1.Duodenal Papilla Morphology and ERCP Cannulation difficulties, failure and complications in Manila Doctors Hospital, a tertiary private hospital: A cross-sectional study.
John Christopher A. Onilla ; Sara Jessica B. Pizarras ; Karl Kevin C. Chan ; Manley C. Uy
Journal of the Philippine Medical Association 2023;101(2):15-23
BACKGROUND/OBJECTIVE:
Different major
duodenal papilla morphology pose various challenges of
cannulation and development of ERCP complications.
These morphologies may guide the endoscopist in his
cannulation approach and complication prevention. The
aim of this study is to determine the major duodenal
papilla morphologies of ERCP patients in Manila Doctors
Hospital and their associated cannulation difficulties,
failure, and complications.
METHODS:
This is a retrospective cross-sectional study
of 246 ERCPs at the Manila Doctors Hospital from
January 2017 to December 2018 with naive duodenal
papillae classified according to Watanabe (2019) as
follows: oral protrusion (small, regular, large) and papilla
pattern (annular, unstructured, longitudinal, isolated,
gyrate). Association of papilla morphology with
cannulation difficulties, failure, and complications were
analyzed using logistic regression.
RESULTS:
Among protrusions, small oral protrusions
were more difficult to cannulate compared to regular (OR
0.493, p=0.017) and large protrusions (OR 0.702,
p=0.426). Large protrusions had the highest risk for
failed cannulation (OR 2.04, p=0.445). Among papilla
patterns, unstructured papilla patterns had the highest
risk for difficult (OR 3, p=0.008) and failed cannulation
(OR 7.08, p=0.020). Complications developed in 7 in-
patients with 3 (1.73%) post-ERCP pancreatitis, 1 (0.58%)
post- sphincterotomy bleeding, and 1 (0.58%) cholangitis
and 2 (1.16%) mortalities. One had myocardial infarction
2 days post-ERCP and another had septic shock after 2 days despite endoscopic biliary drainage and antibiotics.
CONCLUSION
Among protrusions, small oral
protrusions had the highest risk for difficult
cannulation while large protrusions had the highest
risk for failed cannulation. Among papilla patterns,
unstructured papilla patterns had the highest risk for
difficult and failed cannulation.
ERCP

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