1.Psychosocial concerns predict longitudinal trajectories of distress in newly diagnosed cancer patients.
Jianlin LIU ; Kevin Fu Yuan LAM ; Rathi MAHENDRAN
Singapore medical journal 2022;63(3):140-146
INTRODUCTION:
Unmet psychosocial concerns are associated with emotional distress among cancer patients. This longitudinal study aimed to identify specific psychosocial concern profiles and trajectories of emotional distress, and examine their association among newly diagnosed adult cancer patients across the first year of diagnosis.
METHODS:
Adult patients aged 21-64 years were screened to determine their eligibility for this study. Psychosocial concerns and psychological distress were measured using the Problem List and the Distress Thermometer, respectively (n = 221). Latent transition mixture analysis was used to determine specific psychosocial concern profiles and trajectories of emotional distress, and examine associations with adjustments made for demographic and medical variables.
RESULTS:
Two classes of psychosocial concerns were identified: low (81%) and high (19%) concerns. Two trajectories of distress were identified: low stable (69%) and high stable (31%) trajectories. Patients in the high concerns class were significantly more likely to demonstrate the high stable trajectory of distress.
CONCLUSION
Our findings highlight the importance of concurrent assessment of multiple psychosocial concerns and screening of emotional distress throughout a cancer patient's treatment journey. Such assessments can effectively guide interventions to address individual concerns and alleviate emotional distress among newly diagnosed cancer patients.
Adult
;
Emotions
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Humans
;
Longitudinal Studies
;
Neoplasms/psychology*
;
Stress, Psychological/psychology*
;
Visual Analog Scale
2.Fear of cancer recurrence among cancer survivors in Singapore.
Rathi MAHENDRAN ; Jianlin LIU ; Sangita KUPARASUNDRAM ; Sebastian SIMARD ; Yiong Huak CHAN ; Ee Heok KUA ; Konstadina GRIVA
Singapore medical journal 2021;62(6):305-310
INTRODUCTION:
Fear of cancer recurrence (FCR) among cancer survivors is a persistent and distressing psychosocial concern that affects recovery and quality of life. The prevalence of FCR in Singapore is unknown. This cross-sectional study was designed to examine FCR and identify factors associated with FCR in mixed-cancer survivors locally.
METHODS:
Cancer survivors in remission (n = 404) were assessed for: FCR using the Fear of Cancer Recurrence Inventory (FCRI); emotional distress using the Hospital Anxiety and Depression Scale; and quality of life using the World Health Organization Quality of Life-BREF. Clinical and severe/pathological FCR was determined based on the severity scale of FCRI, known as FCRI-Short Form. Multivariate logistic regression was performed to examine factors associated with FCR.
RESULTS:
The mean score on the FCRI was 59.5 ± 30.4. 43.6% of cancer survivors had clinical FCR and 32.1% had severe/pathological FCR. Younger age (odds ratio [OR] 0.952, 95% confidence interval [CI] 0.911-0.995, p < 0.05), higher educational status (OR 2.55, 95% CI 1.15-5.65, p < 0.05) and higher levels of emotional distress (OR 1.17, 95% CI 1.10-1.24, p < 0.001) were significantly associated with severe/pathological levels of FCR.
CONCLUSION
The present study is the first to determine levels of FCR among cancer survivors in Singapore. While the total FCR scores were similar to those of international studies, severe/pathological levels of FCR were found to be four times higher. These findings highlight a problem that is not widely recognised or acknowledged, but which deserves greater attention.
3.Successful ageing in Singapore: prevalence and correlates from a national survey of older adults.
Mythily SUBRAMANIAM ; Edimansyah ABDIN ; Janhavi A VAINGANKAR ; Rajeswari SAMBASIVAM ; Esmond SEOW ; Louisa PICCO ; Hong Choon CHUA ; Rathi MAHENDRAN ; Li Ling NG ; Siow Ann CHONG
Singapore medical journal 2019;60(1):22-30
INTRODUCTION:
The current study aimed to estimate the overall prevalence and sociodemographic correlates of successful ageing, as defined by Rowe and Kahn, among a national sample of multiethnic adults aged 60 years and older in Singapore.
METHODS:
Data from older adults who participated in the Well-being of the Singapore Elderly study was analysed. Successful ageing was defined with five indicators: no major diseases; no disability; high cognitive functioning; high physical functioning; and active engagement with life.
RESULTS:
The prevalence of successful ageing was 25.4% in this older population. Older adults aged 75-84 years and ≥ 85 years had 0.3 times and 0.1 times the odds of successful ageing, respectively, than those aged 60-74 years. Compared to older adults of Chinese ethnicity, those of Malay (odds ratio [OR] 0.6) and Indian (OR 0.5) ethnicities were less likely to be associated with successful ageing. Older adults with lower education levels, who had no formal education (OR 0.2), some schooling but did not complete primary education (OR 0.4) or only primary education (OR 0.5), had lower odds of ageing successfully than those with tertiary education.
CONCLUSION
Older adults in Singapore tend to have much more active engagement with life as compared to their counterparts from other countries. Further research into this population is needed, both in terms of qualitative research to gain a better understanding of successful ageing from the older adult's perspective, as well as longitudinal studies that explore behavioural determinants of successful ageing.
Activities of Daily Living
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Aged
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Aged, 80 and over
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Aging
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Cognition
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Cross-Sectional Studies
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Disabled Persons
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Ethnic Groups
;
Female
;
Health Services for the Aged
;
Health Status
;
Humans
;
Independent Living
;
Male
;
Middle Aged
;
Prevalence
;
Singapore
;
Social Class
;
Surveys and Questionnaires
4.Quality of life of family caregivers of cancer patients in Singapore and globally.
Haikel A LIM ; Joyce Ys TAN ; Joanne CHUA ; Russell Kl YOONG ; Siew Eng LIM ; Ee Heok KUA ; Rathi MAHENDRAN
Singapore medical journal 2017;58(5):258-261
INTRODUCTIONFamily caregivers of cancer patients often suffer from impaired quality of life (QOL) due to stress arising from the responsibility of caregiving. Most research on such QOL impairments was conducted in Western populations. Thus, this exploratory study sought to (a) examine the QOL levels of family caregivers of cancer patients in an Asian population in Singapore, in relation to caregivers from other countries within and outside of Asia; and (b) investigate the association between sociodemographic factors and QOL impairments in family caregivers in Singapore.
METHODSA total of 258 family caregivers of cancer patients who were receiving outpatient treatment completed the Caregiver Quality of Life Index-Cancer (CQOLC) and a sociodemographic survey. We compared the published CQOLC total scores from Turkey, Iran, Taiwan, South Korea, the United Kingdom, the United States and Canada with the Singapore dataset and examined the demographic relationships.
RESULTSCaregivers in Singapore and Asia had lower CQOLC total scores than their Western counterparts. Caregivers who were male, of Chinese ethnicity, had parental relationships with their care recipient, or cared for advanced-stage cancer patients were found to have impaired QOL.
CONCLUSIONThe findings of this study highlight possible areas in which support can be provided for family caregivers of cancer patients, and underscore the need to reconcile cultural diversity, values, societal expectations and demographic characteristics in Singapore.
5.Comorbid Diabetes and Depression among Older Adults - Prevalence, Correlates, Disability and Healthcare Utilisation.
Mythily SUBRAMANIAM ; Edimansyah ABDIN ; Janhavi A VAINGANKAR ; Louisa PICCO ; Esmond SEOW ; Boon Yiang CHUA ; Li Ling NG ; Rathi MAHENDRAN ; Hong Choon CHUA ; Derrick Mk HENG ; Siow Ann CHONG
Annals of the Academy of Medicine, Singapore 2017;46(3):91-101
INTRODUCTIONThe objectives of this current study were to: 1) examine the prevalence and correlates of diabetes mellitus (DM) among older adults (aged 60 years and above) in a multi-ethnic population; 2) examine the prevalence and correlates of comorbid DM and depression among them; and 3) assess the effect of comorbid depression on disability, cognition and healthcare utilisation.
MATERIALS AND METHODSData for the current study came from the Well-being of the Singapore Elderly (WiSE) study; a single phase, cross-sectional survey conducted among Singapore residents aged 60 years and above. A total of 2565 respondents completed the survey; depression was assessed using the Automated Geriatric Examination for Computer Assisted Taxonomy (AGECAT) while a diagnosis of DM was considered if respondents stated that a doctor had diagnosed them with DM.
RESULTSDM was reported by 25.5% of the population. The prevalence of depression was significantly higher in those diagnosed with DM than those without DM (6% vs 3%). After adjusting for sociodemographic correlates, smoking and other chronic conditions, DM remained significantly associated with depression and subsyndromal depression. However, after including measures of functioning and cognitive impairment as covariates, DM was not significantly related to depression and subsyndromal depression. Those with comorbid DM and depression were more likely to be of Indian and Malay ethnicity, aged 75 to 84 years (versus 60 to 74 years) and widowed.
CONCLUSIONGiven the significant association of certain sociodemographic groups with comorbid depression among those with DM, targeted interventions for prevention and early diagnosis in these groups should be considered.
Aged ; Aged, 80 and over ; Asian Continental Ancestry Group ; statistics & numerical data ; Comorbidity ; Cross-Sectional Studies ; Depression ; epidemiology ; Depressive Disorder ; epidemiology ; Diabetes Mellitus ; epidemiology ; Ethnic Groups ; statistics & numerical data ; Female ; Health Services ; utilization ; Humans ; India ; ethnology ; Malaysia ; ethnology ; Male ; Middle Aged ; Prevalence ; Severity of Illness Index ; Singapore ; epidemiology ; Surveys and Questionnaires
6.Prevalence of Depression among Older Adults-Results from the Well-being of the Singapore Elderly Study.
Mythily SUBRAMANIAM ; Edimansyah ABDIN ; Rajeswari SAMBASIVAM ; Janhavi A VAINGANKAR ; Louisa PICCO ; Shirlene PANG ; Esmond SEOW ; Boon Yiang CHUA ; Harish MAGADI ; Rathi MAHENDRAN ; Siow Ann CHONG
Annals of the Academy of Medicine, Singapore 2016;45(4):123-133
INTRODUCTIONDepression is a significant public health issue across all sociodemographic groups and is identified as a common and serious mental health problem particularly among the older adult population. The aims of the current study were to determine the prevalence of depression and subsyndromal depression among older adults in Singapore.
MATERIALS AND METHODSThe Well-being of the Singapore Elderly (WiSE) study was a comprehensive single phase, cross-sectional survey. Stage 1 Geriatric Mental State-Automated Geriatric Examination for Computer Assisted Taxonomy (GMS-AGECAT) depression syndrome was used for this analysis. Association of depression and subsyndromal depression with sociodemographic characteristics, social support as well as comorbidity with chronic physical illnesses and quality of life was assessed.
RESULTSThe prevalence of GMS-AGECAT depression and subsyndromal depression was 3.7% and 13.4%, respectively. The odds of depression were significantly higher among those aged 75 to 84 (2.1) as compared to those aged 60 to 74 years and in those who had a history of depression diagnosis by a doctor (4.1). The odds of depression were higher among those of Indian and Malay ethnicities (5.2 and 3.2 times, respectively) as compared to those of Chinese ethnicity. Those with depression and subsyndromal depression were associated with more disability, poorer life satisfaction, and medical comorbidities.
CONCLUSIONOur study suggests that the prevalence of depression seems to have decreased as compared to a decade ago wherein the prevalence of depression was estimated to be 5.5%. This positive trend can be ascribed to concerted efforts across various disciplines and sectors, which need to be continually strengthened, monitored and evaluated.
Aged ; Aged, 80 and over ; Asian Continental Ancestry Group ; China ; Chronic Disease ; Comorbidity ; Cross-Sectional Studies ; Depression ; epidemiology ; Depressive Disorder ; epidemiology ; Ethnic Groups ; statistics & numerical data ; European Continental Ancestry Group ; Female ; Humans ; India ; Malaysia ; Male ; Middle Aged ; Odds Ratio ; Personal Satisfaction ; Prevalence ; Quality of Life ; Singapore ; epidemiology ; Social Support
8.From divination to madness: features of acute intoxication with Salvia use.
Munidasa WINSLOW ; Rathi MAHENDRAN
Singapore medical journal 2014;55(4):e52-3
Salvia divinorum is a psychoactive botanical plant that is increasingly used for the 'legal' highs that it can produce. It is readily available for purchase on the Internet, and most abusers are unaware of the toxicity and abuse potential associated with its use. As the use of novel compounds among abusers is not uncommon, physicians need to increase their awareness and recognition of these new substances. Herein, we report a case of an acute presentation of Salvia intoxication.
Adult
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Fear
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Hallucinations
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chemically induced
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Humans
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Male
;
Plants, Medicinal
;
adverse effects
;
toxicity
;
Salvia
;
adverse effects
;
toxicity
;
Substance-Related Disorders
;
diagnosis
10.Psychosocial care for cancer patients--too little, too late?
Rathi MAHENDRAN ; Joanne CHUA ; Eugene WUAN ; Emily N K ANG ; Siew Eng LIM ; Ee Heok KUA
Annals of the Academy of Medicine, Singapore 2013;42(10):535-537
Assessment of psychosocial and psychiatric needs is an increasingly important component of cancer care. Clinical experience with patients indicate that distress, anxiety and depression are prevalent from early stages of the illness. Strategies to enhance psychosocial care are presented and these include early identification through screening, training for healthcare staff working with cancer patients and support not only for patients but their caregivers as well.
Anxiety
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diagnosis
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Anxiety Disorders
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Caregivers
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Depression
;
diagnosis
;
Humans
;
Neoplasms
;
psychology

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