1.Superior somatic pain relief and improved visceral pain control is achieved using pre-emptive analgesia for laparoscopic cholecystectomy: a randomized controlled trial
Koh PS ; Cha KH ; Lucy C ; Rampal S ; Yoong BK
Journal of University of Malaya Medical Centre 2012;15(2):1-7
BACKGROUND:
Laparoscopic cholecystectomy, although is less invasive than open surgery, is not completely pain free. The
use of local anaesthesia to relieve pain following this procedure is a common practice. However, it remains
debatable whether a pre- or post-operative drug administration is more effective. Here, we investigated
the role of preemptive local anaesthetic infiltration given pre- or post-incisional, in relieving the pain during
laparoscopic surgery.
METHODOLOGY:
A randomized controlled trial was conducted with 96 patients receiving 0.5% Bupivacaine 100mg. Group
A (n=48) received post-incisional skin infiltration whilst Group B (n=48) received pre-incisional infiltration.
Incisional (somatic) and intra-abdominal (visceral) pain was assessed using Visual Analog Scale (VAS) at day
0, day 1 and day 7 post-operative days.
RESULT:
Baseline characteristics between the two groups were similar. Incisional pain was lower in Group B as compared
to Group A at day 0 (P=0.03) and day 1 (P<0.01). Intra-abdominal pain was also lower in Group B at day 0 and
day 1 (P= 0.04). VAS score was similar at day 7 although analgesia requirement is higher in Group A (P>0.05).
CONCLUSION:
Administration of pre-incisional local anaesthesia offers better pre-emptive pain relief measure than postincisional
administration by reducing somatic and visceral pain in laparoscopic gall bladder surgery.
Cholecystectomy, Laparoscopic
2.Construction and validation of a Malay version of the overactive bladder screener for assessing urinary tract symptoms in Malaysian population
Muhilan AP ; S Sivaprakasam ; Dublin N ; S Rampal ; Razack AH ; Thun TH ; Chua CB
Journal of University of Malaya Medical Centre 2009;12(2):74-82
The aim of this study was to validate the translation of the Overactive Bladder (OAB) Screener
(OAB V8) to the Malay language. It was to assess the reliability of the screener in the context of a
Malaysian population. The original screener consists of eight symptoms indicative of OAB that has
been proven to be highly sensitive and reliable. Translation was done with a modification of the
Brislin Method using back translation and a panel of experts as a final review panel. The pilot study
had two groups; a symptomatic (n=19 patients) and an asymptomatic group (n=18 patients). All
patients performed the test twice at two week intervals once at the clinic and subsequently at
home. Test-retest method was used for reliability and Cronbach’s alpha for internal consistency.
The translated questionnaire demonstrated good internal consistency in both groups of patients
for all eight items individually and for the total score. Cronbach’s alphas ranged from 0.972 to
0.981 for the symptomatic group and from 0.750 to 0.976 for the asymptomatic group. Testretest
correlation for all items was highly significant. Intraclass correlation (ICC) was high for both
the asymptomatic (ICC ranging from 0.600 to 0.953) and the symptomatic group (ranging from
0.944 to 0.989).The Malay OAB V8 showed itself to be suitable for use, reliable in distinguishing
symptomatic and asymptomatic patients and a valid instrument.

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