Objective: To examine the mediating effect of resilience on AIDS-related stress and patient-reported outcome among elderly cases with HIV/AIDS, so as to provide the basis for promoting mental health and improving health outcomes of this population. Methods: From June to July 2024, elderly cases with HIV/AIDS receiving treatment in the infectious diseases department of a tertiary-level hospital in Sichuan Province and undergoing follow-up management at 12 community health service centers in Wuhou District, Chengdu City, Sichuan Province, were selected as study participants using convenience sampling method. Data on demographic information, duration since confirmed diagnosis and the most recent CD4+T lymphocyte count were collected through questionnaire surveys. The Chinese versions of the HIV/AIDS Stress Scale, the Chinese versions of the 10-item Connor-Davidson Resilience Scale, and the Patient-Reported Outcome Scale for Elderly HIV/AIDS Patients were used to assess AIDS-related stress, resilience, and patient-reported outcome, respectively. Structural equation modeling was performed using Mplus 8.3 software to analyze the mediating effect of resilience on AIDS-related stress and patient-reported outcome. The Bootstrap method was employed to test the significance of the mediating effect. Results: A total of 424 elderly HIV/AIDS cases were included, with a mean age of (62.04±8.73) years. Among them, 315 (74.29%) were males and 109 (25.71%) were females. The median scores were 23.00 (interquartile range, 11.00) points for AIDS-related stress, 30.00 (interquartile range, 7.00) points for resilience, and 363.45 (interquartile range, 53.03) points for the total score of patient-reported outcome. Resultsof the mediation effect analysis revealed that AIDS-related stress had a direct negative effect on patient-reported outcome (β=-0.608, 95%CI: -0.742 to -0.465). It also exerted an indirect negative effect on patient-reported outcome through the mediating role of resilience (β=-0.258, 95%CI: -0.364 to -0.158), with the mediating effect accounting for 29.79% of the total effect. Conclusion AIDS-related stress among elderly cases with HIV/AIDS can directly or indirectly negatively affect patient-reported outcome through resilience.

Objective To study and analyze the therapeutic effect of Oza Grey Na (continuous micro pump infusion) on cerebral infarction. Methods 100 patients with cerebral infarction treated in our hospital from February 2015 to August 2016 were selected and randomly divided into the control group and the experimental group, with 50 patients in each group. The patients in the control group received routine treatment, while the experimental group received Oza Grey Na (continuous micro pump) treatment, intravenous drip, 1 courses for 2 weeks. The liver and kidney function, coagulation function, blood routine and other indexes of the patients in the experimental group and the control group were examined before and after treatment, and the therapeutic effects of the two groups were compared and analyzed. Results After treatment, 50 patients in the experimental group were invalid, 3 cases were effective, 20 cases were markedly effective, and the total effective number was 47 cases in 27 cases. Patients in the control group, 8 patients were invalid, 18 patients were effective, 24 patients were markedly effective, and the total effective number was 42 cases. The effective rate of the treatment group was 94％, and the effective rate of the control group was 84％, which was lower than that of the experimental group (P<0.05). There were no severe complications in the experimental group and the control group, and there was no significant difference in the incidence of complications between the 2 groups, and there was no statistical significance. Conclusion Oza Grey Na (continuous micro pump) treatment of cerebral infarction clinical effect is better, more efficient, with further clinical promotion and application of significance.