Objective: The present study aimed to detect the behavioral problems pre- and post-cochlear implantation in comparison to normal hearing group to be able to manage these problems to get more benefit from using cochlear implants. Methods: A case-control study included 53 children was done. They were divided into 2 groups, the control group included 28 healthy volunteers with normal hearing and the case group included 25 children with severe to profound hearing loss, fitted for cochlear implantation. The Arabic Child Behavior Checklist (CBCL) was used to detect different behavioral problems in both groups. Case group children were followed up and reassessed again by CBCL 3 months later after cochlear implantation. Results: There were highly significant differences regarding total scores of internalizing and externalizing domains of empirically based CBCL between the control group and the case group after cochlear implants (p=0.001). There were non-significant differences in children within case group (pre- and post-cochlear implantation) regarding emotional and behavioral problems on both empirically based and Diagnostic and Statistical Manual of Mental Disorders-based CBCL. Conclusion For better results, it is necessary to include a specialist of psychosomatic medicine in the cochlear rehabilitation teamwork.

A simple,precise,accurate,and stability-indicating method is developed and validated for analysis of tetrahydrozoline hydrochloride in eye drop formulations.Separation was achieved on a reversed-phase C8 column (125 mm × 4.6 mm i.d.,5 μm) using a mobile phase consisting of acetonitrile/phosphate buffer of pH 3.0 (20∶80,v/v) at a flow rate of 1.0 mL/min and UV detection at 240 nm.This method is validated according to United States Pharmacopeia requirements for new methods,which include accuracy,precision,selectivity,robustness,and linearity and range.This method shows enough selectivity,accuracy,precision,and linearity and range to satisfy Federal Drug Administration/International Conference on Harmonization regulatory requirements.The current method demonstrates good linearity over the range of 0.025-0.075 mg/mL of tetrahydrozoline with r2 0.999.The average recovery of the method is 100.8％ with a relative standard deviation of 0.47％.The degree of reproducibility of the results obtained as a result of small deliberate variations in the method parameters and by changing analytical operators has proven thai the method is robust and rugged.