1.Association Between Functional Dyspepsia and Binge Eating Disorder: A Frequent, Often Overlooked Overlap Clinical Presentation
Francisco A FÉLIX-TÉLLEZ ; Alejandra X CRUZ-SALGADO ; José M REMES-TROCHE ; Ángel R FLORES-RENDON ; Héctor R ORDAZ-ÁLVAREZ ; José A VELARDE-RUIZ VELASCO ; Marco A O FLORES-LIZÁRRAGA ; José I SOTO-GONZÁLEZ ; Nadia S ABIZAID-HERRERA
Journal of Neurogastroenterology and Motility 2025;31(1):95-101
Background/Aims:
This study aims to investigate the association between Binge Eating Disorder and functional dyspepsia in a Mexican population, focusing on symptomatology and demographic characteristics.
Methods:
We conducted a cross-sectional study on 1016 subjects, evaluating binge eating disorder (BED) and functional dyspepsia based on the Rome IV criteria. Data collection included sociodemographic information, gastrointestinal symptom severity, and anxiety/depression screening using validated tools. A multivariate logistic regression analysis with the 2 test was conducted for comparison analysis.
Results:
The prevalence of dyspepsia in BED was 53.6% (95% CI, 46-56). Postprandial fullness (OR, 1.52; 95% CI, 1.06-2.17; P = 0.021) and overlap syndrome (OR, 1.80; 95% CI, 1.25-2.60; P = 0.002) were significantly associated with BED. Patients with BED also presented more severe postprandial distress syndrome (P = 0.027). Anxiety was prevalent in BED patients, while depression was more prominent in patients with BED and dyspepsia overlap.
Conclusions
BED patients have a high prevalence of dyspepsia with an association between postprandial fullness and this eating disorder. BED appears to be more prevalent in younger individuals and males. These findings underscore the importance of considering dyspepsia in the management of BED and highlight the need for further research on this association.
2.Association Between Functional Dyspepsia and Binge Eating Disorder: A Frequent, Often Overlooked Overlap Clinical Presentation
Francisco A FÉLIX-TÉLLEZ ; Alejandra X CRUZ-SALGADO ; José M REMES-TROCHE ; Ángel R FLORES-RENDON ; Héctor R ORDAZ-ÁLVAREZ ; José A VELARDE-RUIZ VELASCO ; Marco A O FLORES-LIZÁRRAGA ; José I SOTO-GONZÁLEZ ; Nadia S ABIZAID-HERRERA
Journal of Neurogastroenterology and Motility 2025;31(1):95-101
Background/Aims:
This study aims to investigate the association between Binge Eating Disorder and functional dyspepsia in a Mexican population, focusing on symptomatology and demographic characteristics.
Methods:
We conducted a cross-sectional study on 1016 subjects, evaluating binge eating disorder (BED) and functional dyspepsia based on the Rome IV criteria. Data collection included sociodemographic information, gastrointestinal symptom severity, and anxiety/depression screening using validated tools. A multivariate logistic regression analysis with the 2 test was conducted for comparison analysis.
Results:
The prevalence of dyspepsia in BED was 53.6% (95% CI, 46-56). Postprandial fullness (OR, 1.52; 95% CI, 1.06-2.17; P = 0.021) and overlap syndrome (OR, 1.80; 95% CI, 1.25-2.60; P = 0.002) were significantly associated with BED. Patients with BED also presented more severe postprandial distress syndrome (P = 0.027). Anxiety was prevalent in BED patients, while depression was more prominent in patients with BED and dyspepsia overlap.
Conclusions
BED patients have a high prevalence of dyspepsia with an association between postprandial fullness and this eating disorder. BED appears to be more prevalent in younger individuals and males. These findings underscore the importance of considering dyspepsia in the management of BED and highlight the need for further research on this association.
3.Association Between Functional Dyspepsia and Binge Eating Disorder: A Frequent, Often Overlooked Overlap Clinical Presentation
Francisco A FÉLIX-TÉLLEZ ; Alejandra X CRUZ-SALGADO ; José M REMES-TROCHE ; Ángel R FLORES-RENDON ; Héctor R ORDAZ-ÁLVAREZ ; José A VELARDE-RUIZ VELASCO ; Marco A O FLORES-LIZÁRRAGA ; José I SOTO-GONZÁLEZ ; Nadia S ABIZAID-HERRERA
Journal of Neurogastroenterology and Motility 2025;31(1):95-101
Background/Aims:
This study aims to investigate the association between Binge Eating Disorder and functional dyspepsia in a Mexican population, focusing on symptomatology and demographic characteristics.
Methods:
We conducted a cross-sectional study on 1016 subjects, evaluating binge eating disorder (BED) and functional dyspepsia based on the Rome IV criteria. Data collection included sociodemographic information, gastrointestinal symptom severity, and anxiety/depression screening using validated tools. A multivariate logistic regression analysis with the 2 test was conducted for comparison analysis.
Results:
The prevalence of dyspepsia in BED was 53.6% (95% CI, 46-56). Postprandial fullness (OR, 1.52; 95% CI, 1.06-2.17; P = 0.021) and overlap syndrome (OR, 1.80; 95% CI, 1.25-2.60; P = 0.002) were significantly associated with BED. Patients with BED also presented more severe postprandial distress syndrome (P = 0.027). Anxiety was prevalent in BED patients, while depression was more prominent in patients with BED and dyspepsia overlap.
Conclusions
BED patients have a high prevalence of dyspepsia with an association between postprandial fullness and this eating disorder. BED appears to be more prevalent in younger individuals and males. These findings underscore the importance of considering dyspepsia in the management of BED and highlight the need for further research on this association.
4.Empyema necessitans presenting as abdominal mass in an adult female: A case report.
Maria Tesalonica R. PITOC ; Haydee D. DANGANAN ; Rosemarie I. GALERA ; Marco Neoman DELA CRUZ ; Faith MANDAPAT- GARCIA
The Filipino Family Physician 2025;63(2):186-190
Empyema Necessitans is a rare complication of Empyema Thoracis that is caused by a longstanding pleural infection such as persistent pleural effusion. It is caused by an extension of pus to nearby structures including the chest wall and is usually caused by Mycobacterium tuberculosis infection. It is difficult to diagnose since its features are similar to those of other disease entities such as malignancies; therefore, imaging tests such as a chest CT scan are helpful in establishing the diagnosis. In addition, other diagnostic tests such as acid-fast stain and GeneXpert may be falsely negative due to inadequate or incorrect sampling location. One such case is this 30-year-old female with chronic cough and recurrent pleural effusion that progressed to Empyema Necessitans presenting as an abdominal mass where sputum GeneXpert was negative, but aspirate of the abdominal mass showedMycobacterium tuberculosis. Prompt initiation of anti-tuberculosis treatment once diagnosis is confirmed as well as emphasizing its completion is imperative for definitive treatment. As such, family physicians have a vital role in navigating patients for further workup and necessary referrals for a multidisciplinary management especially in persistent disease processes as well as screening and treatment of the family for holistic care.
Human ; Female ; Adult: 25-44 Yrs Old ; Mycobacterium Tuberculosis
5.Mechanical Thrombectomy Versus Intravenous Thrombolysis in Distal Medium Vessel Acute Ischemic Stroke: A Multinational Multicenter Propensity Score-Matched Study
Hamza Adel SALIM ; Vivek YEDAVALLI ; Basel MUSMAR ; Nimer ADEEB ; Muhammed Amir ESSIBAYI ; Kareem El NAAMANI ; Nils HENNINGER ; Sri Hari SUNDARARAJAN ; Anna Luisa KÜHN ; Jane KHALIFE ; Sherief GHOZY ; Luca SCARCIA ; Benjamin Y.Q. TAN ; Benjamin PULLI ; Jeremy J. HEIT ; Robert W. REGENHARDT ; Nicole M. CANCELLIERE ; Joshua D. BERNSTOCK ; Aymeric ROUCHAUD ; Jens FIEHLER ; Sunil SHETH ; Ajit S. PURI ; Christian DYZMANN ; Marco COLASURDO ; Xavier BARREAU ; Leonardo RENIERI ; João Pedro FILIPE ; Pablo HARKER ; Razvan Alexandru RADU ; Thomas R. MAROTTA ; Julian SPEARS ; Takahiro OTA ; Ashkan MOWLA ; Pascal JABBOUR ; Arundhati BISWAS ; Frédéric CLARENÇON ; James E. SIEGLER ; Thanh N. NGUYEN ; Ricardo VARELA ; Amanda BAKER ; David ALTSCHUL ; Nestor R. GONZALEZ ; Markus A. MÖHLENBRUCH ; Vincent COSTALAT ; Benjamin GORY ; Christian Paul STRACKE ; Mohammad Ali AZIZ-SULTAN ; Constantin HECKER ; Hamza SHAIKH ; David S. LIEBESKIND ; Alessandro PEDICELLI ; Andrea M. ALEXANDRE ; Illario TANCREDI ; Tobias D. FAIZY ; Erwah KALSOUM ; Boris LUBICZ ; Aman B. PATEL ; Vitor Mendes PEREIRA ; Adrien GUENEGO ; Adam A. DMYTRIW ;
Journal of Stroke 2024;26(3):434-445
Background:
and Purpose The management of acute ischemic stroke (AIS) due to distal medium vessel occlusion (DMVO) remains uncertain, particularly in comparing the effectiveness of intravenous thrombolysis (IVT) plus mechanical thrombectomy (MT) versus IVT alone. This study aimed to evaluate the safety and efficacy in DMVO patients treated with either MT-IVT or IVT alone.
Methods:
This multinational study analyzed data from 37 centers across North America, Asia, and Europe. Patients with AIS due to DMVO were included, with data collected from September 2017 to July 2023. The primary outcome was functional independence, with secondary outcomes including mortality and safety measures such as types of intracerebral hemorrhage.
Results:
The study involved 1,057 patients before matching, and 640 patients post-matching. Functional outcomes at 90 days showed no significant difference between groups in achieving good functional recovery (modified Rankin Scale 0–1 and 0–2), with adjusted odds ratios (OR) of 1.21 (95% confidence interval [CI] 0.81 to 1.79; P=0.35) and 1.00 (95% CI 0.66 to 1.51; P>0.99), respectively. Mortality rates at 90 days were similar between the two groups (OR 0.75, 95% CI 0.44 to 1.29; P=0.30). The incidence of symptomatic intracerebral hemorrhage was comparable, but any type of intracranial hemorrhage was significantly higher in the MT-IVT group (OR 0.43, 95% CI 0.29 to 0.63; P<0.001).
Conclusion
The results of this study indicate that while MT-IVT and IVT alone show similar functional and mortality outcomes in DMVO patients, MT-IVT presents a higher risk of hemorrhagic complications, thus MT-IVT may not routinely offer additional benefits over IVT alone for all DMVO stroke patients. Further prospective randomized trials are needed to identify patient subgroups most likely to benefit from MT-IVT treatment in DMVO.
6.Edema and hematoma after local anesthesia via posterior superior alveolar nerve block: a case report
Aline Louise Nascimento MARQUES ; Sidney R. FIGUEROBA ; Marco Antonio TRIDAPALLI MAFRA ; Francisco Carlos GROPPO
Journal of Dental Anesthesia and Pain Medicine 2022;22(3):227-231
Although rare, complications can occur with anesthetic procedures. The posterior superior alveolar nerve (PSAN) block anesthetic technique has a high success rate, but positive aspiration can cause bruising, transient diplopia, blurred vision, and temporary blindness in approximately 3% cases. When edema occurs, it is occasionally massive, especially in the infratemporal fossa, and the resulting hematoma is usually unsightly. A 20-year-old woman presented with massive edema followed by hematoma in the upper right jaw immediately after PSAN block administration, which subsequently spread to the oral mucosa. The patient did not report any complications during the anesthetic procedure. However, after the injection was administered, the patient experienced anesthetic sensations, which rapidly evolved to facial edema. There was mild pain, but without intraoral or extraoral bleeding.The patient was prescribed medicines and instructed to perform contrast therapy. Although hematomas and edema are rare, they are difficult to prevent. The choice of local anesthetic and appropriate application of the anesthetic technique can minimize their occurrence.
7.Computed Tomography Pulmonary Angiography during Pregnancy: Radiation Dose of Commonly Used Protocols and the Effect of Scan Length Optimization
Babs M F HENDRIKS ; Roald S SCHNERR ; Gianluca MILANESE ; Cécile R L P N JEUKENS ; Sandra NIESEN ; Nienke G EIJSVOOGEL ; Joachim E WILDBERGER ; Marco DAS
Korean Journal of Radiology 2019;20(2):313-322
OBJECTIVE: To evaluate the radiation dose for pregnant women and fetuses undergoing commonly used computed tomography of the pulmonary arteries (CTPA) scan protocols and subsequently evaluate the simulated effect of an optimized scan length. MATERIALS AND METHODS: A total of 120 CTPA datasets were acquired using four distinctive scan protocols, with 30 patients per protocol. These datasets were mapped to Cristy phantoms in order to simulate pregnancy and to assess the effect of an effective radiation dose (in mSv) in the first, second, or third trimester of pregnancy, including a simulation of fetal dose in second and third trimesters. The investigated scan protocols involved a 64-slice helical scan at 120 kVp, a high-pitch dual source acquisition at 100 kVp, a dual-energy acquisition at 80/140 kVp, and an automated-kV-selection, high pitch helical scan at a reference kV of 100 kVref. The effective dose for women and fetuses was simulated before and after scan length adaptation. The original images were interpreted before and after scan length adaptations to evaluate potentially missed diagnoses. RESULTS: Large inter-scanner and inter-protocol variations were found; application of the latest technology decreased the dose for non-pregnant women by 69% (7.0–2.2 mSv). Individual scan length optimization proved safe and effective, decreasing the fetal dose by 76–83%. Nineteen (16%) cases of pulmonary embolism were diagnosed and, after scan length optimization, none were missed. CONCLUSION: Careful CTPA scan protocol selection and additional optimization of scan length may result in significant radiation dose reduction for a pregnant patient and her fetus, whilst maintaining diagnostic confidence.
Angiography
;
Dataset
;
Diagnosis
;
Female
;
Fetus
;
Humans
;
Pregnancy Trimester, Third
;
Pregnancy
;
Pregnant Women
;
Pulmonary Artery
;
Pulmonary Embolism
8.Project Hawkeye: A cross-sectional study on the prevalence of undetected refractive errors in schoolage children
Gabrielle Delos H. Reyes ; Jan Erik B. Detran ; Maria Immanuelle C. Devela ; Khia Cates N. Devoma ; Miguel Enrico D. Dial ; Jurish Candice E. Diaz ; Rafael Jose A. Dimaculangan ; Alejandro S. Dizon Jr. ; Dean Marco R. Dizon ; Patricia Mae F. Domingo ; Banette Lysa F. Estacio ; Remigio Jay-Ar Z. Butacan IV ; Fay Charmaine S. Cruz
Health Sciences Journal 2017;6(2):69-75
Introduction:
In the Philippines, essential eye care services are not easily accessible especially
for those in lower income groups, putting public elementary school students at risk for underdiagnosis of problems in visual acuity. The objective of this investigation was to determine
prevalence of undetected refractive errors among public elementary students using the Welch Allyn
Spot™ Vision Screener.
Methods :
A cross-sectional design was used in this investigation to estimate the prevalence of
uncorrected refractive errors in the first grade students in San Perfecto Elementary School using
Welch Allyn Spot™ Vision Screener (Photoscreener). Eligible students who gave informed consent
and assent answered a questionnaire and underwent an eye examination. The prevalence of
undetected errors of refraction were computed for the sample population and for selected demographic
variables.
Results :
Approximately one out of four students (24.53%) had errors of refraction, with the most
common type being astigmatism (22.64%), followed by myopia (3.77%) and hyperopia (2.83%).
Conclusion
This study revealed a high prevalence of undetected refractive errors among school-age
children, higher than current published data (5%) in the Philippines.
Cross-Sectional Studies
;
Refractive Errors
9.Prolonged Practice of Swimming Is Negatively Related to Bone Mineral Density Gains in Adolescents.
Marcelo R RIBEIRO-DOS-SANTOS ; Kyle R LYNCH ; Ricardo R AGOSTINETE ; Santiago MAILLANE-VANEGAS ; Bruna TURI-LYNCH ; Igor H ITO ; Rafael LUIZ-DE-MARCO ; Mario A RODRIGUES-JUNIOR ; Rômulo A FERNANDES
Journal of Bone Metabolism 2016;23(3):149-155
BACKGROUND: The practice of swimming in "hypogravity" conditions has potential to decrease bone formation because it decreases the time engaged in weight-bearing activities usually observed in the daily activities of adolescents. Therefore, adolescents competing in national levels would be more exposed to these deleterious effects, because they are engaged in long routines of training during most part of the year. To analyze the effect of swimming on bone mineral density (BMD) gain among adolescents engaged in national level competitions during a 9-month period. METHODS: Fifty-five adolescents; the control group contained 29 adolescents and the swimming group was composed of 26 athletes. During the cohort study, BMD, body fat (BF) and fat free mass (FFM) were assessed using a dual-energy x-ray absorptiometry scanner. Body weight was measured with an electronic scale, and height was assessed using a stadiometer. RESULTS: During the follow-up, swimmers presented higher gains in FFM (Control 2.35 kg vs. Swimming 5.14 kg; large effect size [eta-squared (ES-r)=0.168]) and BMD-Spine (Swimming 0.087 g/cm² vs. Control 0.049 g/cm²; large effect size [ES-r=0.167]) compared to control group. Male swimmers gained more FFM (Male 10.63% vs. Female 3.39%) and BMD-Spine (Male 8.47% vs. Female 4.32%) than females. Longer participation in swimming negatively affected gains in upper limbs among males (r=-0.438 [-0.693 to -0.085]), and in spine among females (r=-0.651 [-0.908 to -0.036]). CONCLUSIONS: Over a 9-month follow-up, BMD and FFM gains were more evident in male swimmers, while longer engagement in swimming negatively affected BMD gains, independently of sex.
Absorptiometry, Photon
;
Adipose Tissue
;
Adolescent*
;
Athletes
;
Body Weight
;
Bone Density*
;
Cohort Studies
;
Female
;
Follow-Up Studies
;
Humans
;
Male
;
Osteogenesis
;
Spine
;
Sports
;
Swimming*
;
Upper Extremity
;
Weight-Bearing
10.Gastric Tube Motility Patterns in Patients After Esophageal Resection with Gastric Pull-up.
Priscila R ARMIJO ; Fernando A M HERBELLA ; Marco G PATTI
Journal of Neurogastroenterology and Motility 2016;22(1):157-158
No abstract available.
Humans


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