1.New Onset SIADH Masquerading Disease Progression during Treatment of Esthesioneuroblastoma
Aashita ; Vikas YADAV ; Rajiv SHARMA ; Pragyat THAKUR
Clinical Pediatric Hematology-Oncology 2024;31(2):41-46
Esthesioneuroblastoma (ENB) is a slow growing malignant tumour of olfactory neuro-epithelium that is locally aggressive with a tendency to recur years later.Infrequently, it can be associated with paraneoplastic syndrome. Here, we a report a pediatric case of ENB in whom syndrome of inappropriate ADH secretion (SIADH) was detected during ongoing primary treatment which reflected disease progression after initial response to chemotherapy, that was substantiated radiologically. SIADH has been reported in only a few cases of ENB.
2.New Onset SIADH Masquerading Disease Progression during Treatment of Esthesioneuroblastoma
Aashita ; Vikas YADAV ; Rajiv SHARMA ; Pragyat THAKUR
Clinical Pediatric Hematology-Oncology 2024;31(2):41-46
Esthesioneuroblastoma (ENB) is a slow growing malignant tumour of olfactory neuro-epithelium that is locally aggressive with a tendency to recur years later.Infrequently, it can be associated with paraneoplastic syndrome. Here, we a report a pediatric case of ENB in whom syndrome of inappropriate ADH secretion (SIADH) was detected during ongoing primary treatment which reflected disease progression after initial response to chemotherapy, that was substantiated radiologically. SIADH has been reported in only a few cases of ENB.
3.New Onset SIADH Masquerading Disease Progression during Treatment of Esthesioneuroblastoma
Aashita ; Vikas YADAV ; Rajiv SHARMA ; Pragyat THAKUR
Clinical Pediatric Hematology-Oncology 2024;31(2):41-46
Esthesioneuroblastoma (ENB) is a slow growing malignant tumour of olfactory neuro-epithelium that is locally aggressive with a tendency to recur years later.Infrequently, it can be associated with paraneoplastic syndrome. Here, we a report a pediatric case of ENB in whom syndrome of inappropriate ADH secretion (SIADH) was detected during ongoing primary treatment which reflected disease progression after initial response to chemotherapy, that was substantiated radiologically. SIADH has been reported in only a few cases of ENB.
4.New Onset SIADH Masquerading Disease Progression during Treatment of Esthesioneuroblastoma
Aashita ; Vikas YADAV ; Rajiv SHARMA ; Pragyat THAKUR
Clinical Pediatric Hematology-Oncology 2024;31(2):41-46
Esthesioneuroblastoma (ENB) is a slow growing malignant tumour of olfactory neuro-epithelium that is locally aggressive with a tendency to recur years later.Infrequently, it can be associated with paraneoplastic syndrome. Here, we a report a pediatric case of ENB in whom syndrome of inappropriate ADH secretion (SIADH) was detected during ongoing primary treatment which reflected disease progression after initial response to chemotherapy, that was substantiated radiologically. SIADH has been reported in only a few cases of ENB.
5.Numbness Following Total Knee Arthroplasty: Role of Incision Length And Position -A Randomized Study
Vikas KULSHRESTHA ; Munish SOOD ; Santhosh KUMAR ; Pardeep KUMAR ; Abin STANLEY ; Prashanth P PADHI ; Saurabh SHARMA
Clinics in Orthopedic Surgery 2023;15(1):59-70
Background:
One of the symptoms annoying patients after total knee replacement (TKR) is numbness around the operative scar. Some studies have shown that altering the incision in terms of placement or length may decrease the incidence of numbness. It still remains unknown whether numbness affects patient-reported outcomes.
Methods:
We conducted a randomized study to compare a short-length incision (n = 50) and a lateral exit incision (n = 50) with a standard midline TKR incision (n = 50) in terms of the incidence of numbness and its progress over 1 year of follow-up. Our secondary objective was to look at the involved zone, area of numbness, and secondary symptoms. We also looked at patient-reported outcome in terms of satisfaction in all groups using a visual analog scale and Forgotten Joint Score.
Results:
At 3 months postoperatively, the incidence of numbness was least in the lateral exit group: 46.2% as compared to midline (62%) and short (58.3%), but the difference was not significant (p = 0.07). At 6 months, the short incision group had a significantly lower incidence (8%) of residual numbness as compared to 30% in the other two groups (p = 0.003). At 1 year, most patients recovered sensation loss and had similar function.
Conclusions
Placement or length of an incision did not significantly affect the incidence of numbness; however, the short incision led to early recovery of numbness. At 1 year of follow-up, most patients did not complain of loss of sensation and had similar functional outcome.
6.Letter to the Editor: An Indian Perspective on Universal Open Access Publishing: Think of the Fire before Venturing Out of the Frying Pan!
Durga Prasanna MISRA ; Vinod RAVINDRAN ; Aman SHARMA ; Anupam WAKHLU ; Sakir AHMED ; Vir Singh NEGI ; Vikas AGARWAL
Journal of Korean Medical Science 2020;35(8):85-
No abstract available.
Fires
;
Open Access Publishing
7.Letter to the Editor: An Indian Perspective on Universal Open Access Publishing: Think of the Fire before Venturing Out of the Frying Pan!
Durga Prasanna MISRA ; Vinod RAVINDRAN ; Aman SHARMA ; Anupam WAKHLU ; Sakir AHMED ; Vir Singh NEGI ; Vikas AGARWAL
Journal of Korean Medical Science 2020;35(8):e85-
8.Gastrointestinal histoplasmosis: a case series from a non-endemic region in North India
Harshal S MANDAVDHARE ; Jimil SHAH ; Kaushal K PRASAD ; Roshan AGARWALA ; Vikas SURI ; Savita KUMARI ; Usha DUTTA ; Vishal SHARMA
Intestinal Research 2019;17(1):149-152
No abstract available.
Histoplasmosis
;
India
9.Retraction: Is treatment with platelet-rich fibrin better than zinc oxide eugenol in cases of established dry socket for controlling pain, reducing inflammation, and improving wound healing?
Sam PAUL ; Rupshikha CHOUDHURY ; Nandini KUMARI ; Sanjay RASTOGI ; Ashish SHARMA ; Vikas SINGH ; Shyamalendu LASKAR ; Tushar DUBEY
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2019;45(6):377-377
This article has been retracted at the request of the Editorial Board.The Editorial Board consulted with the KAMJE (Korean Association of Medical Journal Editors) about ‘Imalas’ matter of the publication and concluded as following:The Paper A is an article on the study of pain, inflammation and formation of granulation tissue using platelet rich fibrin (PRF) for dry socket treatment after tooth extraction. This study was conducted on 100 patients at Teerthankar Mahaveer Dental College and Research Center, Moradabad, from September 2014 to March 2016. The Paper B is a research based on the same conditions as Paper A. This study was conducted on 100 patients using PRF and 100 patients using zinc oxide eugenol, from August 2014 to December 2017. The study was held at the Kothiwal Dental College and Research Centre (KDCRC), Moradabad. The clinical factors studied in above two articles are the same, and the pain scale in Fig. 3 in Paper A is almost identical to the Fig. 2, Group A in Paper B; and Fig. 5 in Paper A is also same as Fig. 4, Group A in Paper B. Both papers are judged to have the overlapping publication in the similar period and the patient, and it is considered intentional not to cite Paper A in Paper B. Therefore, Paper B is believed to be a significant double publication. For this reason, the Editorial Board decided to retracted this article and sincerely apologize for any inconvenience this may have caused.
10.Outcomes of Fast-Track Multidisciplinary Care of Hip Fractures in Veterans: A Geriatric Hip Fracture Program Report
Vikas KULSHRESTHA ; Munish SOOD ; Santhosh KUMAR ; Pramila SHARMA ; Yash Kumar YADAV
Clinics in Orthopedic Surgery 2019;11(4):388-395
BACKGROUND: Hip fractures are a significant cause of morbidity and mortality in the elderly. Fast-track multidisciplinary co-management of these patients, rapid preoperative optimization, early surgery, and expeditious rehabilitation may minimize morbidity and mortality. In this study, we evaluated outcomes of fixation of hip fractures in the elderly patients managed by Geriatric Hip Fracture Program at a military hospital in India. METHODS: A total of 114 patients above 60 years of age with hip fractures were enrolled. They were comanaged by a team of specialists and fast-tracked to surgery. Independent ambulation with support of a walker was achieved before discharge to home. Patients were followed up for 1 year. RESULTS: The average age of the 114 patients was 77 years; 24 patients were octogenarian. Eighty-four percent of injuries were due to a domestic fall. Hypertension (41%) and diabetes (22%) were the most common comorbidities. All patients were optimized before surgery. The average delay from injury to admission was 1.7 days (range, 0 to 14 days) and that from admission to surgery was 1.8 days (range, 0 to 19 days). Hence, the average time from injury to surgery was 3.5 days. The length of stay in hospital was, as per rehabilitative milestones achieved, 2 to 5 days in 40% of the patients and 6 to 15 days in 60% of the patients. At 1 year after surgery, 95 patients were independently ambulant (56 patients with support and 39 patients without support). Twenty-three percent of the patients had postoperative complications and eight patients died (7.7%) at 1-year follow-up; 11 patients were lost to follow-up. CONCLUSIONS: Elderly hip fracture has a high risk of mortality (14%–58%). Thus, expeditious surgery within 24 hours of admission has been advocated in the Western literature to minimize mortality. Mortality rate at 1 year after surgery remains at 10% to 24%. In our study, even with aggressive co-management, the average delay to hip fracture fixation was more than 3 days; however, the 1-year mortality was relatively low (7.7%). This indicates the importance of preoperative optimization and postoperative rehabilitation for independent ambulation and mortality reduction in the elderly population.
Aged
;
Aged, 80 and over
;
Comorbidity
;
Follow-Up Studies
;
Fracture Fixation
;
Hip Fractures
;
Hip
;
Hospitals, Military
;
Humans
;
Hypertension
;
India
;
Length of Stay
;
Lost to Follow-Up
;
Mortality
;
Postoperative Complications
;
Rehabilitation
;
Specialization
;
Veterans
;
Walkers
;
Walking

Result Analysis
Print
Save
E-mail