis for clinical diagnosis and treatment.

Purpose To evaluate the changes of carotid artery elasticity in children with type 1 diabetes mellitus (T1DM) via RF-data based quantitative analysis on vessel stiffness technique (R-VQS),and to detect its correlation with the duration of diabetes mellitus and blood sugar control. Materials and Methods A total of 75 children with T1DM from the Pediatrics Department of Henan Chest Hospital,the Pediatrics Department of Henan People's Hospital,and the Endocrinology,Genetics,and Metabolism Department of Henan Children's Hospital were prospectively collected from September 2019 to November 2021. According to the T1DM duration,all patients were divided into long course group (duration ≥5 years,n=30 cases) and short course group (duration<5 years,n=45 cases). And 30 age and sex matched controls were also collected. The systolic diameter (Diam),vascular displacement (Dist),pulse wave velocity (PWV),stiffness coefficient (HC) and intima-media thickness (IMT) of common carotid artery were measured by R-VQS. Fasting blood glucose (FBG),glycosylated hemoglobin (HbA1c),triglyceride (TG),serum total cholesterol (TC),high-density lipoprotein (HDL),low-density lipoprotein cholesterol (LDL) were collected to compared the differences of parameters among the three groups. Results The FBG,HbA1c and IMT of the long and short course groups were all significantly higher than those of control group (all P<0.05). There were statistically significant differences in PWV and HC among the three groups (F=22.854,P<0.001;F=16.811,P<0.001;H=33.214,P<0.001). The course of disease was moderately correlated with PWV and HC (r=0.621,0.517,respectively,P<0.001). HbA1c was moderately correlated with PWV (r=0.562,P<0.001). Conclusion Early onset of T1DM in children may lead to decreased carotid artery elasticity,and prolonged hyperglycemia can aggravate the degree of arterial elasticity damage. R-VQS is a simple,effective,and non-invasive method for assessing arterial elasticity,providing a basis for clinical diagnosis and treatment.

Objective To quantitatively assess left ventricular global systolic and diastolic function using volume-time curves (VTC) by real-time three-dimensional echoeardiography(RT-3DE).Methods Ninty-eight subjects were divided into four groups.Group A consisted of twenty-eight normal subject,group B included twenty-four patients with hypertensive(HTN), group C consisted of twenty-four patients with coronary artery disease(CAD) and group D of twenty-two patients having dilated cordiomyopathy (DCM).Participants were selected undergoing full volume RT-3DE.The global and 17-segmental VTCs were obtained by the off-line Qlab software.The end-diastolic volume(EDV), end-systolic volume(ESV) and ejection fraction(EF) were derived from VTCs.The peak ejection rate(PER),peak early filling rate (PFR),PER/EDV and PFR/EDV were calculted.Results EDV and ESV of group B,C and D was significantly larger than that of group A(all P < 0.05), EF and PER/EDV of group C and D significantly lower than those of group A.There were close correlation between PER/EDV and EF ( r=0.694, P＜0.05).Comparison of VTC pattern of HTN,CAD and DCM with that of healthy participants revealed the loss of symmetry of systolic and diastolic pattern.Conclusions Generation of VTCs by RT3DE is a promising approach to evaluate left ventricular global systolic and diastolic function.PER/EDV and PFR/EDV may be potential parameters for assessing left ventricular global systolic and diastolic function.